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The map label for this gene is adhA [H]

Identifier: 114797244

GI number: 114797244

Start: 113966

End: 116119

Strand: Direct

Name: adhA [H]

Synonym: HNE_0129

Alternate gene names: 114797244

Gene position: 113966-116119 (Clockwise)

Preceding gene: 114799810

Following gene: 114798229

Centisome position: 3.08

GC content: 63.93

Gene sequence:

>2154_bases
ATGGCAGGCGCTCTGGCGGCGCTGGTGCTGGCTGCCTGCGGGCAGGGGCAGGTCCAGAAGGCCGAGCCGCGCGGCTTTGC
CGCCGTGGATACGGCGCGGATTTCGGCCGAGAGCGCCGGAAATGAGTGGCTGACCTATGGCGGCACCTATGACGAGCAGC
GCCATTCCAAGCTGACCGCGATCAACAAGGAAAATGTCGGCGAGCTGGGCGTTGCCTGGACCTATGACCTGGCCACCAAT
CGCGGCGTCGAATCGACGCCCATCGTGGTCGACGGGGTGATGTATGTCACGTCCGCCTGGTCGGTCGTTTATGCGCTGGA
CGCAAAGACCGGCGAAGAGAAATGGGTTTACGATCCGGGCGCGGATCGCGCCGTGGGCGTGAAGGCGTGCTGTGATGTCG
TGAACCGGGGCGTCGCTGTCTATGACGGCAAGGTCTATGTCGGCGTAATTGACGGGCGGCTTGAAGCGCTCAACGCCGAG
ACCGGCGAAGTCATCTGGAGCAAGGTGACAGTCGATCAGGAGAAGCCCTACACGATCACCGGCGCGCCGCGTGTGGTGAA
CGGCAAGGTGCTGATCGGCAATGGCGGGGCAGAGCTGGGCGTGCGCGGCTATCTCTCCGCTTACGATACAAGCTCAGGCG
ATCTGGTCTGGCGTTTCTACACAGTACCCAATCCGAAAAAGCAGCCAGACGGCGCAGCGTCTGATGACGCCTTCGTGCAG
GTCGGCAATGTGACCTGGGGCGATGAAGGCGCGTGGACCACCGATGGCGGTGGCGGCACTGTCTGGGATTCGATCGTCTA
TGACGAGGTGAACAACCAGATCATCTTCGGCGTCGGCAATGGGTCGCCCTGGAACCGGACGTTCCGCGATCCTTCGGCCG
GGGACAATCTGTTCCTCTCCTCCATCGTGGCGGTGGATCTGGAGACGGGCGCGTACAAGTGGCACTTCCAGACTACGCCG
GGCGATAACTGGGATTACACGGCCACGCAGACGATCATTCTGGCGGACCTGCCGCTGGGCGAGAATGGCGCCTCGCGCCG
GGTCGCCATGCAGGCACCCAAGAACGGCTTCTTCTATGTGATCGATGCGGCGACCGGTGAGTATATCTCGGGCGACGCCT
ATGTGCCGACCAACTGGGCGACCGGCCTGGATGAAAACGGCCGGCCGATCGAAGTGCCCGAGGCCCGCTATACCAAGCAG
CCCTTCGAGCAGACACCTGGCCCGCTCGGCGGCCATAACTGGCATCCGATGGCCTTCAATCCCGATGAGGGCCTGGCTTA
TATTCCAGCCCAGGAGATTCCGCAGGCTTATGCCGAGGATTCCCGCTTCACCGCGCGGCCCGTCAGCTGGAATACCGGCA
TTGATTTCTCGGCGGGCGTGCCCCCGATTGCCCCGCCGGATGTGGCGAAATTCCTGCGGGCGAGCCTCAAGGGCCGCCTG
ATTGCCTGGGACCCGATTGCCCGCGCCCCGCGCTGGAGCGTCGAGCATGAGAATGCCTGGAATGGCGGCGTGCTGTCGAC
GGCAGGCGGAGTTGTCTTCCAGGGCAAGCTGGGCGGCGAGTTTGTCGCGTATGATGCGGCCACCGGCGACAAGCTGTGGA
GCCATGAGCTGAAATCGGGCGGCGCGTCCGGCCCCGGCACGTTCATGATCGATGGCGAGCAGTATGTGACGATCACCACC
GGCTGGGGCTCTGCCTTCGCGCTGGCGGCAGGATTTGCCTATGATGAGAAAGTGGAATCCACCGTCGGCAAGGTCGTGAC
GTTCAAGCTCGGCGCGACGGGTGAGATTGCAGATTCCGGCCTGCCGCCGATTGATGCAACGCCCAAGGCCGAAGCGTTCG
GGTCGATGGCCGTCATCTCTGAAGGTGCGGTCCACTATGCGCGTAACTGCGCGGTGTGCCATGGTCCGCTCGGGGTTTCC
TCCGGCGTGCTGCCGGATCTGCGCTGGTCTGCGATCTCGGCCAATGCCGATGCCTGGAAGGGCGTCGTGCTGGACGGCAA
CCTTGCCGCAAACGGCATGGTCTCGTTTGCCGATTACATCACGCCGGACGAGTCTGAAGCGATCCGCGCCTATGTGCTGA
CGCAGGCGCATGCGGCGGTCACACCTGCCGAAGCGGCGCCGGCGGAAGAGAGCCCGCCCGCCGAAGACAACTGA

Upstream 100 bases:

>100_bases
TCTCCCGGCCATATGATCCTGCGCGCGCCTGCGCGGCAGGGCGAGGTCTGGGAGGATTATCGTGAGCAAATTTGTGACGG
CCCGTTGGGCCAGCCCCGTG

Downstream 100 bases:

>100_bases
TCTTCCGCATCGGTGAGATACTGCAAAAGACAGAACGGGGCCTCACATCGAGGCCCCGTTTTTTTGCGTTCGTGCGGGCA
GGGCAACCTTACAGAATTGG

Product: alcohol dehydrogenase (acceptor)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MAGALAALVLAACGQGQVQKAEPRGFAAVDTARISAESAGNEWLTYGGTYDEQRHSKLTAINKENVGELGVAWTYDLATN
RGVESTPIVVDGVMYVTSAWSVVYALDAKTGEEKWVYDPGADRAVGVKACCDVVNRGVAVYDGKVYVGVIDGRLEALNAE
TGEVIWSKVTVDQEKPYTITGAPRVVNGKVLIGNGGAELGVRGYLSAYDTSSGDLVWRFYTVPNPKKQPDGAASDDAFVQ
VGNVTWGDEGAWTTDGGGGTVWDSIVYDEVNNQIIFGVGNGSPWNRTFRDPSAGDNLFLSSIVAVDLETGAYKWHFQTTP
GDNWDYTATQTIILADLPLGENGASRRVAMQAPKNGFFYVIDAATGEYISGDAYVPTNWATGLDENGRPIEVPEARYTKQ
PFEQTPGPLGGHNWHPMAFNPDEGLAYIPAQEIPQAYAEDSRFTARPVSWNTGIDFSAGVPPIAPPDVAKFLRASLKGRL
IAWDPIARAPRWSVEHENAWNGGVLSTAGGVVFQGKLGGEFVAYDAATGDKLWSHELKSGGASGPGTFMIDGEQYVTITT
GWGSAFALAAGFAYDEKVESTVGKVVTFKLGATGEIADSGLPPIDATPKAEAFGSMAVISEGAVHYARNCAVCHGPLGVS
SGVLPDLRWSAISANADAWKGVVLDGNLAANGMVSFADYITPDESEAIRAYVLTQAHAAVTPAEAAPAEESPPAEDN

Sequences:

>Translated_717_residues
MAGALAALVLAACGQGQVQKAEPRGFAAVDTARISAESAGNEWLTYGGTYDEQRHSKLTAINKENVGELGVAWTYDLATN
RGVESTPIVVDGVMYVTSAWSVVYALDAKTGEEKWVYDPGADRAVGVKACCDVVNRGVAVYDGKVYVGVIDGRLEALNAE
TGEVIWSKVTVDQEKPYTITGAPRVVNGKVLIGNGGAELGVRGYLSAYDTSSGDLVWRFYTVPNPKKQPDGAASDDAFVQ
VGNVTWGDEGAWTTDGGGGTVWDSIVYDEVNNQIIFGVGNGSPWNRTFRDPSAGDNLFLSSIVAVDLETGAYKWHFQTTP
GDNWDYTATQTIILADLPLGENGASRRVAMQAPKNGFFYVIDAATGEYISGDAYVPTNWATGLDENGRPIEVPEARYTKQ
PFEQTPGPLGGHNWHPMAFNPDEGLAYIPAQEIPQAYAEDSRFTARPVSWNTGIDFSAGVPPIAPPDVAKFLRASLKGRL
IAWDPIARAPRWSVEHENAWNGGVLSTAGGVVFQGKLGGEFVAYDAATGDKLWSHELKSGGASGPGTFMIDGEQYVTITT
GWGSAFALAAGFAYDEKVESTVGKVVTFKLGATGEIADSGLPPIDATPKAEAFGSMAVISEGAVHYARNCAVCHGPLGVS
SGVLPDLRWSAISANADAWKGVVLDGNLAANGMVSFADYITPDESEAIRAYVLTQAHAAVTPAEAAPAEESPPAEDN
>Mature_716_residues
AGALAALVLAACGQGQVQKAEPRGFAAVDTARISAESAGNEWLTYGGTYDEQRHSKLTAINKENVGELGVAWTYDLATNR
GVESTPIVVDGVMYVTSAWSVVYALDAKTGEEKWVYDPGADRAVGVKACCDVVNRGVAVYDGKVYVGVIDGRLEALNAET
GEVIWSKVTVDQEKPYTITGAPRVVNGKVLIGNGGAELGVRGYLSAYDTSSGDLVWRFYTVPNPKKQPDGAASDDAFVQV
GNVTWGDEGAWTTDGGGGTVWDSIVYDEVNNQIIFGVGNGSPWNRTFRDPSAGDNLFLSSIVAVDLETGAYKWHFQTTPG
DNWDYTATQTIILADLPLGENGASRRVAMQAPKNGFFYVIDAATGEYISGDAYVPTNWATGLDENGRPIEVPEARYTKQP
FEQTPGPLGGHNWHPMAFNPDEGLAYIPAQEIPQAYAEDSRFTARPVSWNTGIDFSAGVPPIAPPDVAKFLRASLKGRLI
AWDPIARAPRWSVEHENAWNGGVLSTAGGVVFQGKLGGEFVAYDAATGDKLWSHELKSGGASGPGTFMIDGEQYVTITTG
WGSAFALAAGFAYDEKVESTVGKVVTFKLGATGEIADSGLPPIDATPKAEAFGSMAVISEGAVHYARNCAVCHGPLGVSS
GVLPDLRWSAISANADAWKGVVLDGNLAANGMVSFADYITPDESEAIRAYVLTQAHAAVTPAEAAPAEESPPAEDN

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is not a substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=648, Percent_Identity=25.1543209876543, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF00034 Cytochrom_C; PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 75878; Mature: 75746

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGALAALVLAACGQGQVQKAEPRGFAAVDTARISAESAGNEWLTYGGTYDEQRHSKLTA
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHEEEECCCCCCCEEEECCCCCHHHHCEEEE
INKENVGELGVAWTYDLATNRGVESTPIVVDGVMYVTSAWSVVYALDAKTGEEKWVYDPG
ECCCCCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHCCCEEEEEEECCCCCCCEEECCC
ADRAVGVKACCDVVNRGVAVYDGKVYVGVIDGRLEALNAETGEVIWSKVTVDQEKPYTIT
CCCCCCHHHHHHHHHCCEEEECCEEEEEEECCEEEECCCCCCCEEEEEEEECCCCCEEEE
GAPRVVNGKVLIGNGGAELGVRGYLSAYDTSSGDLVWRFYTVPNPKKQPDGAASDDAFVQ
CCCEEEECEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
VGNVTWGDEGAWTTDGGGGTVWDSIVYDEVNNQIIFGVGNGSPWNRTFRDPSAGDNLFLS
ECCEEECCCCCEEECCCCCCHHHHHHEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEE
SIVAVDLETGAYKWHFQTTPGDNWDYTATQTIILADLPLGENGASRRVAMQAPKNGFFYV
EEEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEE
IDAATGEYISGDAYVPTNWATGLDENGRPIEVPEARYTKQPFEQTPGPLGGHNWHPMAFN
EECCCCCEECCCEEECCCCCCCCCCCCCEEECCCCHHCCCCHHHCCCCCCCCCCCCCEEC
PDEGLAYIPAQEIPQAYAEDSRFTARPVSWNTGIDFSAGVPPIAPPDVAKFLRASLKGRL
CCCCEEECCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
IAWDPIARAPRWSVEHENAWNGGVLSTAGGVVFQGKLGGEFVAYDAATGDKLWSHELKSG
EEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCC
GASGPGTFMIDGEQYVTITTGWGSAFALAAGFAYDEKVESTVGKVVTFKLGATGEIADSG
CCCCCCEEEECCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHCEEEEEEECCCCCCCCCC
LPPIDATPKAEAFGSMAVISEGAVHYARNCAVCHGPLGVSSGVLPDLRWSAISANADAWK
CCCCCCCCCHHHHCCEEEEECCCHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCE
GVVLDGNLAANGMVSFADYITPDESEAIRAYVLTQAHAAVTPAEAAPAEESPPAEDN
EEEEECCCCCCCCCHHHHHCCCCCHHHEEEEEEEEHHHHCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AGALAALVLAACGQGQVQKAEPRGFAAVDTARISAESAGNEWLTYGGTYDEQRHSKLTA
CHHHHHHHHHHCCCCCCCCCCCCCEEEEEHEEEECCCCCCCEEEECCCCCHHHHCEEEE
INKENVGELGVAWTYDLATNRGVESTPIVVDGVMYVTSAWSVVYALDAKTGEEKWVYDPG
ECCCCCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHCCCEEEEEEECCCCCCCEEECCC
ADRAVGVKACCDVVNRGVAVYDGKVYVGVIDGRLEALNAETGEVIWSKVTVDQEKPYTIT
CCCCCCHHHHHHHHHCCEEEECCEEEEEEECCEEEECCCCCCCEEEEEEEECCCCCEEEE
GAPRVVNGKVLIGNGGAELGVRGYLSAYDTSSGDLVWRFYTVPNPKKQPDGAASDDAFVQ
CCCEEEECEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
VGNVTWGDEGAWTTDGGGGTVWDSIVYDEVNNQIIFGVGNGSPWNRTFRDPSAGDNLFLS
ECCEEECCCCCEEECCCCCCHHHHHHEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEE
SIVAVDLETGAYKWHFQTTPGDNWDYTATQTIILADLPLGENGASRRVAMQAPKNGFFYV
EEEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEE
IDAATGEYISGDAYVPTNWATGLDENGRPIEVPEARYTKQPFEQTPGPLGGHNWHPMAFN
EECCCCCEECCCEEECCCCCCCCCCCCCEEECCCCHHCCCCHHHCCCCCCCCCCCCCEEC
PDEGLAYIPAQEIPQAYAEDSRFTARPVSWNTGIDFSAGVPPIAPPDVAKFLRASLKGRL
CCCCEEECCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
IAWDPIARAPRWSVEHENAWNGGVLSTAGGVVFQGKLGGEFVAYDAATGDKLWSHELKSG
EEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCC
GASGPGTFMIDGEQYVTITTGWGSAFALAAGFAYDEKVESTVGKVVTFKLGATGEIADSG
CCCCCCEEEECCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHCEEEEEEECCCCCCCCCC
LPPIDATPKAEAFGSMAVISEGAVHYARNCAVCHGPLGVSSGVLPDLRWSAISANADAWK
CCCCCCCCCHHHHCCEEEEECCCHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCE
GVVLDGNLAANGMVSFADYITPDESEAIRAYVLTQAHAAVTPAEAAPAEESPPAEDN
EEEEECCCCCCCCCHHHHHCCCCCHHHEEEEEEEEHHHHCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA