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The map label for this gene is katE [H]

Identifier: 116328471

GI number: 116328471

Start: 2114846

End: 2116303

Strand: Reverse

Name: katE [H]

Synonym: LBL_1816

Alternate gene names: 116328471

Gene position: 2116303-2114846 (Counterclockwise)

Preceding gene: 116328472

Following gene: 116328468

Centisome position: 58.55

GC content: 44.03

Gene sequence:

>1458_bases
ATGAATAAAAAGACTCTTACTACGGCTGGAGGCCATCCGGTCGCACAAAATCAACATTCCATCACGGCTGGACCCAGAGG
TCCAGTCCTTATTCAGGATACTCATCTCATTGAAAAACTTGCCCACTTCAATCGGGAACGAATTCCAGAAAGAGTCGTTC
ACGCAAAGGGAGCGGGGGCTTATGGAACTCTGACAATCACGCGCGATCTTACGAAGTATTCTAGGGCCTCCGTTTTTTCA
AAGGTGGGAAAACAAACTTCTCTCTTTCTACGTTTTTCAACGGTTGCGGGTGAAAAAGGTTCAGCGGATACGGAAAGAGA
TCCAAGAGGTTTTGCGATCAAGTTTTATACGGACGAAGGGATTTGGGATCTTGTGGGAAATAATACACCTGTATTCTTTG
AAAGAGATCCGTTGAAATTTCCGGATTTTATCCATTCACAAAAAAGAGATCCGATTACGGGTTATAAGAATCCGTTTCGT
ATGTGGGATTATTGGGCAAAAGCTCCCGAAGCACTGCACCAAATTACGATTCTTTTCGGAGATAGGGGAATTCCGGACGG
TTATCGTTTTATGAACGGCTACGGAAGTCACACTTTTGGGCTTTGGAATTCTCAAGGACAACGTTTTTGGGTAAAATTCC
ACTTTAAGACCATGCAAGGAATCAAAAATCTGACTTCGGAAAGGGCATCTGCGTTAGCCGGAACTGATCCGGATTACGCG
GCTAGGGATTTGTTTGAGGCGATTGAAAGGAAGGAATTTCCTAAGTGGAAGTTTTGTCTACAGATCATGCCGGAGAAGGA
GGCTGAAACATATCGATTCAATCCGTTCGATCTCACAAAGGTCTGGTCTCACAAAGATTATCCTTTGATCGAAGCGGGAG
TGTTGGAATTGAACGCCAATCCTAAGAATTATTTCGAGGAAGTAGAGCAGGCGGCCTTTTCGCCTTCCAACATGCCTCCG
GGAATAGGCGCTTCTCCGGATAAAATGTTGCAAGGAAGGTTATTTGCATATCCGGATGCTCAGAGATATCGTTTAGGGAT
ACGATATCAACAACTTCCGGTAAATAGGCCTAAGAACTTAGTGAACGTTTATCATAGGGATGGAAATACAAAGTTTCAAT
ATGATGGAAACTACGATAATTATGAGCCGAACGGTTTTGAGGGGCCGGTACAAGATTCTTCGTACGGGGAACCTCCTTTA
AAAATCTCTGGAGATGCAGATCGTTACGATTCCCACAAAGGAAACGACGATTATTCTCAAGCAGGGGATTTGTATCGAAT
CATGAGTGTGGAGGAAAGAGAAAGGCTCACTTCTGCGATCGCTTCCACGATGCATGGTCTTCCTAAAAGTGTAATCGTTG
CGAATCTCAAACATTTCTACCTCTGCGACCCGGAATACGGAACCAAACTGGCCGAAAAAGTAGAAATTTCCTTAGAAGAT
ATAAAAACCTGTCCCTAG

Upstream 100 bases:

>100_bases
AAACTTCTAAGTGAATCCGAGTCAACTCGGTTTCAGAGATTATTAACTTTTTTTAAATCTTGGATTTTATATATCATTCA
AATTACAAAAGGAGAACACG

Downstream 100 bases:

>100_bases
TTCCCACTTCCTACATAATAGGGTGTCGTGAATTTTGAAACGAGTTCCTATTTAGAAATAGAATCCTAGACACTCTATTA
TGTAGTTTTGAGTGAAAGAA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNKKTLTTAGGHPVAQNQHSITAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITRDLTKYSRASVFS
KVGKQTSLFLRFSTVAGEKGSADTERDPRGFAIKFYTDEGIWDLVGNNTPVFFERDPLKFPDFIHSQKRDPITGYKNPFR
MWDYWAKAPEALHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSQGQRFWVKFHFKTMQGIKNLTSERASALAGTDPDYA
ARDLFEAIERKEFPKWKFCLQIMPEKEAETYRFNPFDLTKVWSHKDYPLIEAGVLELNANPKNYFEEVEQAAFSPSNMPP
GIGASPDKMLQGRLFAYPDAQRYRLGIRYQQLPVNRPKNLVNVYHRDGNTKFQYDGNYDNYEPNGFEGPVQDSSYGEPPL
KISGDADRYDSHKGNDDYSQAGDLYRIMSVEERERLTSAIASTMHGLPKSVIVANLKHFYLCDPEYGTKLAEKVEISLED
IKTCP

Sequences:

>Translated_485_residues
MNKKTLTTAGGHPVAQNQHSITAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITRDLTKYSRASVFS
KVGKQTSLFLRFSTVAGEKGSADTERDPRGFAIKFYTDEGIWDLVGNNTPVFFERDPLKFPDFIHSQKRDPITGYKNPFR
MWDYWAKAPEALHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSQGQRFWVKFHFKTMQGIKNLTSERASALAGTDPDYA
ARDLFEAIERKEFPKWKFCLQIMPEKEAETYRFNPFDLTKVWSHKDYPLIEAGVLELNANPKNYFEEVEQAAFSPSNMPP
GIGASPDKMLQGRLFAYPDAQRYRLGIRYQQLPVNRPKNLVNVYHRDGNTKFQYDGNYDNYEPNGFEGPVQDSSYGEPPL
KISGDADRYDSHKGNDDYSQAGDLYRIMSVEERERLTSAIASTMHGLPKSVIVANLKHFYLCDPEYGTKLAEKVEISLED
IKTCP
>Mature_485_residues
MNKKTLTTAGGHPVAQNQHSITAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITRDLTKYSRASVFS
KVGKQTSLFLRFSTVAGEKGSADTERDPRGFAIKFYTDEGIWDLVGNNTPVFFERDPLKFPDFIHSQKRDPITGYKNPFR
MWDYWAKAPEALHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSQGQRFWVKFHFKTMQGIKNLTSERASALAGTDPDYA
ARDLFEAIERKEFPKWKFCLQIMPEKEAETYRFNPFDLTKVWSHKDYPLIEAGVLELNANPKNYFEEVEQAAFSPSNMPP
GIGASPDKMLQGRLFAYPDAQRYRLGIRYQQLPVNRPKNLVNVYHRDGNTKFQYDGNYDNYEPNGFEGPVQDSSYGEPPL
KISGDADRYDSHKGNDDYSQAGDLYRIMSVEERERLTSAIASTMHGLPKSVIVANLKHFYLCDPEYGTKLAEKVEISLED
IKTCP

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=469, Percent_Identity=55.4371002132196, Blast_Score=528, Evalue=1e-150,
Organism=Escherichia coli, GI48994891, Length=387, Percent_Identity=45.2196382428941, Blast_Score=340, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI71998444, Length=474, Percent_Identity=51.2658227848101, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI25147792, Length=474, Percent_Identity=51.4767932489451, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=51.6949152542373, Blast_Score=502, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6320462, Length=458, Percent_Identity=45.4148471615721, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321525, Length=465, Percent_Identity=40.4301075268817, Blast_Score=350, Evalue=4e-97,
Organism=Drosophila melanogaster, GI17981717, Length=478, Percent_Identity=49.7907949790795, Blast_Score=484, Evalue=1e-137,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=45.8333333333333, Blast_Score=446, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55232; Mature: 55232

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTLTTAGGHPVAQNQHSITAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGA
CCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCC
YGTLTITRDLTKYSRASVFSKVGKQTSLFLRFSTVAGEKGSADTERDPRGFAIKFYTDEG
EEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCC
IWDLVGNNTPVFFERDPLKFPDFIHSQKRDPITGYKNPFRMWDYWAKAPEALHQITILFG
EEECCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
DRGIPDGYRFMNGYGSHTFGLWNSQGQRFWVKFHFKTMQGIKNLTSERASALAGTDPDYA
CCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHH
ARDLFEAIERKEFPKWKFCLQIMPEKEAETYRFNPFDLTKVWSHKDYPLIEAGVLELNAN
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEECCC
PKNYFEEVEQAAFSPSNMPPGIGASPDKMLQGRLFAYPDAQRYRLGIRYQQLPVNRPKNL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEECCCHHHEEECCEEEECCCCCCHHH
VNVYHRDGNTKFQYDGNYDNYEPNGFEGPVQDSSYGEPPLKISGDADRYDSHKGNDDYSQ
HEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AGDLYRIMSVEERERLTSAIASTMHGLPKSVIVANLKHFYLCDPEYGTKLAEKVEISLED
HCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHEEEHHH
IKTCP
HCCCC
>Mature Secondary Structure
MNKKTLTTAGGHPVAQNQHSITAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGA
CCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCC
YGTLTITRDLTKYSRASVFSKVGKQTSLFLRFSTVAGEKGSADTERDPRGFAIKFYTDEG
EEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCC
IWDLVGNNTPVFFERDPLKFPDFIHSQKRDPITGYKNPFRMWDYWAKAPEALHQITILFG
EEECCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
DRGIPDGYRFMNGYGSHTFGLWNSQGQRFWVKFHFKTMQGIKNLTSERASALAGTDPDYA
CCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHH
ARDLFEAIERKEFPKWKFCLQIMPEKEAETYRFNPFDLTKVWSHKDYPLIEAGVLELNAN
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEECCC
PKNYFEEVEQAAFSPSNMPPGIGASPDKMLQGRLFAYPDAQRYRLGIRYQQLPVNRPKNL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEECCCHHHEEECCEEEECCCCCCHHH
VNVYHRDGNTKFQYDGNYDNYEPNGFEGPVQDSSYGEPPLKISGDADRYDSHKGNDDYSQ
HEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AGDLYRIMSVEERERLTSAIASTMHGLPKSVIVANLKHFYLCDPEYGTKLAEKVEISLED
HCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHEEEHHH
IKTCP
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9358059 [H]