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The map label for this gene is ade

Identifier: 11496787

GI number: 11496787

Start: 10301

End: 11947

Strand: Direct

Name: ade

Synonym: BBK17

Alternate gene names: 11496787

Gene position: 10301-11947 (Clockwise)

Preceding gene: 11496781

Following gene: 11496820

Centisome position: 27.95

GC content: 30.24

Gene sequence:

>1647_bases
ATGGATTTATTTAAAATTGAAGCTAATTATATTGACATCTTTAATAAAGAAATTTATCCAGCTAGTATAGCGATTGCAAA
CGGTCATATTGCGAGCATAGAAAAAATTAATGCGACATTGGATGAATATGTGCTGCCAGGATTTATTGATGCGCATATAC
ATATAGAGAGTTCTTTTCTTGTTCCATCAAACTTTGCTCATTTAGTAGTTGCACACGGCACTGTGGCTACAATAAGCGAT
CCTCATGAAATAGCCAATGTTAATGGTATTGATGGCATCAATTTTATGATAAATAATTCTAAAAAAACCGAGTTTAAATT
TTTTTTTGGAGCTCCTTCTTGTGTGCCAGCGTTGTCACAAGAATTTGAAACTTCAGGATATGTATTAAATGATAAAGATA
TAGATGAATTGATGAAATTAGATGATATTTACTATTTGGCTGAAGTAATGGATTTTAAAGGCGTGATTAACAAAGATATT
GAAATTATAAATAAAATAAATTCTGCATTAAAGCGTAATAAGGTTGTTGATGGGCATGCTCCTGGTTTGTCCCCCAATTT
AACTTTAAAGTATGCATCTTCAGGCATTAGCACTGATCATGAATGTTTAACAATAGAAGATGCAAGATATAAATTATCTT
TGGGCATGAAAATACTAATTAGAGAAGGAAGTGCCGCTAAAAATTTTGAATCTTTGCATCCTTTGATTAGTGAATGTTCT
AAAAAATATTGTGATTCCTTAATGTTTTGTTTTGATGATGCACACCCAAATGACATTCTAAATGGACATATTAATTTAAT
AGTAGCTCGTGCAATAAAGCATGGGCACGACTTTTTTGATGTTTTGAAAATAGCATGCATTAATCCGGTTTTACACTATA
AAATCCCAGTGGGGTTGTTAAGAATAGGAGATCCTGCTGATTTTATAATTACAAAAGATATCAAAACATTCAAAATAAAT
AAAACCTACATTAATGGTAAATTGGTTTTTAATGATGGAATTTCACTTATCCCATTAATAAATGAAATTCCTATAAACAA
TTTTAATTGTAGCAAAAAATCTATTTCGGATTTTAAATTTTCCACTAAAAATAAGATGATCCCAGTAATCAAATGCATCA
GCAACCAAATTATTACTCATAAAACTATGATTGATAGCAATTTATTGGCCCCAGATTTTCAATCTAATATTGCCGAGGAT
ATTTTAAAAATAGCTATAATAAATCGATATAAAGACAATAGTAAAATTTCTATAGGATTTATAAAAAATTTTGGAATAAG
AAACGGCGCCATAGGAAGTACAGTTGCTCATGATTCTCACAACATCATACTTGTTGGAAGCAATGATGAATATTTGTGTA
AAGCGGCAAATACAATCATCCAGAATAAGGGGGGTTTATGTGCACTAAACAATGAAAAAACTATAATAATGGAACTTCCT
ATTTCTGGATTAATGAGTACTCTTTCAGCCGAAAGAGTAGCTTCACAATATATAAAATTAAATGATTTTTGTAAAAATGT
TTTAGGCTCTCGGCTTGATGATCCTCTAATGACTTTGTCTTTTATGTCTTTAACGGTGGTTCCCCATTTAAAGATAAATG
ATAAAGGACTGTTTGATGTTGATTCTTTTTGTTTTGTAGATTATTAA

Upstream 100 bases:

>100_bases
GTTGCAATTAAATATACTGGCACTTTGCGCTATAATTTAAGTTTAAAGATTTTAAGGTAGAGTATATTATGAACAAAAAG
TTTTTAGGAGAGGATAAATA

Downstream 100 bases:

>100_bases
TTTTAAATTATTATAAAAAGGCAAAAAAAGATTAAAAAATTAAGCGATAAAATTGTAGAAGGAACTCAAAAGTTTTTTGT
CTGTTATTATCTATTAAGGA

Product: adenine deaminase (adeC)

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFLVPSNFAHLVVAHGTVATISD
PHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDI
EIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECS
KKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLLRIGDPADFIITKDIKTFKIN
KTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELP
ISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY

Sequences:

>Translated_548_residues
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFLVPSNFAHLVVAHGTVATISD
PHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDI
EIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECS
KKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLLRIGDPADFIITKDIKTFKIN
KTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELP
ISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY
>Mature_548_residues
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFLVPSNFAHLVVAHGTVATISD
PHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDI
EIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECS
KKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLLRIGDPADFIITKDIKTFKIN
KTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELP
ISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=545, Percent_Identity=32.4770642201835, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_BORBU (O50821)

Other databases:

- EMBL:   AE000788
- PIR:   C70253
- RefSeq:   NP_045591.1
- ProteinModelPortal:   O50821
- EnsemblBacteria:   EBBORT00000009408
- GeneID:   1194225
- GenomeReviews:   AE000788_GR
- KEGG:   bbu:BBK17
- NMPDR:   fig|224326.1.peg.1442
- TIGR:   BB_K17
- GeneTree:   EBGT00050000006788
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- PhylomeDB:   O50821
- ProtClustDB:   CLSK862557
- BioCyc:   BBUR224326:BB_K17-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 60865; Mature: 60865

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFL
CCEEEEECCEEEEECCCCCCEEEEEECCCEEEHHHHHCCHHHHCCCCEEEEEEEEEEEEE
VPSNFAHLVVAHGTVATISDPHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQ
CCCCCEEEEEECCEEEECCCCHHHCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHH
EFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDIEIINKINSALKRNKVVDGHA
HHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECS
CCCCCCEEEEEECCCCCCCCCEEEEECCEEEEECCEEEEEECCCCCCCHHHHHHHHHHHH
KKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLL
HHHHHHHEEEECCCCCCCCCCCHHHHEEEHHHHCCCHHHHHHHHHHHCCCEEEECCEEEE
RIGDPADFIITKDIKTFKINKTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKF
EECCCCCEEEECCCEEEEEEEEEEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCEE
STKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAEDILKIAIINRYKDNSKISIGF
CCCCCCHHHHHHHCCCCEEEHEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELP
EECCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECC
ISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEEEEECCCCCEEC
DSFCFVDY
CCEEEECC
>Mature Secondary Structure
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFL
CCEEEEECCEEEEECCCCCCEEEEEECCCEEEHHHHHCCHHHHCCCCEEEEEEEEEEEEE
VPSNFAHLVVAHGTVATISDPHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQ
CCCCCEEEEEECCEEEECCCCHHHCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHH
EFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDIEIINKINSALKRNKVVDGHA
HHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECS
CCCCCCEEEEEECCCCCCCCCEEEEECCEEEEECCEEEEEECCCCCCCHHHHHHHHHHHH
KKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLL
HHHHHHHEEEECCCCCCCCCCCHHHHEEEHHHHCCCHHHHHHHHHHHCCCEEEECCEEEE
RIGDPADFIITKDIKTFKINKTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKF
EECCCCCEEEECCCEEEEEEEEEEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCEE
STKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAEDILKIAIINRYKDNSKISIGF
CCCCCCHHHHHHHCCCCEEEHEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELP
EECCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECC
ISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEEEEECCCCCEEC
DSFCFVDY
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685