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The map label for this gene is infC

Identifier: 114799954

GI number: 114799954

Start: 426869

End: 427411

Strand: Direct

Name: infC

Synonym: HNE_0428

Alternate gene names: 114799954

Gene position: 426869-427411 (Clockwise)

Preceding gene: 114798117

Following gene: 114797173

Centisome position: 11.52

GC content: 58.2

Gene sequence:

>543_bases
ATAGCTCGCAGACCTGAAGCCGATGCGCCGCCCAAGAAACAGGCTGGCCCCCGCATCAATGAAGAAATCCGCGCCGCCAA
GGTGCTGCTGATTGACGAGAATGGCGAGAAGCAGGGTGTGATGCCCCTGGCCGCCGCGCTTGACGCGGCTCGAGAAGCAT
CGATGGACCTTGTTGAGGTCTCTGCCGGTCAGGAAACCCCGGTCGTCAAGATTCTCGATTACGGCAAGTTGCGCTTTGAA
GAGCGCAAGAAGAAGGCTGCTGCCCGTAAGAAGCAGAAGTCTTCGGAGCTGAAAGAGATCAAGATCCGCCCCAATATCGA
CACCCACGACTATGAAGTGAAGGCGCGGGCGATCGCGCGTTTCTTTGAAGAGGGCGACAAGGTGAAGATCACCCTGCGCT
TCCGTGGCCGTGAGATGGCGCACCAGCATCTGGGCATGGAACTGCTCGAGAAGGTGAAAAAGGATTTCGAGGAGACCGCA
AAGGTCGAACTCGAACCCAAGCTCGAAGGCAAGCAGATGACCATGGTGCTCGCCCCGCGCTGA

Upstream 100 bases:

>100_bases
TTGACCTGACGCTGCGCCCCGATTAGGGCGCCACGCTTGCCGCAAGCGGCGAATACAGGCATATTCCCGCAACTTTCTGA
GCAACCAAAGGAGATCTCCC

Downstream 100 bases:

>100_bases
GGCGGAGTGTTCCCTCGATACAGAAAAAGCCCTCGCGCTGCGGGGGCTTTTTCATTTGGCCAGACCAATCGCAGCGCTCC
GCCGATGGATCGTTTGAGGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEVSAGQETPVVKILDYGKLRFE
ERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIARFFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETA
KVELEPKLEGKQMTMVLAPR

Sequences:

>Translated_180_residues
MARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEVSAGQETPVVKILDYGKLRFE
ERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIARFFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETA
KVELEPKLEGKQMTMVLAPR
>Mature_179_residues
ARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEVSAGQETPVVKILDYGKLRFEE
RKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIARFFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETAK
VELEPKLEGKQMTMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=56.0975609756098, Blast_Score=165, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_HYPNA (Q0C535)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759158.1
- ProteinModelPortal:   Q0C535
- STRING:   Q0C535
- GeneID:   4290109
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0428
- NMPDR:   fig|228405.5.peg.421
- TIGR:   HNE_0428
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- PhylomeDB:   Q0C535
- ProtClustDB:   PRK00028
- BioCyc:   HNEP81032:HNE_0428-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20429; Mature: 20298

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEV
CCCCCCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAGQETPVVKILDYGKLRFEERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIAR
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHH
FFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETAKVELEPKLEGKQMTMVLAPR
HHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure 
ARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEV
CCCCCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAGQETPVVKILDYGKLRFEERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIAR
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHH
FFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETAKVELEPKLEGKQMTMVLAPR
HHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA