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The map label for this gene is thrC [H]

Identifier: 116327367

GI number: 116327367

Start: 623626

End: 624969

Strand: Direct

Name: thrC [H]

Synonym: LBL_0563

Alternate gene names: 116327367

Gene position: 623626-624969 (Clockwise)

Preceding gene: 116327366

Following gene: 116327368

Centisome position: 17.25

GC content: 45.24

Gene sequence:

>1344_bases
ATGATCTCCACTCTTACCCGGTACAAAGCGGAATTTGAATGTATTAACGACTCTTGCAAAACTCGGTACGATCTGAACGA
GATCGTCTACGAATGTAAAAAATGCGGAAGTCTTCTCCAAGTATCACATGACTTGGAGGCGTTGAGAACCGTATCGGGAA
AAGAGTGGAAAGATCGATTCGATTCCAGATTTCGTTCCGTAAAGTTTCCGAATTCTTCCGGAATTTGGAATAAAAGAGAA
TGGGTTCTTCCTCATATCGAAGATAAGAATATCGTAACCTCCGGGGAAGGGCTCACTCATCTTTTTACTTCCGATCGATT
GACTGAAAGTCTCGGGCTCGGAAATTTTTACGTAAAACAATGCGGGATTTCGCACACGGGTTCGTTCAAAGATCTCGGAA
TGACCGTTTTATTATCCCAAGTAAAACATATGATCACGTCCGGCGTTCCGATTCATGCGGTGGCTTGTGCAAGTTCCGGA
GATACTTCCGCTGCACTTGCGTCTTACGCGGCAAAGGCGGGAATACCAGCGATTATATTTTTGCCTGCGGGAAAGGTATC
GCAAGCGCAGTTGATCCAGCCGGTATCGAACGGAGCCAAGGTAATCGCACTCGACACGGATTTTGACGGATGTATGCAAA
TTGTCAAAGAAGTGACGAGGGAAGCGGGAATTTATCTTGCAAACTCGATGAATTCTTTACGGATCGAAGGACAAAAAACG
ATTTCCGTTGAAATTGTGCAACAGTTGGAATGGAAGGTTCCGGATTGGATCGTGATTCCGGGAGGCAATCTTGGAAACGT
ATCCGCGCTTGGAGCTGGATTTGAGATGATGTTTTCTTTGGGGCTTGTCGATAAACTTCCTAGGATCGCTTTAGCCCAAG
CGGAACATGCGAATCCGTTATATCTTTCTTACTTAAAGAATTTTGAAAGTTTCGAACCGGTTGTCGCTAAGACTACGCTT
GCGTCCGCGATTCAAATCGGAAATCCGGTTTCCATCCAAAAGGCGATTAAAACTCTCAAGAAGTTCAATGGAGTCGTGGA
ACAGGCTAATGAGTCGGAATTGGCGAATGCGGCAGCAAAGGCGGACTTATTCGGTTTATACAATGATCCTCATACGGGAG
TGGCTCTGGCGACTTTGGAAAAGCTGATCCAAAAAGGAACGATCGCTAAAGGGGAGAGTGTGGTCGTTATTTCGACCGCT
CACGGATTGAAGTTCACCGAATTCAAACTTCAGTTCCACGACGGAAAAATTCCGCAAGTAGATTCTACGGTCGTGAATTC
CATTCATCGAATTGAACCGAATGCGACAAAAGTCATCGACTTAATCCGGAAATTGTTGTTCTAG

Upstream 100 bases:

>100_bases
GGCAAGGATTGCGAAGTTGAAATCACTTCTCGACGGGGGACTGATCACACAAGAAGAATTTGATACCAAAAAAAAGGACA
TTTTGAATTCTATCTAAAAT

Downstream 100 bases:

>100_bases
GAGTAAGTTTTTGCATAAATCCGGATATTTTTTAAAACTATTTTAAAATTCTTTTTTTTGCCAAAAATAGGAAGTTTTTC
GTCAAATTTTTAATTCATGG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MISTLTRYKAEFECINDSCKTRYDLNEIVYECKKCGSLLQVSHDLEALRTVSGKEWKDRFDSRFRSVKFPNSSGIWNKRE
WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGNFYVKQCGISHTGSFKDLGMTVLLSQVKHMITSGVPIHAVACASSG
DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMQIVKEVTREAGIYLANSMNSLRIEGQKT
ISVEIVQQLEWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLVDKLPRIALAQAEHANPLYLSYLKNFESFEPVVAKTTL
ASAIQIGNPVSIQKAIKTLKKFNGVVEQANESELANAAAKADLFGLYNDPHTGVALATLEKLIQKGTIAKGESVVVISTA
HGLKFTEFKLQFHDGKIPQVDSTVVNSIHRIEPNATKVIDLIRKLLF

Sequences:

>Translated_447_residues
MISTLTRYKAEFECINDSCKTRYDLNEIVYECKKCGSLLQVSHDLEALRTVSGKEWKDRFDSRFRSVKFPNSSGIWNKRE
WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGNFYVKQCGISHTGSFKDLGMTVLLSQVKHMITSGVPIHAVACASSG
DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMQIVKEVTREAGIYLANSMNSLRIEGQKT
ISVEIVQQLEWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLVDKLPRIALAQAEHANPLYLSYLKNFESFEPVVAKTTL
ASAIQIGNPVSIQKAIKTLKKFNGVVEQANESELANAAAKADLFGLYNDPHTGVALATLEKLIQKGTIAKGESVVVISTA
HGLKFTEFKLQFHDGKIPQVDSTVVNSIHRIEPNATKVIDLIRKLLF
>Mature_447_residues
MISTLTRYKAEFECINDSCKTRYDLNEIVYECKKCGSLLQVSHDLEALRTVSGKEWKDRFDSRFRSVKFPNSSGIWNKRE
WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGNFYVKQCGISHTGSFKDLGMTVLLSQVKHMITSGVPIHAVACASSG
DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMQIVKEVTREAGIYLANSMNSLRIEGQKT
ISVEIVQQLEWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLVDKLPRIALAQAEHANPLYLSYLKNFESFEPVVAKTTL
ASAIQIGNPVSIQKAIKTLKKFNGVVEQANESELANAAAKADLFGLYNDPHTGVALATLEKLIQKGTIAKGESVVVISTA
HGLKFTEFKLQFHDGKIPQVDSTVVNSIHRIEPNATKVIDLIRKLLF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786185, Length=303, Percent_Identity=27.0627062706271, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 48769; Mature: 48769

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTLTRYKAEFECINDSCKTRYDLNEIVYECKKCGSLLQVSHDLEALRTVSGKEWKDRF
CCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
DSRFRSVKFPNSSGIWNKREWVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGNFYVKQ
HHHHHEEECCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEHHHHHHHHHHCCCHHHHHH
CGISHTGSFKDLGMTVLLSQVKHMITSGVPIHAVACASSGDTSAALASYAAKAGIPAIIF
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
LPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMQIVKEVTREAGIYLANSMNSLRIEGQKT
ECCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCE
ISVEIVQQLEWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLVDKLPRIALAQAEHANPL
EHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCH
YLSYLKNFESFEPVVAKTTLASAIQIGNPVSIQKAIKTLKKFNGVVEQANESELANAAAK
HHHHHHCCHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ADLFGLYNDPHTGVALATLEKLIQKGTIAKGESVVVISTAHGLKFTEFKLQFHDGKIPQV
HHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCC
DSTVVNSIHRIEPNATKVIDLIRKLLF
CHHHHHHHHHCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MISTLTRYKAEFECINDSCKTRYDLNEIVYECKKCGSLLQVSHDLEALRTVSGKEWKDRF
CCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
DSRFRSVKFPNSSGIWNKREWVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGNFYVKQ
HHHHHEEECCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEHHHHHHHHHHCCCHHHHHH
CGISHTGSFKDLGMTVLLSQVKHMITSGVPIHAVACASSGDTSAALASYAAKAGIPAIIF
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
LPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMQIVKEVTREAGIYLANSMNSLRIEGQKT
ECCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCE
ISVEIVQQLEWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLVDKLPRIALAQAEHANPL
EHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCH
YLSYLKNFESFEPVVAKTTLASAIQIGNPVSIQKAIKTLKKFNGVVEQANESELANAAAK
HHHHHHCCHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ADLFGLYNDPHTGVALATLEKLIQKGTIAKGESVVVISTAHGLKFTEFKLQFHDGKIPQV
HHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCC
DSTVVNSIHRIEPNATKVIDLIRKLLF
CHHHHHHHHHCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]