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The map label for this gene is aspC [H]

Identifier: 114800411

GI number: 114800411

Start: 655476

End: 656666

Strand: Direct

Name: aspC [H]

Synonym: HNE_0652

Alternate gene names: 114800411

Gene position: 655476-656666 (Clockwise)

Preceding gene: 114798400

Following gene: 114800409

Centisome position: 17.69

GC content: 63.81

Gene sequence:

>1191_bases
ATGTCTCATTTCTCGCCCCTCTCCACGCTCCCGCCGGATGCGCTCCTCGGGCTCATGACGGCATACCGCGCCGATGAGCG
CAGTGAAAAATTCGATCTCGGCGTCGGTGTCTACAAGGACGAGAATGGCGAAACCCCGATCCTCTCGGCGGTGCGCAAGG
CCGAGGCCAAGATGCTCGCGGCGCAGACCACGAAGGTCTACGAAGGCCCGCGCGGCAATACCGATTTCTGCGCCCATATC
GAAAAGTTCGTGTTCGGCAAGGACCATCCGGCGCTGGCCGAAAACCGCGTCCTCTCCTTCACGTCTCCGGGTGGCTGCGG
CGCGCTCTTTCTCGGCGTCGGCCTGATGCGCCGCATGGGCACGCGCCGCGTCTGGGTCTCGCGGCCCACTTGGCCAAACC
ACCCCAACGTCGTCAAATCCCTGGGCCTGGACGTGAAGGAATACACCTATTCGCGTGACGGCGCCTTCTACCGTCTCGGC
GCGCTGGCTGACCTCTCGACCGCAGAGCGTGGCGATGGCATCATCATCCAGGGCCCCTGCCACAACCCCACCGGAATCGA
TCCGTCAACGGAAGACTGGCGCGAGCTTGGAAAGCTCTGCAAGGATAAGGGCATCATCGCGCTGCTCGATGTCGCCTATC
ACGGCTTCGCCTCGGGCCTTGACCGGGACATGGACGGCGTGCGCGCCTTCATTGATGAGGCGGGCGAGGCACTGATCTCC
TATTCCTGCTCGAAGAACTTTGGTCTCTACCGGGAACGCACGGGCTGCTTCCTCGCCGTTGGCGCAGAAGCAGAAGGCAT
CGCGGCGGCCACCACGCATGTGGCCGATATGGGCCGCGCGACCTGGTCTATGCCGCCGTCGCATGGCGCAGGCATCGTCG
CCACCATTCTGGACGATCCGGACCTGCGCGCCGAATGGGAGACGGAGCTTTCCGCCATGCGCACACGGATGATCGGTCTG
CGCGAAGCGCTCTCTGACGCCCTCGTCAGCCATTCGGGATCAAACCTGCTGGCGGCCCTCAAGACGCAGAACGGCATGTT
CTCCCAACTGCCGATCTCGGCCGAAGACACCGCCAAGGCCCGCGAAGCAGACGGCATCTACATGCCGTCTTCCGGCCGCA
TCAATATCGCCGGGCTTCACCCAAGTGACATTCCGCGCCTCGCGGAAATCCTGGCGGGCTATCTGGTCTAG

Upstream 100 bases:

>100_bases
AATGGCATAGACTTCGCGCAACGATCCCAGTGCGCGGGGTTTATTATGCGGCGGAAAGCCGATACGGGTCACCGCGAAAG
AAACGGAAGGCCCTCTCCTC

Downstream 100 bases:

>100_bases
ACACCCCATTCATCCCCGCCTTCGCGGGGATGAACGGAAATTTCAGACTTACACGCCCTCAACAAAAATAACCCGGTAAT
CTGCCGCCTGATAGCGGTGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSHFSPLSTLPPDALLGLMTAYRADERSEKFDLGVGVYKDENGETPILSAVRKAEAKMLAAQTTKVYEGPRGNTDFCAHI
EKFVFGKDHPALAENRVLSFTSPGGCGALFLGVGLMRRMGTRRVWVSRPTWPNHPNVVKSLGLDVKEYTYSRDGAFYRLG
ALADLSTAERGDGIIIQGPCHNPTGIDPSTEDWRELGKLCKDKGIIALLDVAYHGFASGLDRDMDGVRAFIDEAGEALIS
YSCSKNFGLYRERTGCFLAVGAEAEGIAAATTHVADMGRATWSMPPSHGAGIVATILDDPDLRAEWETELSAMRTRMIGL
REALSDALVSHSGSNLLAALKTQNGMFSQLPISAEDTAKAREADGIYMPSSGRINIAGLHPSDIPRLAEILAGYLV

Sequences:

>Translated_396_residues
MSHFSPLSTLPPDALLGLMTAYRADERSEKFDLGVGVYKDENGETPILSAVRKAEAKMLAAQTTKVYEGPRGNTDFCAHI
EKFVFGKDHPALAENRVLSFTSPGGCGALFLGVGLMRRMGTRRVWVSRPTWPNHPNVVKSLGLDVKEYTYSRDGAFYRLG
ALADLSTAERGDGIIIQGPCHNPTGIDPSTEDWRELGKLCKDKGIIALLDVAYHGFASGLDRDMDGVRAFIDEAGEALIS
YSCSKNFGLYRERTGCFLAVGAEAEGIAAATTHVADMGRATWSMPPSHGAGIVATILDDPDLRAEWETELSAMRTRMIGL
REALSDALVSHSGSNLLAALKTQNGMFSQLPISAEDTAKAREADGIYMPSSGRINIAGLHPSDIPRLAEILAGYLV
>Mature_395_residues
SHFSPLSTLPPDALLGLMTAYRADERSEKFDLGVGVYKDENGETPILSAVRKAEAKMLAAQTTKVYEGPRGNTDFCAHIE
KFVFGKDHPALAENRVLSFTSPGGCGALFLGVGLMRRMGTRRVWVSRPTWPNHPNVVKSLGLDVKEYTYSRDGAFYRLGA
LADLSTAERGDGIIIQGPCHNPTGIDPSTEDWRELGKLCKDKGIIALLDVAYHGFASGLDRDMDGVRAFIDEAGEALISY
SCSKNFGLYRERTGCFLAVGAEAEGIAAATTHVADMGRATWSMPPSHGAGIVATILDDPDLRAEWETELSAMRTRMIGLR
EALSDALVSHSGSNLLAALKTQNGMFSQLPISAEDTAKAREADGIYMPSSGRINIAGLHPSDIPRLAEILAGYLV

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=386, Percent_Identity=33.9378238341969, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI4504067, Length=398, Percent_Identity=33.6683417085427, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI117414139, Length=378, Percent_Identity=23.5449735449735, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=40.9090909090909, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=33.5012594458438, Blast_Score=231, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI25147133, Length=394, Percent_Identity=33.756345177665, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71981858, Length=392, Percent_Identity=33.1632653061224, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17569539, Length=399, Percent_Identity=31.328320802005, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17569537, Length=391, Percent_Identity=25.8312020460358, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=32.8638497652582, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17550384, Length=230, Percent_Identity=27.3913043478261, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323055, Length=401, Percent_Identity=33.1670822942643, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6322743, Length=428, Percent_Identity=26.1682242990654, Blast_Score=167, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24580972, Length=391, Percent_Identity=32.9923273657289, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24580970, Length=391, Percent_Identity=32.9923273657289, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI19920542, Length=384, Percent_Identity=33.0729166666667, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=34.0852130325814, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=34.0852130325814, Blast_Score=213, Evalue=1e-55,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42709; Mature: 42578

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFSPLSTLPPDALLGLMTAYRADERSEKFDLGVGVYKDENGETPILSAVRKAEAKMLA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHHH
AQTTKVYEGPRGNTDFCAHIEKFVFGKDHPALAENRVLSFTSPGGCGALFLGVGLMRRMG
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCHHHHHHHHHHHHHCC
TRRVWVSRPTWPNHPNVVKSLGLDVKEYTYSRDGAFYRLGALADLSTAERGDGIIIQGPC
CCEEEEECCCCCCCCHHHHHHCCCHHHHEECCCCCEEEECCHHCCCCCCCCCEEEEECCC
HNPTGIDPSTEDWRELGKLCKDKGIIALLDVAYHGFASGLDRDMDGVRAFIDEAGEALIS
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEE
YSCSKNFGLYRERTGCFLAVGAEAEGIAAATTHVADMGRATWSMPPSHGAGIVATILDDP
ECCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCC
DLRAEWETELSAMRTRMIGLREALSDALVSHSGSNLLAALKTQNGMFSQLPISAEDTAKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCCCCHHHHH
READGIYMPSSGRINIAGLHPSDIPRLAEILAGYLV
HCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SHFSPLSTLPPDALLGLMTAYRADERSEKFDLGVGVYKDENGETPILSAVRKAEAKMLA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHHH
AQTTKVYEGPRGNTDFCAHIEKFVFGKDHPALAENRVLSFTSPGGCGALFLGVGLMRRMG
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCHHHHHHHHHHHHHCC
TRRVWVSRPTWPNHPNVVKSLGLDVKEYTYSRDGAFYRLGALADLSTAERGDGIIIQGPC
CCEEEEECCCCCCCCHHHHHHCCCHHHHEECCCCCEEEECCHHCCCCCCCCCEEEEECCC
HNPTGIDPSTEDWRELGKLCKDKGIIALLDVAYHGFASGLDRDMDGVRAFIDEAGEALIS
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEE
YSCSKNFGLYRERTGCFLAVGAEAEGIAAATTHVADMGRATWSMPPSHGAGIVATILDDP
ECCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCC
DLRAEWETELSAMRTRMIGLREALSDALVSHSGSNLLAALKTQNGMFSQLPISAEDTAKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCCCCHHHHH
READGIYMPSSGRINIAGLHPSDIPRLAEILAGYLV
HCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]