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The map label for this gene is ptsJ [H]

Identifier: 116248950

GI number: 116248950

Start: 297597

End: 298982

Strand: Direct

Name: ptsJ [H]

Synonym: pRL120281

Alternate gene names: 116248950

Gene position: 297597-298982 (Clockwise)

Preceding gene: 116248947

Following gene: 116248953

Centisome position: 34.21

GC content: 62.84

Gene sequence:

>1386_bases
GTGCAAGCTCCAAATGCGACGCGGTCAAGCTGGGCGATCGGGACTTCAGGCGTCATCCTGGGGCGACACGGTCGAAGCCT
CCTGGTTTGCCGAAAAAATAGCCGACCGCAGCATCCGGGGGATCGCTCTCGAAACGAGCGCGCTGATCCGTGCCGGTGTC
CTGCCCATTGGGACGCGCCTGCCGGCGATCCGCGATATCGCTTACGAATTGCATGTCAGTCCGGCAACGATCTCCGAAGT
GGCGAGACGTTCCGGCTTGGCGACAAAGCGGTCGCCGCTGACCCAGGTGCCGTTGCGCCCCCGGCCGCTGATGATCTTTT
GCCGCCGCAATTCACTCCAGGCAGCTCGGGAAATTATGCGGCAGGTGTGCTCGACCTCACCTTAGCCGGACCGGATGCCG
CACTTCTTCCCCGCCTCGCCGAAGCCATGGCCTATGGCGCGTCCGTCGATGACCTCAACAGCTATGAGCGCAGCCGGATC
GTACCAGAGTTGAAAGACGCCGTTTCAGAGCGATGGCCTTATGAGGCGGAAGCCTTTCTGGCCACCAATGGCGGTTACAA
CGCCGTCTATACGATATTGCATGCGCTGGTCTCCTCGGGCTCGTCGGTCGCGATCGAACATCCGACCGCGATGCGGCTGC
TCGATATTCTGGAAGATCTCGGCGTGAAAATCATCCCTGTCGCCTGCGACGGCGAAGGCCCCCTGCCGGATTCGCTGCGC
GAAGCATTGCAGCAACGTCCGGCAGCTTTCCTGTTCCAGCCGCGGCTGCATTCCGTGACCGGCGTTACGGTCAGTTCATC
CCGCCTCGATCAGCTCGGCGATGTGCTGGAAGACAGCGATACGCTTATCATCGAGGATGACGGCGTCGGCGACGTGTCGG
CGGCACCTCCGCAGTCGCTGGGCGGCCGATTTGCGGAGCGGACGATCCATATCCTCTCACTCTCGAAAAGCCTCGGCCCG
GATCTGCGTCTCGCGGTTCTGTCGAGTTCCGCGCCGATCGTCGACCAGATCCAGTCTTACCGTTCCTTCAGCGCCGGCTG
GACGAGCCGTATCCTGCAAGGTGCCGCGGCCTGGCTATTGCGCGATCCGGCAAGCTGGCAGCTTATCGGCGAGGCGCGCG
AGATCTATCAGCAGAGACGCGACGCTCTTGCCGATGCGCTCAGCGAACGGGGAATACCGATACCGCCGGGTCAGGGCCTG
TGCCTCTGGGTGCCCGTCGTCTCCGAACCATTCGCGATGGTGACGCTCGCCGCACGCAATATCGCCGTCAATCCAGGCAG
CAAATTCTCCGTCCTGCCGAGCAGTCATATCCGTGTCGCGACCAGCACGCTCAGCCATCGCTGCGAGGAAGCCGCCGATG
CGATTGCGCTGGCTCATACGCCGTGA

Upstream 100 bases:

>100_bases
GCCGGCGTCGTTATAGTTGGCAATCATGCTGCGCATCCTGGATTGCGGCGAGAGGTGTTGACGTGATGGTCTCGCTACAA
AATCCTTTGCGCTACAGAAA

Downstream 100 bases:

>100_bases
AAAGCAGGGCCGCAGCCCGTGTCTCTGATCCCCAGTTTGTCCGAGCAAGTCCGGAAACTACTTTCCCTCAAGCCATTCCT
GCAGCTCTGCCTCAGCCCGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQAPNATRSSWAIGTSGVILGRHGRSLLVCRKNSRPQHPGDRSRNERADPCRCPAHWDAPAGDPRYRLRIACQSGNDLRS
GETFRLGDKAVAADPGAVAPPAADDLLPPQFTPGSSGNYAAGVLDLTLAGPDAALLPRLAEAMAYGASVDDLNSYERSRI
VPELKDAVSERWPYEAEAFLATNGGYNAVYTILHALVSSGSSVAIEHPTAMRLLDILEDLGVKIIPVACDGEGPLPDSLR
EALQQRPAAFLFQPRLHSVTGVTVSSSRLDQLGDVLEDSDTLIIEDDGVGDVSAAPPQSLGGRFAERTIHILSLSKSLGP
DLRLAVLSSSAPIVDQIQSYRSFSAGWTSRILQGAAAWLLRDPASWQLIGEAREIYQQRRDALADALSERGIPIPPGQGL
CLWVPVVSEPFAMVTLAARNIAVNPGSKFSVLPSSHIRVATSTLSHRCEEAADAIALAHTP

Sequences:

>Translated_461_residues
MQAPNATRSSWAIGTSGVILGRHGRSLLVCRKNSRPQHPGDRSRNERADPCRCPAHWDAPAGDPRYRLRIACQSGNDLRS
GETFRLGDKAVAADPGAVAPPAADDLLPPQFTPGSSGNYAAGVLDLTLAGPDAALLPRLAEAMAYGASVDDLNSYERSRI
VPELKDAVSERWPYEAEAFLATNGGYNAVYTILHALVSSGSSVAIEHPTAMRLLDILEDLGVKIIPVACDGEGPLPDSLR
EALQQRPAAFLFQPRLHSVTGVTVSSSRLDQLGDVLEDSDTLIIEDDGVGDVSAAPPQSLGGRFAERTIHILSLSKSLGP
DLRLAVLSSSAPIVDQIQSYRSFSAGWTSRILQGAAAWLLRDPASWQLIGEAREIYQQRRDALADALSERGIPIPPGQGL
CLWVPVVSEPFAMVTLAARNIAVNPGSKFSVLPSSHIRVATSTLSHRCEEAADAIALAHTP
>Mature_461_residues
MQAPNATRSSWAIGTSGVILGRHGRSLLVCRKNSRPQHPGDRSRNERADPCRCPAHWDAPAGDPRYRLRIACQSGNDLRS
GETFRLGDKAVAADPGAVAPPAADDLLPPQFTPGSSGNYAAGVLDLTLAGPDAALLPRLAEAMAYGASVDDLNSYERSRI
VPELKDAVSERWPYEAEAFLATNGGYNAVYTILHALVSSGSSVAIEHPTAMRLLDILEDLGVKIIPVACDGEGPLPDSLR
EALQQRPAAFLFQPRLHSVTGVTVSSSRLDQLGDVLEDSDTLIIEDDGVGDVSAAPPQSLGGRFAERTIHILSLSKSLGP
DLRLAVLSSSAPIVDQIQSYRSFSAGWTSRILQGAAAWLLRDPASWQLIGEAREIYQQRRDALADALSERGIPIPPGQGL
CLWVPVVSEPFAMVTLAARNIAVNPGSKFSVLPSSHIRVATSTLSHRCEEAADAIALAHTP

Specific function: Putative transcriptional regulator of the ptsHI/crr operon [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=297, Percent_Identity=24.9158249158249, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI33469970, Length=297, Percent_Identity=24.9158249158249, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790797, Length=276, Percent_Identity=26.8115942028986, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 49140; Mature: 49140

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAPNATRSSWAIGTSGVILGRHGRSLLVCRKNSRPQHPGDRSRNERADPCRCPAHWDAP
CCCCCCCCCCEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGDPRYRLRIACQSGNDLRSGETFRLGDKAVAADPGAVAPPAADDLLPPQFTPGSSGNYA
CCCCCEEEEEEECCCCCCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
AGVLDLTLAGPDAALLPRLAEAMAYGASVDDLNSYERSRIVPELKDAVSERWPYEAEAFL
EEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
ATNGGYNAVYTILHALVSSGSSVAIEHPTAMRLLDILEDLGVKIIPVACDGEGPLPDSLR
EECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
EALQQRPAAFLFQPRLHSVTGVTVSSSRLDQLGDVLEDSDTLIIEDDGVGDVSAAPPQSL
HHHHHCCCEEEECCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHH
GGRFAERTIHILSLSKSLGPDLRLAVLSSSAPIVDQIQSYRSFSAGWTSRILQGAAAWLL
CCHHHHHEEEEEEEHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RDPASWQLIGEAREIYQQRRDALADALSERGIPIPPGQGLCLWVPVVSEPFAMVTLAARN
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCE
IAVNPGSKFSVLPSSHIRVATSTLSHRCEEAADAIALAHTP
EEECCCCCEEECCCCCEEEHHHHHHHHHHHHHHHEEEECCC
>Mature Secondary Structure
MQAPNATRSSWAIGTSGVILGRHGRSLLVCRKNSRPQHPGDRSRNERADPCRCPAHWDAP
CCCCCCCCCCEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGDPRYRLRIACQSGNDLRSGETFRLGDKAVAADPGAVAPPAADDLLPPQFTPGSSGNYA
CCCCCEEEEEEECCCCCCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
AGVLDLTLAGPDAALLPRLAEAMAYGASVDDLNSYERSRIVPELKDAVSERWPYEAEAFL
EEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
ATNGGYNAVYTILHALVSSGSSVAIEHPTAMRLLDILEDLGVKIIPVACDGEGPLPDSLR
EECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
EALQQRPAAFLFQPRLHSVTGVTVSSSRLDQLGDVLEDSDTLIIEDDGVGDVSAAPPQSL
HHHHHCCCEEEECCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHH
GGRFAERTIHILSLSKSLGPDLRLAVLSSSAPIVDQIQSYRSFSAGWTSRILQGAAAWLL
CCHHHHHEEEEEEEHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RDPASWQLIGEAREIYQQRRDALADALSERGIPIPPGQGLCLWVPVVSEPFAMVTLAARN
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCE
IAVNPGSKFSVLPSSHIRVATSTLSHRCEEAADAIALAHTP
EEECCCCCEEECCCCCEEEHHHHHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7612925; 11677609 [H]