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The map label for this gene is adh [H]

Identifier: 116327355

GI number: 116327355

Start: 609408

End: 610829

Strand: Direct

Name: adh [H]

Synonym: LBL_0551

Alternate gene names: 116327355

Gene position: 609408-610829 (Clockwise)

Preceding gene: 116327354

Following gene: 116327356

Centisome position: 16.86

GC content: 44.09

Gene sequence:

>1422_bases
ATGAAAATTCAATTCTCAGCTATGGACTATCGTTCGGATGATACTTTTGAAAAGGCCGATTATGGGTTCGAAGGAAGTTT
GGAAAAAGGTTGGGACATTTTCAGAAACGGAAAAGAATATCTGCATCTAGGCCCGGGTTATAAACTTTTAAAATCTAAAC
TTTGTGGAGTTTGTTCCACGGATCTTTCCCGACGGTTTCTTCCATTTCCACTTCCGCAAGTAATCGGACACGAGGTTATC
GCCGAGGACGTAGAATTCCGCGACGGAATCAAACAAAAATACGTTGTAGAGATCAATGATACGTTTGAAGCAAGGGGAGA
AATTCCTTTCGATGAATTTTGTAAGGAAGGAATTCCGTCTCACAGTCCCGAAAGAAAAGTTTTAGGCATCGATCGATTGC
CCGGCGGATTTGGTCCTTATATATTGGCTCCTCAAAGTGCGGCGATTCCTTTTCGAAATCTTCCCGATAAAACAGCGGTT
TTGATCGAACCGTTCGCCGCTTCTTTACAAGCTGTGATCGCTTCTCCTCCTAAAAACGGAGACAACGTTGCGGTCCTAGG
TCCGAGGAGATTGGGAAGCCTTGTTGTATCTGCGTTAGTCGCTTTTAGGGAGTCTTCCGGAATCCGATTTAAGGTTTCCG
CTTTAGCGAGACACGATCATCTTTTAAAACTTTCTCTCGATCTAGGGGCGGATGAAGCCATCGACCTCCGAAAGGAAAGT
ATTAAGTCTCTCAAAGATCGTTTTGCGATCGTCTACGACACGACGAGTACTACATCCGGCTTTGAAAGTGCAATCCAACT
TTCAAATAGGGAGTTACATCTTAAAACCACGAACGGACAAAAAGTTTTCGGTGTAGAAAGGCTCACGGAGCTGGTCGTCG
ACGAATTATCCCTTTTGAAATTCACGGATGAAAATTTGGATTTTCATTGGGAAAAAGAAACTCGTTCCAATCGAACCGTT
TACGTTGCGCCTAATGTGGGAAATGTTTCTCTACCGTCCCGTTTCAGGGTATATTATGGAAGCGTTGAGGAAGCTGAAAA
AATCCTTCTTTCCAAGGATTTTAAAGGTCGCGTGCCCCGTTTCGATTTAGGAATCGCAGGAACTTCCGAGGAAATCGATC
TTTTGATTCGTCCGAATCGTCGTCACGAAAATTCTCTCGTTCGTCCGAGAAGTGCAATCCTTTTCAAAGGGGAACCTAAG
GGAAATGATCTATTAGAGTTTTTGAATGCCGGTAAATCGATTCGTTCTTCCCGATGTGGAGATTTTCATCTCGCCATCAA
ACTCCTGCAGGAAAACGGAAAAGTTTCGGAGGCTCTGGAGAAGAATATGGTGACTCATACGTATCCTCCGGAAAGTCTTT
CTCAGGCGTTTACAACCGCTCGTACACCGGAAGCGATCAAAGTAGTGATTGAACATGTCTGA

Upstream 100 bases:

>100_bases
ATGTTGTTCTTATACATCGTAGCATAATAATCCCTTTCGCATTTGTTATGCTGGACTCGTTAAGTTTGCCCGGATTTTTT
GTCTAACCAAGGGTGATGTA

Downstream 100 bases:

>100_bases
TTCCTCCACATTTAGGGAATTAGAAACTTCTCTTGGGCCGACTTTGAAAGGAGGTGGGGAAGGAATTTTGGAGCTCGATT
TAAGGAATCTTCGGATTTTC

Product: Zn-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: ADH [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKIQFSAMDYRSDDTFEKADYGFEGSLEKGWDIFRNGKEYLHLGPGYKLLKSKLCGVCSTDLSRRFLPFPLPQVIGHEVI
AEDVEFRDGIKQKYVVEINDTFEARGEIPFDEFCKEGIPSHSPERKVLGIDRLPGGFGPYILAPQSAAIPFRNLPDKTAV
LIEPFAASLQAVIASPPKNGDNVAVLGPRRLGSLVVSALVAFRESSGIRFKVSALARHDHLLKLSLDLGADEAIDLRKES
IKSLKDRFAIVYDTTSTTSGFESAIQLSNRELHLKTTNGQKVFGVERLTELVVDELSLLKFTDENLDFHWEKETRSNRTV
YVAPNVGNVSLPSRFRVYYGSVEEAEKILLSKDFKGRVPRFDLGIAGTSEEIDLLIRPNRRHENSLVRPRSAILFKGEPK
GNDLLEFLNAGKSIRSSRCGDFHLAIKLLQENGKVSEALEKNMVTHTYPPESLSQAFTTARTPEAIKVVIEHV

Sequences:

>Translated_473_residues
MKIQFSAMDYRSDDTFEKADYGFEGSLEKGWDIFRNGKEYLHLGPGYKLLKSKLCGVCSTDLSRRFLPFPLPQVIGHEVI
AEDVEFRDGIKQKYVVEINDTFEARGEIPFDEFCKEGIPSHSPERKVLGIDRLPGGFGPYILAPQSAAIPFRNLPDKTAV
LIEPFAASLQAVIASPPKNGDNVAVLGPRRLGSLVVSALVAFRESSGIRFKVSALARHDHLLKLSLDLGADEAIDLRKES
IKSLKDRFAIVYDTTSTTSGFESAIQLSNRELHLKTTNGQKVFGVERLTELVVDELSLLKFTDENLDFHWEKETRSNRTV
YVAPNVGNVSLPSRFRVYYGSVEEAEKILLSKDFKGRVPRFDLGIAGTSEEIDLLIRPNRRHENSLVRPRSAILFKGEPK
GNDLLEFLNAGKSIRSSRCGDFHLAIKLLQENGKVSEALEKNMVTHTYPPESLSQAFTTARTPEAIKVVIEHV
>Mature_473_residues
MKIQFSAMDYRSDDTFEKADYGFEGSLEKGWDIFRNGKEYLHLGPGYKLLKSKLCGVCSTDLSRRFLPFPLPQVIGHEVI
AEDVEFRDGIKQKYVVEINDTFEARGEIPFDEFCKEGIPSHSPERKVLGIDRLPGGFGPYILAPQSAAIPFRNLPDKTAV
LIEPFAASLQAVIASPPKNGDNVAVLGPRRLGSLVVSALVAFRESSGIRFKVSALARHDHLLKLSLDLGADEAIDLRKES
IKSLKDRFAIVYDTTSTTSGFESAIQLSNRELHLKTTNGQKVFGVERLTELVVDELSLLKFTDENLDFHWEKETRSNRTV
YVAPNVGNVSLPSRFRVYYGSVEEAEKILLSKDFKGRVPRFDLGIAGTSEEIDLLIRPNRRHENSLVRPRSAILFKGEPK
GNDLLEFLNAGKSIRSSRCGDFHLAIKLLQENGKVSEALEKNMVTHTYPPESLSQAFTTARTPEAIKVVIEHV

Specific function: Active with primary alcohols, including methanol [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 52866; Mature: 52866

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQFSAMDYRSDDTFEKADYGFEGSLEKGWDIFRNGKEYLHLGPGYKLLKSKLCGVCST
CEEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHH
DLSRRFLPFPLPQVIGHEVIAEDVEFRDGIKQKYVVEINDTFEARGEIPFDEFCKEGIPS
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCC
HSPERKVLGIDRLPGGFGPYILAPQSAAIPFRNLPDKTAVLIEPFAASLQAVIASPPKNG
CCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCC
DNVAVLGPRRLGSLVVSALVAFRESSGIRFKVSALARHDHLLKLSLDLGADEAIDLRKES
CCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCCCHHHHHHHHH
IKSLKDRFAIVYDTTSTTSGFESAIQLSNRELHLKTTNGQKVFGVERLTELVVDELSLLK
HHHHHHCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHE
FTDENLDFHWEKETRSNRTVYVAPNVGNVSLPSRFRVYYGSVEEAEKILLSKDFKGRVPR
EECCCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCE
FDLGIAGTSEEIDLLIRPNRRHENSLVRPRSAILFKGEPKGNDLLEFLNAGKSIRSSRCG
EEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHCCCC
DFHLAIKLLQENGKVSEALEKNMVTHTYPPESLSQAFTTARTPEAIKVVIEHV
CHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MKIQFSAMDYRSDDTFEKADYGFEGSLEKGWDIFRNGKEYLHLGPGYKLLKSKLCGVCST
CEEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHH
DLSRRFLPFPLPQVIGHEVIAEDVEFRDGIKQKYVVEINDTFEARGEIPFDEFCKEGIPS
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCC
HSPERKVLGIDRLPGGFGPYILAPQSAAIPFRNLPDKTAVLIEPFAASLQAVIASPPKNG
CCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCC
DNVAVLGPRRLGSLVVSALVAFRESSGIRFKVSALARHDHLLKLSLDLGADEAIDLRKES
CCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCCCHHHHHHHHH
IKSLKDRFAIVYDTTSTTSGFESAIQLSNRELHLKTTNGQKVFGVERLTELVVDELSLLK
HHHHHHCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHE
FTDENLDFHWEKETRSNRTVYVAPNVGNVSLPSRFRVYYGSVEEAEKILLSKDFKGRVPR
EECCCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCE
FDLGIAGTSEEIDLLIRPNRRHENSLVRPRSAILFKGEPKGNDLLEFLNAGKSIRSSRCG
EEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHCCCC
DFHLAIKLLQENGKVSEALEKNMVTHTYPPESLSQAFTTARTPEAIKVVIEHV
CHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8049268 [H]