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The map label for this gene is 116327425

Identifier: 116327425

GI number: 116327425

Start: 706431

End: 708497

Strand: Direct

Name: 116327425

Synonym: LBL_0635

Alternate gene names: NA

Gene position: 706431-708497 (Clockwise)

Preceding gene: 116327424

Following gene: 116327426

Centisome position: 19.54

GC content: 43.49

Gene sequence:

>2067_bases
ATGGATAAAGAAATCCGAAAAAACAGGTTGTTCTTAGAGGGAATCGAGGAGAAAGAACTTTATTTTCCGGAGGATCAAGA
ACCGGTTCGGATTCGTAGGTCATATAATAAACTTCTTATATTCTGGATTTTAATGGGTCTTCTTGTTTTAGGCGGACTCG
GTTTTGCCTTATATCATCAATTTTTGCGTTCTTCTTCTCCCGAATCCGAACTTGCGGGAGCCTTCAACAAAGATCTGATT
CAAAATAAGTCGGATATCAATCGTCTATTAGAAAGACCTTATCTTCCCGACGGAAACGCAAATCCACAGTTGACGAAATG
TATCAATCTTTATAAGGAAAGATTTACCAGACAGGCCTTCGATACTTGTAATGAATTTCTGAATTCCGCGGGAACACAAG
AAGAGAAGTCGATCGCGCTTACGGTTCTCGGAGTGATTCACGACGAAAGCGGGCGTTATCCGCAGGCGATTGAAAGACTT
CAAAAAGCGGTTCAGTACGATCCTAAAAATTTTTACGCTTATTACAACTTGACTCTTTCCTACAAACACGCGGGGAGATT
CGCGGACGCGAGAATGGCGGCTCTTAAGGCAAAGGAAATTGCACCGAATGATCCGAGAGTCTCTCTGCTTGCGGGGAATT
TATTCAACGAGTTGAACGATCCCGACGCGGCGATCGACGCGTATAAAGAGGGACTTTCTTCTTCTCCCGATGATATGTAT
CTGACCTACAATCTTGCGGTCAGTTATTTTAAAAAGGGAGAGATTCCTCAAGCCGAAGAGGAATTTAAGAAAGTAGTGAC
AAAGACCCCTTCGGGAAGACTCGCGGCCTTATCGTATTCTTATCTGGGGAACATCGCTTACAACAAGCAGGACTACAAAG
GTGCGGAATATTATTTTCGTCAGGCAAGTGCACTTTCTCCAAACGAAGCCAAGTATCTTTACAATCTCGCTGTCGTATTA
CAAAAGAATGGGAATAAAGAGGAGGCGCTGAAGTATCTGGAACTGGCGAGAGACGCCGGCGCAAACGATCCCGAAATCTA
CAGACTGATTGCGGAAGGATTTTCCAATTTGAATCAGGGAGAAATGTCCATCTCCGCACTTCAAAAAAGTTTAAAGTATA
ATCCGACGGATCTCGATTCTCTTTTTCAACTTGCGGAAGCATACTACAACAAAGGCGACCTTCTTTCCGCCGAAGAAACG
TATCGTAGGATCGTGTCTTCCACTCCGGGAGATAGTTTTACGGAGACTGCGCTTATCAATTTGGGAGTGGTTTTGGATCA
GATGGAGCGTTATTCCGAAGCAATCACGGCTTTGAGTCGTGTAGTCGATCTCAATCCGAAAAACGCGAAGGCGTATCACA
CGTTGGGACTTGTTTATAAACATTCCGGGAATGGGACTCTTGCCATCGAAAATTGGAGAAAATCCATTGCGATCGAGCCG
GAAAACATTCAAAGTCGAGAAGCTCTCGGTGATTATCTATTTGAAAATAAATTCTTTCGAGAAGCGGTGGAAGAATACAT
CGGAGTCGTAAAACACAAAGACGACGCTTACAAAGTTTATCTCAAAATGGCTGAGGCCTATATGGGAATGCAGGATGATG
TCAACGCCGAGAAGATTCTTTTGAAGGTATTAAACACTTCGAAAGACGGTACGGATTTGAAAAACGCCCATAAGAAATTA
GCTTTATTGTATAATAAATCTAAAGATCCCGATTTAAAAAATAGGGCCAAGGACGAAGCGTTTCGATCCGCTCATATGGA
TCCGGAAGATATGGAAGGTCGATTGGTACTTTCAAAAATTCTAATAGATTCTAATTCGATTTTGGACCGTGAGAAAGCGA
TCGACGAATTGATCGCCATCGTAAGATCCGATGTCAGACCGAAAATCGCCGCGACCGCATACAACTATCTAGGAATCTGT
TATTATAAAAACGGGGAATTTAAAAGGGCGGTTCGAGCGTTTCAGAGTTCGATTGACTTGGATCCTTCCTTGTCCGAAGC
ATACGAGAACAAACGCGCCGCATCCGCCGCTTTGGAGGAATCTACACGTAGAGAGGGGTTTTTCTGA

Upstream 100 bases:

>100_bases
GACGAAGCGGTGGAACTTACGAAAGAATTTGAAAGCGAAGAGTCCGCCCGGTTCGTGAACGGAATCCTGGACGCAATTCT
CAAAAACGAAACCAAATCCG

Downstream 100 bases:

>100_bases
AGAATTTCTTTTTTAGCGTTTTTATTCCATTCTTTCTCATCTCTTCGATTGCCGCCGCAGAAACTCTAAAAGACGAATTT
AAGGAAAATGTATTGAGTTT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MDKEIRKNRLFLEGIEEKELYFPEDQEPVRIRRSYNKLLIFWILMGLLVLGGLGFALYHQFLRSSSPESELAGAFNKDLI
QNKSDINRLLERPYLPDGNANPQLTKCINLYKERFTRQAFDTCNEFLNSAGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAVQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPNDPRVSLLAGNLFNELNDPDAAIDAYKEGLSSSPDDMY
LTYNLAVSYFKKGEIPQAEEEFKKVVTKTPSGRLAALSYSYLGNIAYNKQDYKGAEYYFRQASALSPNEAKYLYNLAVVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDLDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYSEAITALSRVVDLNPKNAKAYHTLGLVYKHSGNGTLAIENWRKSIAIEP
ENIQSREALGDYLFENKFFREAVEEYIGVVKHKDDAYKVYLKMAEAYMGMQDDVNAEKILLKVLNTSKDGTDLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPEDMEGRLVLSKILIDSNSILDREKAIDELIAIVRSDVRPKIAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEESTRREGFF

Sequences:

>Translated_688_residues
MDKEIRKNRLFLEGIEEKELYFPEDQEPVRIRRSYNKLLIFWILMGLLVLGGLGFALYHQFLRSSSPESELAGAFNKDLI
QNKSDINRLLERPYLPDGNANPQLTKCINLYKERFTRQAFDTCNEFLNSAGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAVQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPNDPRVSLLAGNLFNELNDPDAAIDAYKEGLSSSPDDMY
LTYNLAVSYFKKGEIPQAEEEFKKVVTKTPSGRLAALSYSYLGNIAYNKQDYKGAEYYFRQASALSPNEAKYLYNLAVVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDLDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYSEAITALSRVVDLNPKNAKAYHTLGLVYKHSGNGTLAIENWRKSIAIEP
ENIQSREALGDYLFENKFFREAVEEYIGVVKHKDDAYKVYLKMAEAYMGMQDDVNAEKILLKVLNTSKDGTDLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPEDMEGRLVLSKILIDSNSILDREKAIDELIAIVRSDVRPKIAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEESTRREGFF
>Mature_688_residues
MDKEIRKNRLFLEGIEEKELYFPEDQEPVRIRRSYNKLLIFWILMGLLVLGGLGFALYHQFLRSSSPESELAGAFNKDLI
QNKSDINRLLERPYLPDGNANPQLTKCINLYKERFTRQAFDTCNEFLNSAGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAVQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPNDPRVSLLAGNLFNELNDPDAAIDAYKEGLSSSPDDMY
LTYNLAVSYFKKGEIPQAEEEFKKVVTKTPSGRLAALSYSYLGNIAYNKQDYKGAEYYFRQASALSPNEAKYLYNLAVVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDLDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYSEAITALSRVVDLNPKNAKAYHTLGLVYKHSGNGTLAIENWRKSIAIEP
ENIQSREALGDYLFENKFFREAVEEYIGVVKHKDDAYKVYLKMAEAYMGMQDDVNAEKILLKVLNTSKDGTDLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPEDMEGRLVLSKILIDSNSILDREKAIDELIAIVRSDVRPKIAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEESTRREGFF

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=425, Percent_Identity=24.7058823529412, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI32307150, Length=429, Percent_Identity=24.7086247086247, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI301336134, Length=315, Percent_Identity=24.7619047619048, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI83415184, Length=315, Percent_Identity=24.7619047619048, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=425, Percent_Identity=24.9411764705882, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115532690, Length=425, Percent_Identity=24.9411764705882, Blast_Score=96, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6319589, Length=336, Percent_Identity=23.5119047619048, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647755, Length=431, Percent_Identity=24.1299303944316, Blast_Score=93, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24585827, Length=431, Percent_Identity=24.1299303944316, Blast_Score=93, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24585829, Length=431, Percent_Identity=24.1299303944316, Blast_Score=93, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19920486, Length=320, Percent_Identity=24.375, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076610, Length=320, Percent_Identity=24.375, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17137540, Length=509, Percent_Identity=19.2534381139489, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 78012; Mature: 78012

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS00496 PII_GLNB_UMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEIRKNRLFLEGIEEKELYFPEDQEPVRIRRSYNKLLIFWILMGLLVLGGLGFALYHQ
CCCHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLRSSSPESELAGAFNKDLIQNKSDINRLLERPYLPDGNANPQLTKCINLYKERFTRQAF
HHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTCNEFLNSAGTQEEKSIALTVLGVIHDESGRYPQAIERLQKAVQYDPKNFYAYYNLTLS
HHHHHHHHCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
YKHAGRFADARMAALKAKEIAPNDPRVSLLAGNLFNELNDPDAAIDAYKEGLSSSPDDMY
ECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHCCCCCCCEE
LTYNLAVSYFKKGEIPQAEEEFKKVVTKTPSGRLAALSYSYLGNIAYNKQDYKGAEYYFR
EEEHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCHHCCCCCCCCHHHHHH
QASALSPNEAKYLYNLAVVLQKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQG
HHCCCCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EMSISALQKSLKYNPTDLDSLFQLAEAYYNKGDLLSAEETYRRIVSSTPGDSFTETALIN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LGVVLDQMERYSEAITALSRVVDLNPKNAKAYHTLGLVYKHSGNGTLAIENWRKSIAIEP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCEECCC
ENIQSREALGDYLFENKFFREAVEEYIGVVKHKDDAYKVYLKMAEAYMGMQDDVNAEKIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LKVLNTSKDGTDLKNAHKKLALLYNKSKDPDLKNRAKDEAFRSAHMDPEDMEGRLVLSKI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIDSNSILDREKAIDELIAIVRSDVRPKIAATAYNYLGICYYKNGEFKRAVRAFQSSIDL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCHHHHHHHHHHHHCCC
DPSLSEAYENKRAASAALEESTRREGFF
CCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKEIRKNRLFLEGIEEKELYFPEDQEPVRIRRSYNKLLIFWILMGLLVLGGLGFALYHQ
CCCHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLRSSSPESELAGAFNKDLIQNKSDINRLLERPYLPDGNANPQLTKCINLYKERFTRQAF
HHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTCNEFLNSAGTQEEKSIALTVLGVIHDESGRYPQAIERLQKAVQYDPKNFYAYYNLTLS
HHHHHHHHCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
YKHAGRFADARMAALKAKEIAPNDPRVSLLAGNLFNELNDPDAAIDAYKEGLSSSPDDMY
ECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHCCCCCCCEE
LTYNLAVSYFKKGEIPQAEEEFKKVVTKTPSGRLAALSYSYLGNIAYNKQDYKGAEYYFR
EEEHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCHHCCCCCCCCHHHHHH
QASALSPNEAKYLYNLAVVLQKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQG
HHCCCCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EMSISALQKSLKYNPTDLDSLFQLAEAYYNKGDLLSAEETYRRIVSSTPGDSFTETALIN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LGVVLDQMERYSEAITALSRVVDLNPKNAKAYHTLGLVYKHSGNGTLAIENWRKSIAIEP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCEECCC
ENIQSREALGDYLFENKFFREAVEEYIGVVKHKDDAYKVYLKMAEAYMGMQDDVNAEKIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LKVLNTSKDGTDLKNAHKKLALLYNKSKDPDLKNRAKDEAFRSAHMDPEDMEGRLVLSKI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIDSNSILDREKAIDELIAIVRSDVRPKIAATAYNYLGICYYKNGEFKRAVRAFQSSIDL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCHHHHHHHHHHHHCCC
DPSLSEAYENKRAASAALEESTRREGFF
CCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105307 [H]