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The map label for this gene is yrbE [H]

Identifier: 114799793

GI number: 114799793

Start: 2278092

End: 2279216

Strand: Direct

Name: yrbE [H]

Synonym: HNE_2186

Alternate gene names: 114799793

Gene position: 2278092-2279216 (Clockwise)

Preceding gene: 114797478

Following gene: 114797632

Centisome position: 61.49

GC content: 57.69

Gene sequence:

>1125_bases
ATGACGCGGACTTACAACATTGCGCTAATCGGCACGGGCTATATCGGAAAGACCCACGCTATCGCCTATCAGGGCGTCAA
TGTCGTTTTCCCCGAGACACCCCGGCTCGTGAGAAAGCTGGTCATAGACATCAATGAAGAAGCCGGACGCACCTTCGCCA
ACCAGTTCGGGTTTGAAGGCTTCTCTACCAACTGGCGGGACGCCATCACGCGCACCGATATCGACATCGTCGCGATTGCA
ACCCCGAACTATCTGCATGCGGAGATGGCAATTGCTGCCTTGGAGCACGGCAAGCATGTCTATTGCGAAAAGCCCCTGGC
CGTCACGGTCGAAGACGCCGCCGCCATGGCTGCGGCCGCCGCCCTTTACCCTGGCCGGACGCTTGTCGGTTACAACTATC
TCTGCAACCCGATTGTTCAACTCGCAAAGCAGCTCATATCCGAAGGCCGGATCGGCAAGCCCCTCTTCTTCCGCGGCGTG
AATGACGAAGACTATATGGCCGATCCGCAGACGCCCCACAGCTGGCGCTGCGAACGCCACAAGGCTGGCCCAGGCACCCT
GGGTGACCTCGCCACTCATCTTATCAGCATGTCCGAGTTCCTTATGGGCGAAATCACGGACGTTTCAGGTCATCTGTACA
CGGCACACACAACGCGTCCCTCTCCATCAGATGTCGAGGTGCAGCTACCTGTGGAGAATGACGACATCGTCTCGATGGTC
GTATCCTACAAAAGCGGCGCGCGCGGCGAACTCTCCTCCAGCCGTATAGCATGGGGCCGCAAGAACCGCCTCGCCTTCGA
AATTCATGGGGAGCGAGGTTCGATCCTTTTTGATCAGGAACGCCTTAACGAGCTTGAACTCTACTCATCGGGCGGCCCGG
CCCATAGCAACGGTTTCCAGAAGATCCTGGCCGGCCCTGCGCATGAGCCCTACGGCGCGTTCATCAAATCGACAGGTCAC
CAGCTAGGCTTCAACGACCTCAAGATAATCGAAGTGCGCAACCTTCTTGTTGGCCTCGAAAGCGAAAGCCGATCCTATCC
GGCATTCGAGGATGCCCTACGCGTCGAGCAGGTCATCAACAGCGTCCTCCGCTCAGCAGACGCCGGCCAATCAGTAAATA
TCTAA

Upstream 100 bases:

>100_bases
GATCCCGCACACGAATGGATCATCAAGAAATAGCGCGCCCGGGCCAGCGACCTGCCCGCCCTCCAAACTTCCCAGATCAA
TCGGCATTCAGGACCATAGC

Downstream 100 bases:

>100_bases
CCTTTCGCCTGCGGTGCTTGAGACAGGAGCTGAGTGACACCATTCGGAGAATAGCGGCTGTCTGCGGCAGCAACACGAAG
ACGGCAGCCTCGCGCCAAAC

Product: NAD-binding oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTRTYNIALIGTGYIGKTHAIAYQGVNVVFPETPRLVRKLVIDINEEAGRTFANQFGFEGFSTNWRDAITRTDIDIVAIA
TPNYLHAEMAIAALEHGKHVYCEKPLAVTVEDAAAMAAAAALYPGRTLVGYNYLCNPIVQLAKQLISEGRIGKPLFFRGV
NDEDYMADPQTPHSWRCERHKAGPGTLGDLATHLISMSEFLMGEITDVSGHLYTAHTTRPSPSDVEVQLPVENDDIVSMV
VSYKSGARGELSSSRIAWGRKNRLAFEIHGERGSILFDQERLNELELYSSGGPAHSNGFQKILAGPAHEPYGAFIKSTGH
QLGFNDLKIIEVRNLLVGLESESRSYPAFEDALRVEQVINSVLRSADAGQSVNI

Sequences:

>Translated_374_residues
MTRTYNIALIGTGYIGKTHAIAYQGVNVVFPETPRLVRKLVIDINEEAGRTFANQFGFEGFSTNWRDAITRTDIDIVAIA
TPNYLHAEMAIAALEHGKHVYCEKPLAVTVEDAAAMAAAAALYPGRTLVGYNYLCNPIVQLAKQLISEGRIGKPLFFRGV
NDEDYMADPQTPHSWRCERHKAGPGTLGDLATHLISMSEFLMGEITDVSGHLYTAHTTRPSPSDVEVQLPVENDDIVSMV
VSYKSGARGELSSSRIAWGRKNRLAFEIHGERGSILFDQERLNELELYSSGGPAHSNGFQKILAGPAHEPYGAFIKSTGH
QLGFNDLKIIEVRNLLVGLESESRSYPAFEDALRVEQVINSVLRSADAGQSVNI
>Mature_373_residues
TRTYNIALIGTGYIGKTHAIAYQGVNVVFPETPRLVRKLVIDINEEAGRTFANQFGFEGFSTNWRDAITRTDIDIVAIAT
PNYLHAEMAIAALEHGKHVYCEKPLAVTVEDAAAMAAAAALYPGRTLVGYNYLCNPIVQLAKQLISEGRIGKPLFFRGVN
DEDYMADPQTPHSWRCERHKAGPGTLGDLATHLISMSEFLMGEITDVSGHLYTAHTTRPSPSDVEVQLPVENDDIVSMVV
SYKSGARGELSSSRIAWGRKNRLAFEIHGERGSILFDQERLNELELYSSGGPAHSNGFQKILAGPAHEPYGAFIKSTGHQ
LGFNDLKIIEVRNLLVGLESESRSYPAFEDALRVEQVINSVLRSADAGQSVNI

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=289, Percent_Identity=27.681660899654, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081947, Length=203, Percent_Identity=30.5418719211823, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581117, Length=230, Percent_Identity=27.8260869565217, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41046; Mature: 40915

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTYNIALIGTGYIGKTHAIAYQGVNVVFPETPRLVRKLVIDINEEAGRTFANQFGFEG
CCEEEEEEEEECCCCCCCEEEEECCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
FSTNWRDAITRTDIDIVAIATPNYLHAEMAIAALEHGKHVYCEKPLAVTVEDAAAMAAAA
CCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHH
ALYPGRTLVGYNYLCNPIVQLAKQLISEGRIGKPLFFRGVNDEDYMADPQTPHSWRCERH
HHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
KAGPGTLGDLATHLISMSEFLMGEITDVSGHLYTAHTTRPSPSDVEVQLPVENDDIVSMV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHH
VSYKSGARGELSSSRIAWGRKNRLAFEIHGERGSILFDQERLNELELYSSGGPAHSNGFQ
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECHHHCCCEEEECCCCCCCCCHHH
KILAGPAHEPYGAFIKSTGHQLGFNDLKIIEVRNLLVGLESESRSYPAFEDALRVEQVIN
HHHCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEHHHEECCCCCCCCCCHHHHHHHHHHHH
SVLRSADAGQSVNI
HHHHCCCCCCCCCC
>Mature Secondary Structure 
TRTYNIALIGTGYIGKTHAIAYQGVNVVFPETPRLVRKLVIDINEEAGRTFANQFGFEG
CEEEEEEEEECCCCCCCEEEEECCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
FSTNWRDAITRTDIDIVAIATPNYLHAEMAIAALEHGKHVYCEKPLAVTVEDAAAMAAAA
CCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHH
ALYPGRTLVGYNYLCNPIVQLAKQLISEGRIGKPLFFRGVNDEDYMADPQTPHSWRCERH
HHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
KAGPGTLGDLATHLISMSEFLMGEITDVSGHLYTAHTTRPSPSDVEVQLPVENDDIVSMV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHH
VSYKSGARGELSSSRIAWGRKNRLAFEIHGERGSILFDQERLNELELYSSGGPAHSNGFQ
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECHHHCCCEEEECCCCCCCCCHHH
KILAGPAHEPYGAFIKSTGHQLGFNDLKIIEVRNLLVGLESESRSYPAFEDALRVEQVIN
HHHCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEHHHEECCCCCCCCCCHHHHHHHHHHHH
SVLRSADAGQSVNI
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]