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The map label for this gene is pyrF [H]

Identifier: 114799810

GI number: 114799810

Start: 112944

End: 113813

Strand: Direct

Name: pyrF [H]

Synonym: HNE_0128

Alternate gene names: 114799810

Gene position: 112944-113813 (Clockwise)

Preceding gene: 114799432

Following gene: 114797244

Centisome position: 3.05

GC content: 66.67

Gene sequence:

>870_bases
ATGACCGATTTTGCCACCCGACTCACCGAAGGTACGCGCAAGTTTGGGCCCCTCTGTGTGGGGATTGACCCACATGCGGG
CATGATTCCGGACCTGTTTGGCGGAGATACGCCCGAAGGTATCTGGAAATGGTCGCAGGCGATTATCGAGGCCGCGGCCG
GCAAGGTTGCGGTCGTCAAGCCGCAGGCGAGCCTGTTCGAGCGTCACGGGCCAGAAGGCATGGCGGCGCTGCAGGCCGCC
GCCAAGGCAGCGCGGGCGGCGGGGCTGATCGTTCTGATGGATGCAAAGCGTGGCGACATCGGCACAACGGCGGAAGGCTA
TGCGCAGGCGTATCTGGCGCCGGGCGCGCCGTTTGAGGGCGATGCCCTGACAGTGAACCCTTATATGGGCCTCGACACGC
TGGAGCCTTACGCAAAGCAGGCCAAGGCGCATGGCAAGGGCGTGATCGTACTTGTGCGCACGTCCAACCCCGGCGCGGCA
GATTTCCAGTCGCGCATCATGGGCGGCGCGCCGCTCTATGTGCGGGTGGCCGAAGCCCTGACCCCGCTGACCGAGCGTCT
GATGAGCCCGTGCGGCTGGTCTAACCTGATGATGGTGATTGGCGCGACGGCCCCTGAGGAAGCGCGCGCGGTGCGGGCGC
TGGCACCCAAGGCGTTGTTTCTGGTGCCTGGCTATGGCGCGCAGGGCGCGGCGGCCGAAGAGGCCTGTTCGGGCCTCGTG
AACGGGGAAGGCGGCGTCGTCAGCGCCTCGCGTTCGGTCAATTTTCCCAAGGCTGCCGCGAACGCCGGAGACAAGGCCAG
CTGGCGCCGTGCCATCGAAGACGCCATCCTTCAGGCGCGCGATGAGCTGCGCCTGGCGGCGGTTGCCTGA

Upstream 100 bases:

>100_bases
CGGGTCCTTCCGACGTGTTCCGCGTGCGCGACTATGGTGCGGCTTCGGACACGGCCCGGCGCCGCTTGCAGGTCGTCAAG
GTTATGTGCGAGGTGGGCTC

Downstream 100 bases:

>100_bases
GCGGGCCGACTCCCGCCGCGTCATGGCTCGACATTACCCTACAAGCAGCTAGTCTCCCGGCCATATGATCCTGCGCGCGC
CTGCGCGGCAGGGCGAGGTC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTDFATRLTEGTRKFGPLCVGIDPHAGMIPDLFGGDTPEGIWKWSQAIIEAAAGKVAVVKPQASLFERHGPEGMAALQAA
AKAARAAGLIVLMDAKRGDIGTTAEGYAQAYLAPGAPFEGDALTVNPYMGLDTLEPYAKQAKAHGKGVIVLVRTSNPGAA
DFQSRIMGGAPLYVRVAEALTPLTERLMSPCGWSNLMMVIGATAPEEARAVRALAPKALFLVPGYGAQGAAAEEACSGLV
NGEGGVVSASRSVNFPKAAANAGDKASWRRAIEDAILQARDELRLAAVA

Sequences:

>Translated_289_residues
MTDFATRLTEGTRKFGPLCVGIDPHAGMIPDLFGGDTPEGIWKWSQAIIEAAAGKVAVVKPQASLFERHGPEGMAALQAA
AKAARAAGLIVLMDAKRGDIGTTAEGYAQAYLAPGAPFEGDALTVNPYMGLDTLEPYAKQAKAHGKGVIVLVRTSNPGAA
DFQSRIMGGAPLYVRVAEALTPLTERLMSPCGWSNLMMVIGATAPEEARAVRALAPKALFLVPGYGAQGAAAEEACSGLV
NGEGGVVSASRSVNFPKAAANAGDKASWRRAIEDAILQARDELRLAAVA
>Mature_288_residues
TDFATRLTEGTRKFGPLCVGIDPHAGMIPDLFGGDTPEGIWKWSQAIIEAAAGKVAVVKPQASLFERHGPEGMAALQAAA
KAARAAGLIVLMDAKRGDIGTTAEGYAQAYLAPGAPFEGDALTVNPYMGLDTLEPYAKQAKAHGKGVIVLVRTSNPGAAD
FQSRIMGGAPLYVRVAEALTPLTERLMSPCGWSNLMMVIGATAPEEARAVRALAPKALFLVPGYGAQGAAAEEACSGLVN
GEGGVVSASRSVNFPKAAANAGDKASWRRAIEDAILQARDELRLAAVA

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 29928; Mature: 29796

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFATRLTEGTRKFGPLCVGIDPHAGMIPDLFGGDTPEGIWKWSQAIIEAAAGKVAVVK
CCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEC
PQASLFERHGPEGMAALQAAAKAARAAGLIVLMDAKRGDIGTTAEGYAQAYLAPGAPFEG
CHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCCC
DALTVNPYMGLDTLEPYAKQAKAHGKGVIVLVRTSNPGAADFQSRIMGGAPLYVRVAEAL
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHH
TPLTERLMSPCGWSNLMMVIGATAPEEARAVRALAPKALFLVPGYGAQGAAAEEACSGLV
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCCC
NGEGGVVSASRSVNFPKAAANAGDKASWRRAIEDAILQARDELRLAAVA
CCCCCEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
TDFATRLTEGTRKFGPLCVGIDPHAGMIPDLFGGDTPEGIWKWSQAIIEAAAGKVAVVK
CCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEC
PQASLFERHGPEGMAALQAAAKAARAAGLIVLMDAKRGDIGTTAEGYAQAYLAPGAPFEG
CHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCCC
DALTVNPYMGLDTLEPYAKQAKAHGKGVIVLVRTSNPGAADFQSRIMGGAPLYVRVAEAL
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHH
TPLTERLMSPCGWSNLMMVIGATAPEEARAVRALAPKALFLVPGYGAQGAAAEEACSGLV
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCCC
NGEGGVVSASRSVNFPKAAANAGDKASWRRAIEDAILQARDELRLAAVA
CCCCCEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA