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The map label for this gene is fur [H]

Identifier: 116492189

GI number: 116492189

Start: 433029

End: 433478

Strand: Direct

Name: fur [H]

Synonym: PEPE_0386

Alternate gene names: 116492189

Gene position: 433029-433478 (Clockwise)

Preceding gene: 116492188

Following gene: 116492190

Centisome position: 23.63

GC content: 35.33

Gene sequence:

>450_bases
TTGAACAAAACTAGTAAAGAAATTGCGGTAAAAATTTTAAAAGCTAATAACTATAAATTAACTAAACAACGCCAGAGCTT
ACTCAATATTCTAGCTATCCATGAGGACCGCTACATGGAATTGACGGAGTTAGATCAGTTAATGCGCCAAGAGTATCCTA
AAATGAGCTACAATACAATTTATCGAAACATTAAGGAATTTTCTGAAATTGGGATTGTTGAAGAAAATCAAAATGAAAAT
GATGGTAAAACCGAAGTAAAGTTAGATTGTAATGAACGGCACACTCATCATCACCATTTTATTTGTAATAACTGTGGCAA
AGTACGGGAACTCCAAATGTGCCCTCTAAGCTTCTTTAGTGAGCAATTGCCAGGGGCTGAGATTACGGGACATCATTTTG
AGTTATATGGGTTATGCGCAGATTGTAAGCAATTAATGGGTGAAAAGTAG

Upstream 100 bases:

>100_bases
AATTTTATCAAAGAGTTAAAGAAGCAACCAAAAAGATACCAAATGAAGGTTAATTATGGTAGGGTAAAACGTAATGATTA
CTATTTAGAGGTGCAGATTT

Downstream 100 bases:

>100_bases
ATGATTTTTTTAAGTTATTGCAAACTTAATCAATATTTGAAATAAAAGCTAAATATTTTTGATATGCTTTTTTTAAAGAC
GGAGGGAAAGAGAAATGGCA

Product: Fe2+/Zn2+ uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNKTSKEIAVKILKANNYKLTKQRQSLLNILAIHEDRYMELTELDQLMRQEYPKMSYNTIYRNIKEFSEIGIVEENQNEN
DGKTEVKLDCNERHTHHHHFICNNCGKVRELQMCPLSFFSEQLPGAEITGHHFELYGLCADCKQLMGEK

Sequences:

>Translated_149_residues
MNKTSKEIAVKILKANNYKLTKQRQSLLNILAIHEDRYMELTELDQLMRQEYPKMSYNTIYRNIKEFSEIGIVEENQNEN
DGKTEVKLDCNERHTHHHHFICNNCGKVRELQMCPLSFFSEQLPGAEITGHHFELYGLCADCKQLMGEK
>Mature_149_residues
MNKTSKEIAVKILKANNYKLTKQRQSLLNILAIHEDRYMELTELDQLMRQEYPKMSYNTIYRNIKEFSEIGIVEENQNEN
DGKTEVKLDCNERHTHHHHFICNNCGKVRELQMCPLSFFSEQLPGAEITGHHFELYGLCADCKQLMGEK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17506; Mature: 17506

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTSKEIAVKILKANNYKLTKQRQSLLNILAIHEDRYMELTELDQLMRQEYPKMSYNTI
CCCCHHHHEEHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHH
YRNIKEFSEIGIVEENQNENDGKTEVKLDCNERHTHHHHFICNNCGKVRELQMCPLSFFS
HHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCHHHHCCCHHHHH
EQLPGAEITGHHFELYGLCADCKQLMGEK
HHCCCCCCCCCEEHEEHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTSKEIAVKILKANNYKLTKQRQSLLNILAIHEDRYMELTELDQLMRQEYPKMSYNTI
CCCCHHHHEEHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHH
YRNIKEFSEIGIVEENQNENDGKTEVKLDCNERHTHHHHFICNNCGKVRELQMCPLSFFS
HHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCHHHHCCCHHHHH
EQLPGAEITGHHFELYGLCADCKQLMGEK
HHCCCCCCCCCEEHEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA