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The map label for this gene is cirA [H]

Identifier: 114799872

GI number: 114799872

Start: 209986

End: 212790

Strand: Direct

Name: cirA [H]

Synonym: HNE_0220

Alternate gene names: 114799872

Gene position: 209986-212790 (Clockwise)

Preceding gene: 114800332

Following gene: 114797105

Centisome position: 5.67

GC content: 60.75

Gene sequence:

>2805_bases
ATGACCGCGCTTCAGTTCGCGACGGGGTCTGCCCAGGTTATCGCCAGCTCGCCGGCGACCTTTGAAATCGAGTCCCAGTC
CCTCGCCAAGGCGCTGGTGAAGTATTCAGAACAGTCTCACCTTGTCATCGTGGCGCCTGAGGAGCTTGTCGAAGGCAAGA
CTTCTGCGCGGGTGCAGGGCGTTCTGGCGCCGGAGCAGGCGCTCAACAGCCTTCTGTCCGGGACCGGGCTGACAGCGCAA
TCGCATAAGAATGGCGCGCTGACGCTGAAACGGACATGGGTTGAGGAGGGCCGGGGACCAGCGGGCCCTTTAGTGCTGGC
TCAGGCGACAACAGCCGCGCCCCAGCCAGCTCCAGCCCCCGCGACTAGCCCGGCAGAAGAAGAGTCTCCCAGCATTCAGG
AAACGGTTATCGTGACCGGTGTGCGCGGCGCGCCGCGCTCGGTGATCGACAGCCCGACGCCTATCGATGTGTTCTCGGCT
GAAGACATCCAGCAGGGGAGCCCGACCGGGGTGTTTGAGTCCCTGCGGTATCTCGTTCCCTCCTTCAACCTGCCCACCCG
TGCAGGCGGCGGCACAGCCACCGTGATCGCTACGGGCGGCTTACGCGGCCTGAACCCGGACCACACGCTGGTGCTCGTCA
ACGGCAAGCGCCGGCACAAGACCGCGCTCATCAACTCGGTCTCCTCGCTCTATAATGGTGCGGCGGGTGTCGACCTGAAC
ATGATCCCGTCCTCGGCGATTGCGCGGATTGAAGTGCTGCGCGATGGCGCCGCGGCGCAGTATGGCTCTGACGCCATTGC
CGGCGTGATCAACATCATTCTCAAAGATGCGCCCGAAGGCGGCGAGGCATCTGTCAGCTTCGGCGAGAATATGGACCGCT
CCGACGGCGAATTCCTTACCGGCTCGGTCAACCAGGGCTACGCGATCGGGGACAGCGGGTTTGCGCATTTGTCCTACAGC
TATATGGACCGGAATGCGTCCAACCGCGCAGTGCCGATTGCCGACTCTGTGAACCTCTATCCGCTGCTTCCCGACGGTTC
GCGCGATCCGCGGGAGGCGAGCATAGACCGCCTTGTCACCACGAATTACGGGGCCTTCCCGCAGACGTCGCACACATTCG
GGGCCACTCTCGGTTATGAAACCAAGGGCGTCGAACTCTACGCCTTCGGCACCTATGGCGCGCGCACGTCCGTGCTCGAC
TGGTCGTTCCGTGCCCCTAATAACCTTGCATCGCTGCCGGAAGTTTATCCCAACGGTTTCAGTCCGCGCCTGACCATCTA
TGAAGATGACCTTGAGGTTGCAGGGGGTATCCGCGGCAGCTTTGACGAATGGGGATGGGACCTCTCCAGCAACTTCGGCA
CCGACATCACCGATTGGGAAAACGACAATGGCCTGAATGCCAGCCTCGGGCCGGCGAGCCCGACGCATTTTGAAGTGGGC
CGCCTGATTTCGTCCGAATGGGTCAACTCGTTTGATGCGACGCGGGCCTATGATCTGACCGATGCCGGTGAGCTGCAGGT
GTCGTTTGGTTTCCAGCATCGCCTGGAGAAATACGAGATCGAGCAGGGCGACGAAGCCAGCTGGGCGGCGGGCAGCTATG
TGCGTCCTCCCGGTCAGCCGTTTGAGGGGCAGGTGCAGACGCCGGGTTCCCAGGCAACGCCCGGCTTCCGTCCGGATGAC
GCAGGCTCTGTGGAGCGCAACAACCTGTCAGCCTATGGCGAGCTGGGCTGGAGCGCGACCGACAAGCTGTTCATTTCCGG
CGCCGCGCGATTTGAAAGCTTTGATGATGATGCGGGCGAGGAGCTGATCTACAAGGTCAACGGGCGTTACGAGTTCACCG
ACTGGGTAGCGGCGCGGGCATCCTACAATACAGGCTTCCGTGCGCCGACACCGGCCCAGCAGGCCTATTCCTCCACCACC
AGTCAGTTCCGCGATCTGGATGGCGATGGTGAGAATGAGCTGCTGCTCCTGAAAAACCTGCCGGTCGACTCGGCCGCAGC
TATCGCTCTTGGGTCATCGCCGCTGGTTCCGGAAACATCCACGAATGCCAGCATCGGCCTCACCCTGACGCCGTTGAGCA
ACCTGGCTGTCACCATTGATGCCTACCGGATCGATGTGGATGACCGGATCGCAGTGACAACCACCTTCTCGCCGCTCGAC
AACCGTCTGTCGGCGGACGGCGTCACCACGATCGGTGACCAGATCCAGTCGATTCTGACAGCTAACGGGCTGCCCGCCGA
GATCAGCGGCCAGTATTACACCAATGCCATCGATACACGCACGGAAGGTATCGATGTTGTGGCCACCTACACGATTCCGA
CTGACTCCCTCGGCGATTTCGCGGTCAAGGCCGGGTATAACAAGAACACAACCGAGATCACGGGCATCATCGATAATCCG
GCGGCGCTTTCGGCCCTTGGGGATATCGAGATTTTTGACCGCAGCAAGCAGGGCGCGCTGACTGACTCCATACCGGACTC
CAAGATCACGCTTGGTCTTGATTGGGTGTTTGGAAAGTTCTCTGCAAACGCCCGGACGACCCGATTTGGCACGTATACCG
TTCTGAATGCGACCAATCCGTCCGCCGACTATGATGTCGATCCCGCCTGGATCACGGACATTGAGATTGGATATGAAATC
AGTGAGGCGCTCAGTGTCTTCGCTGGCGCGAACAACGTGTTCAACGAGTACCCGCAGGAAATCAATCCTCCGGGCGCCAC
CAACGGCTCGAACATGTACAACACGTTTGCGCCATTTGGTTTCACGGGCGGATCATGGTTCGTGCGCGGTATATATAAGT
GGTGA

Upstream 100 bases:

>100_bases
GAAGTCTGGCCGTTTCAACCAGGCAGTCACTTCGGGGTTACAAGTCATGCGCAAGACGCTTCATCCAATTCTCCGGGCAA
GTCTCGCGGGGGCGGTCTCA

Downstream 100 bases:

>100_bases
TCTGACAGGGCTGGCCCGGTGGCGAGGTGCTTCCGGGCCAATCTTTTTACGACAGTCATGACAAGAATAAATGAGAGGAT
TTAAGGGATGAGACATATCA

Product: outer membrane receptor (OMR) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 934; Mature: 933

Protein sequence:

>934_residues
MTALQFATGSAQVIASSPATFEIESQSLAKALVKYSEQSHLVIVAPEELVEGKTSARVQGVLAPEQALNSLLSGTGLTAQ
SHKNGALTLKRTWVEEGRGPAGPLVLAQATTAAPQPAPAPATSPAEEESPSIQETVIVTGVRGAPRSVIDSPTPIDVFSA
EDIQQGSPTGVFESLRYLVPSFNLPTRAGGGTATVIATGGLRGLNPDHTLVLVNGKRRHKTALINSVSSLYNGAAGVDLN
MIPSSAIARIEVLRDGAAAQYGSDAIAGVINIILKDAPEGGEASVSFGENMDRSDGEFLTGSVNQGYAIGDSGFAHLSYS
YMDRNASNRAVPIADSVNLYPLLPDGSRDPREASIDRLVTTNYGAFPQTSHTFGATLGYETKGVELYAFGTYGARTSVLD
WSFRAPNNLASLPEVYPNGFSPRLTIYEDDLEVAGGIRGSFDEWGWDLSSNFGTDITDWENDNGLNASLGPASPTHFEVG
RLISSEWVNSFDATRAYDLTDAGELQVSFGFQHRLEKYEIEQGDEASWAAGSYVRPPGQPFEGQVQTPGSQATPGFRPDD
AGSVERNNLSAYGELGWSATDKLFISGAARFESFDDDAGEELIYKVNGRYEFTDWVAARASYNTGFRAPTPAQQAYSSTT
SQFRDLDGDGENELLLLKNLPVDSAAAIALGSSPLVPETSTNASIGLTLTPLSNLAVTIDAYRIDVDDRIAVTTTFSPLD
NRLSADGVTTIGDQIQSILTANGLPAEISGQYYTNAIDTRTEGIDVVATYTIPTDSLGDFAVKAGYNKNTTEITGIIDNP
AALSALGDIEIFDRSKQGALTDSIPDSKITLGLDWVFGKFSANARTTRFGTYTVLNATNPSADYDVDPAWITDIEIGYEI
SEALSVFAGANNVFNEYPQEINPPGATNGSNMYNTFAPFGFTGGSWFVRGIYKW

Sequences:

>Translated_934_residues
MTALQFATGSAQVIASSPATFEIESQSLAKALVKYSEQSHLVIVAPEELVEGKTSARVQGVLAPEQALNSLLSGTGLTAQ
SHKNGALTLKRTWVEEGRGPAGPLVLAQATTAAPQPAPAPATSPAEEESPSIQETVIVTGVRGAPRSVIDSPTPIDVFSA
EDIQQGSPTGVFESLRYLVPSFNLPTRAGGGTATVIATGGLRGLNPDHTLVLVNGKRRHKTALINSVSSLYNGAAGVDLN
MIPSSAIARIEVLRDGAAAQYGSDAIAGVINIILKDAPEGGEASVSFGENMDRSDGEFLTGSVNQGYAIGDSGFAHLSYS
YMDRNASNRAVPIADSVNLYPLLPDGSRDPREASIDRLVTTNYGAFPQTSHTFGATLGYETKGVELYAFGTYGARTSVLD
WSFRAPNNLASLPEVYPNGFSPRLTIYEDDLEVAGGIRGSFDEWGWDLSSNFGTDITDWENDNGLNASLGPASPTHFEVG
RLISSEWVNSFDATRAYDLTDAGELQVSFGFQHRLEKYEIEQGDEASWAAGSYVRPPGQPFEGQVQTPGSQATPGFRPDD
AGSVERNNLSAYGELGWSATDKLFISGAARFESFDDDAGEELIYKVNGRYEFTDWVAARASYNTGFRAPTPAQQAYSSTT
SQFRDLDGDGENELLLLKNLPVDSAAAIALGSSPLVPETSTNASIGLTLTPLSNLAVTIDAYRIDVDDRIAVTTTFSPLD
NRLSADGVTTIGDQIQSILTANGLPAEISGQYYTNAIDTRTEGIDVVATYTIPTDSLGDFAVKAGYNKNTTEITGIIDNP
AALSALGDIEIFDRSKQGALTDSIPDSKITLGLDWVFGKFSANARTTRFGTYTVLNATNPSADYDVDPAWITDIEIGYEI
SEALSVFAGANNVFNEYPQEINPPGATNGSNMYNTFAPFGFTGGSWFVRGIYKW
>Mature_933_residues
TALQFATGSAQVIASSPATFEIESQSLAKALVKYSEQSHLVIVAPEELVEGKTSARVQGVLAPEQALNSLLSGTGLTAQS
HKNGALTLKRTWVEEGRGPAGPLVLAQATTAAPQPAPAPATSPAEEESPSIQETVIVTGVRGAPRSVIDSPTPIDVFSAE
DIQQGSPTGVFESLRYLVPSFNLPTRAGGGTATVIATGGLRGLNPDHTLVLVNGKRRHKTALINSVSSLYNGAAGVDLNM
IPSSAIARIEVLRDGAAAQYGSDAIAGVINIILKDAPEGGEASVSFGENMDRSDGEFLTGSVNQGYAIGDSGFAHLSYSY
MDRNASNRAVPIADSVNLYPLLPDGSRDPREASIDRLVTTNYGAFPQTSHTFGATLGYETKGVELYAFGTYGARTSVLDW
SFRAPNNLASLPEVYPNGFSPRLTIYEDDLEVAGGIRGSFDEWGWDLSSNFGTDITDWENDNGLNASLGPASPTHFEVGR
LISSEWVNSFDATRAYDLTDAGELQVSFGFQHRLEKYEIEQGDEASWAAGSYVRPPGQPFEGQVQTPGSQATPGFRPDDA
GSVERNNLSAYGELGWSATDKLFISGAARFESFDDDAGEELIYKVNGRYEFTDWVAARASYNTGFRAPTPAQQAYSSTTS
QFRDLDGDGENELLLLKNLPVDSAAAIALGSSPLVPETSTNASIGLTLTPLSNLAVTIDAYRIDVDDRIAVTTTFSPLDN
RLSADGVTTIGDQIQSILTANGLPAEISGQYYTNAIDTRTEGIDVVATYTIPTDSLGDFAVKAGYNKNTTEITGIIDNPA
ALSALGDIEIFDRSKQGALTDSIPDSKITLGLDWVFGKFSANARTTRFGTYTVLNATNPSADYDVDPAWITDIEIGYEIS
EALSVFAGANNVFNEYPQEINPPGATNGSNMYNTFAPFGFTGGSWFVRGIYKW

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=174, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1790405, Length=167, Percent_Identity=34.1317365269461, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790743, Length=291, Percent_Identity=25.7731958762887, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 99420; Mature: 99289

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALQFATGSAQVIASSPATFEIESQSLAKALVKYSEQSHLVIVAPEELVEGKTSARVQG
CCEEEECCCCCEEEECCCCEEEECHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCEEEE
VLAPEQALNSLLSGTGLTAQSHKNGALTLKRTWVEEGRGPAGPLVLAQATTAAPQPAPAP
EECHHHHHHHHHCCCCCEECCCCCCCEEEEEEHHHCCCCCCCCEEEEEECCCCCCCCCCC
ATSPAEEESPSIQETVIVTGVRGAPRSVIDSPTPIDVFSAEDIQQGSPTGVFESLRYLVP
CCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCEEEECCCHHCCCCCCHHHHHHHHHCC
SFNLPTRAGGGTATVIATGGLRGLNPDHTLVLVNGKRRHKTALINSVSSLYNGAAGVDLN
CCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
MIPSSAIARIEVLRDGAAAQYGSDAIAGVINIILKDAPEGGEASVSFGENMDRSDGEFLT
ECCCHHHHEEHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEE
GSVNQGYAIGDSGFAHLSYSYMDRNASNRAVPIADSVNLYPLLPDGSRDPREASIDRLVT
CCCCCCEEECCCCCEEEEEEHHCCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHEEE
TNYGAFPQTSHTFGATLGYETKGVELYAFGTYGARTSVLDWSFRAPNNLASLPEVYPNGF
CCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHCCCCC
SPRLTIYEDDLEVAGGIRGSFDEWGWDLSSNFGTDITDWENDNGLNASLGPASPTHFEVG
CCEEEEEECCHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLISSEWVNSFDATRAYDLTDAGELQVSFGFQHRLEKYEIEQGDEASWAAGSYVRPPGQP
HHHHHHHHCCCCCCEEECCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FEGQVQTPGSQATPGFRPDDAGSVERNNLSAYGELGWSATDKLFISGAARFESFDDDAGE
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCHHCCCCCCCCCC
ELIYKVNGRYEFTDWVAARASYNTGFRAPTPAQQAYSSTTSQFRDLDGDGENELLLLKNL
EEEEEECCEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECC
PVDSAAAIALGSSPLVPETSTNASIGLTLTPLSNLAVTIDAYRIDVDDRIAVTTTFSPLD
CCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEEEECCCCC
NRLSADGVTTIGDQIQSILTANGLPAEISGQYYTNAIDTRTEGIDVVATYTIPTDSLGDF
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCE
AVKAGYNKNTTEITGIIDNPAALSALGDIEIFDRSKQGALTDSIPDSKITLGLDWVFGKF
EEECCCCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEE
SANARTTRFGTYTVLNATNPSADYDVDPAWITDIEIGYEISEALSVFAGANNVFNEYPQE
CCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHCHHH
INPPGATNGSNMYNTFAPFGFTGGSWFVRGIYKW
CCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TALQFATGSAQVIASSPATFEIESQSLAKALVKYSEQSHLVIVAPEELVEGKTSARVQG
CEEEECCCCCEEEECCCCEEEECHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCEEEE
VLAPEQALNSLLSGTGLTAQSHKNGALTLKRTWVEEGRGPAGPLVLAQATTAAPQPAPAP
EECHHHHHHHHHCCCCCEECCCCCCCEEEEEEHHHCCCCCCCCEEEEEECCCCCCCCCCC
ATSPAEEESPSIQETVIVTGVRGAPRSVIDSPTPIDVFSAEDIQQGSPTGVFESLRYLVP
CCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCEEEECCCHHCCCCCCHHHHHHHHHCC
SFNLPTRAGGGTATVIATGGLRGLNPDHTLVLVNGKRRHKTALINSVSSLYNGAAGVDLN
CCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
MIPSSAIARIEVLRDGAAAQYGSDAIAGVINIILKDAPEGGEASVSFGENMDRSDGEFLT
ECCCHHHHEEHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEE
GSVNQGYAIGDSGFAHLSYSYMDRNASNRAVPIADSVNLYPLLPDGSRDPREASIDRLVT
CCCCCCEEECCCCCEEEEEEHHCCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHEEE
TNYGAFPQTSHTFGATLGYETKGVELYAFGTYGARTSVLDWSFRAPNNLASLPEVYPNGF
CCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHCCCCC
SPRLTIYEDDLEVAGGIRGSFDEWGWDLSSNFGTDITDWENDNGLNASLGPASPTHFEVG
CCEEEEEECCHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLISSEWVNSFDATRAYDLTDAGELQVSFGFQHRLEKYEIEQGDEASWAAGSYVRPPGQP
HHHHHHHHCCCCCCEEECCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FEGQVQTPGSQATPGFRPDDAGSVERNNLSAYGELGWSATDKLFISGAARFESFDDDAGE
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCHHCCCCCCCCCC
ELIYKVNGRYEFTDWVAARASYNTGFRAPTPAQQAYSSTTSQFRDLDGDGENELLLLKNL
EEEEEECCEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECC
PVDSAAAIALGSSPLVPETSTNASIGLTLTPLSNLAVTIDAYRIDVDDRIAVTTTFSPLD
CCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEEEECCCCC
NRLSADGVTTIGDQIQSILTANGLPAEISGQYYTNAIDTRTEGIDVVATYTIPTDSLGDF
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCE
AVKAGYNKNTTEITGIIDNPAALSALGDIEIFDRSKQGALTDSIPDSKITLGLDWVFGKF
EEECCCCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEE
SANARTTRFGTYTVLNATNPSADYDVDPAWITDIEIGYEISEALSVFAGANNVFNEYPQE
CCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHCHHH
INPPGATNGSNMYNTFAPFGFTGGSWFVRGIYKW
CCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]