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The map label for this gene is psaA [H]

Identifier: 116492093

GI number: 116492093

Start: 334099

End: 334986

Strand: Direct

Name: psaA [H]

Synonym: PEPE_0289

Alternate gene names: 116492093

Gene position: 334099-334986 (Clockwise)

Preceding gene: 116492090

Following gene: 116492094

Centisome position: 18.23

GC content: 35.81

Gene sequence:

>888_bases
ATGCGAAAAAAAATAATTTGGTTAGTGTCAATGTTATTGTTTAGCACTATTTTTGTTGCGGGATGTGCTGGACCTAAAAG
TAAGTCCAGTGGCAAAGTAGAAGTGATTAGTACACTTAACTTTTATGGAGAAGTGGCTAAAAAGGTTGGCGGAAATCGAG
TGCAGGTTACCAACATTATTGATAATCCAGCAGTCGATCCCCATGATTTTGAGCCGACAACTAAGACGGCTAAATTAATG
ACCGACGCGGATATTGTAGTTGAAAATGGAGTAGGAACAGATACTTGGGTCCAAAAAATCACTCCTCAAAAAAAGCAGCT
TAAGGTTTTAAATATGGGGAAACTCACGGGTAAAGTTGATGGTGATAACCCACATTTGTGGTATAAATTATCAACAATGA
AAACCTTAGCTAACCATTTAGCTAAGGAATTAGGGAAAAAGGATCCAAAACATCAAAAAGAATTTACCGAAAATGCTAAG
AAATATGTTGAATCACTTCAACCAATCCAACAAAAGATTGATCAAATTAGAGCAGAAAGTACTGGCAAAAAAGTAGCAGT
TACAGAGCCAGTATATGATTACACGCTGGATGAGCTCGGATATAAAGTTAGCGACCGAGCTTTCGCTTTAGCAATTGAAA
ATGAAACAGATCCATCGCCTAAAATGGTGGAAAAATTACAAAAAGATGTAAAACAAAAACGGATTGAATTTATTGTAAAT
AATCAACAAACTGGTAATAAAGTAATCGATGAGCTTCTAAAGCTAGCTAAGAAAAACGATACTCCAATCGTGAACGTCAC
AGAGACGATGCCGAAGGGAAAAAATTATCAAACGTGGATGCTTTCACAGTTAAACCAAATTAGTAAAATACAAGAGGGTA
AAAATTAA

Upstream 100 bases:

>100_bases
TTTTTGAAAACGTTATCTTAAAATTAGACGTCCCATATTAAAATTTTTTTGTTATAATTGAATATTGTAAATAGTAATTA
TTACTCTTTAGGAGAAAGAA

Downstream 100 bases:

>100_bases
TGACTGAAACGCTTGTTCAGGTTCAAAAATTAGCAATGGATTTTCCAGGGCAAAAATTATTTAATAATTTGAGTTTTGAT
GTAGATCGTCGTGACTTTCT

Product: ABC-type metal ion transport system, periplasmic component/surface adhesin

Products: NA

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRKKIIWLVSMLLFSTIFVAGCAGPKSKSSGKVEVISTLNFYGEVAKKVGGNRVQVTNIIDNPAVDPHDFEPTTKTAKLM
TDADIVVENGVGTDTWVQKITPQKKQLKVLNMGKLTGKVDGDNPHLWYKLSTMKTLANHLAKELGKKDPKHQKEFTENAK
KYVESLQPIQQKIDQIRAESTGKKVAVTEPVYDYTLDELGYKVSDRAFALAIENETDPSPKMVEKLQKDVKQKRIEFIVN
NQQTGNKVIDELLKLAKKNDTPIVNVTETMPKGKNYQTWMLSQLNQISKIQEGKN

Sequences:

>Translated_295_residues
MRKKIIWLVSMLLFSTIFVAGCAGPKSKSSGKVEVISTLNFYGEVAKKVGGNRVQVTNIIDNPAVDPHDFEPTTKTAKLM
TDADIVVENGVGTDTWVQKITPQKKQLKVLNMGKLTGKVDGDNPHLWYKLSTMKTLANHLAKELGKKDPKHQKEFTENAK
KYVESLQPIQQKIDQIRAESTGKKVAVTEPVYDYTLDELGYKVSDRAFALAIENETDPSPKMVEKLQKDVKQKRIEFIVN
NQQTGNKVIDELLKLAKKNDTPIVNVTETMPKGKNYQTWMLSQLNQISKIQEGKN
>Mature_295_residues
MRKKIIWLVSMLLFSTIFVAGCAGPKSKSSGKVEVISTLNFYGEVAKKVGGNRVQVTNIIDNPAVDPHDFEPTTKTAKLM
TDADIVVENGVGTDTWVQKITPQKKQLKVLNMGKLTGKVDGDNPHLWYKLSTMKTLANHLAKELGKKDPKHQKEFTENAK
KYVESLQPIQQKIDQIRAESTGKKVAVTEPVYDYTLDELGYKVSDRAFALAIENETDPSPKMVEKLQKDVKQKRIEFIVN
NQQTGNKVIDELLKLAKKNDTPIVNVTETMPKGKNYQTWMLSQLNQISKIQEGKN

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33159; Mature: 33159

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKIIWLVSMLLFSTIFVAGCAGPKSKSSGKVEVISTLNFYGEVAKKVGGNRVQVTNII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEEC
DNPAVDPHDFEPTTKTAKLMTDADIVVENGVGTDTWVQKITPQKKQLKVLNMGKLTGKVD
CCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEC
GDNPHLWYKLSTMKTLANHLAKELGKKDPKHQKEFTENAKKYVESLQPIQQKIDQIRAES
CCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGKKVAVTEPVYDYTLDELGYKVSDRAFALAIENETDPSPKMVEKLQKDVKQKRIEFIVN
CCCEEEEECCHHHHHHHHHCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
NQQTGNKVIDELLKLAKKNDTPIVNVTETMPKGKNYQTWMLSQLNQISKIQEGKN
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKKIIWLVSMLLFSTIFVAGCAGPKSKSSGKVEVISTLNFYGEVAKKVGGNRVQVTNII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEEC
DNPAVDPHDFEPTTKTAKLMTDADIVVENGVGTDTWVQKITPQKKQLKVLNMGKLTGKVD
CCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEC
GDNPHLWYKLSTMKTLANHLAKELGKKDPKHQKEFTENAKKYVESLQPIQQKIDQIRAES
CCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGKKVAVTEPVYDYTLDELGYKVSDRAFALAIENETDPSPKMVEKLQKDVKQKRIEFIVN
CCCEEEEECCHHHHHHHHHCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
NQQTGNKVIDELLKLAKKNDTPIVNVTETMPKGKNYQTWMLSQLNQISKIQEGKN
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8945574; 9767595; 11463916; 9379902 [H]