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The map label for this gene is ykkD [H]

Identifier: 116327438

GI number: 116327438

Start: 729232

End: 729552

Strand: Direct

Name: ykkD [H]

Synonym: LBL_0654

Alternate gene names: 116327438

Gene position: 729232-729552 (Clockwise)

Preceding gene: 116327435

Following gene: 116327439

Centisome position: 20.18

GC content: 41.74

Gene sequence:

>321_bases
ATGGCTTGGATTTATCTTATCATCGCTTCTACATTCGAGATCGGATTTACGACTTGCCTCAAGTTATCCGATAATTTTAC
TAAACCGACATGGGTCGGAGGTTTTGTGGTTTCTGCGGTTTTTAGTTTGGCGTTTCTGAACAAGGCGGTTCAGACGATTC
CGATGGGAACCGCTTACGCAATTTGGACCGGTTTGGGGGCGGCAGGAACCATACTTGTCGGTATCGTAATTCACGGAGAA
CCTATCGATTTTTGGAGAGGATTTTTTTTGTCTACTCTAATTCTTTCTGTTTTAGGTCTTAAATTTTTAGTTTCGGAATA
A

Upstream 100 bases:

>100_bases
GGATAAAAATTCAAGTTTATCGGATTTCTTTCGTGGTCGACAATGATCGGGATTCTTCGATAATGAGTTGATATCCATCT
AGAATAAAAGAGTTTGAGTT

Downstream 100 bases:

>100_bases
AGGAATTTAAAAGCCGATTTTATTTAAAGTCTGTTCCAAAATCTTAAAATAACGCGAGTTAACAGATACAAAAGCGATTG
AAGCGTAGTGGAACTAGAGC

Product: cation efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAWIYLIIASTFEIGFTTCLKLSDNFTKPTWVGGFVVSAVFSLAFLNKAVQTIPMGTAYAIWTGLGAAGTILVGIVIHGE
PIDFWRGFFLSTLILSVLGLKFLVSE

Sequences:

>Translated_106_residues
MAWIYLIIASTFEIGFTTCLKLSDNFTKPTWVGGFVVSAVFSLAFLNKAVQTIPMGTAYAIWTGLGAAGTILVGIVIHGE
PIDFWRGFFLSTLILSVLGLKFLVSE
>Mature_105_residues
AWIYLIIASTFEIGFTTCLKLSDNFTKPTWVGGFVVSAVFSLAFLNKAVQTIPMGTAYAIWTGLGAAGTILVGIVIHGEP
IDFWRGFFLSTLILSVLGLKFLVSE

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=38.2352941176471, Blast_Score=71, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11494; Mature: 11363

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIYLIIASTFEIGFTTCLKLSDNFTKPTWVGGFVVSAVFSLAFLNKAVQTIPMGTAYA
CEEEEEEEHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGLGAAGTILVGIVIHGEPIDFWRGFFLSTLILSVLGLKFLVSE
HHHCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWIYLIIASTFEIGFTTCLKLSDNFTKPTWVGGFVVSAVFSLAFLNKAVQTIPMGTAYA
EEEEEEEHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGLGAAGTILVGIVIHGEPIDFWRGFFLSTLILSVLGLKFLVSE
HHHCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA