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The map label for this gene is iolB [H]

Identifier: 114797478

GI number: 114797478

Start: 2277224

End: 2278024

Strand: Direct

Name: iolB [H]

Synonym: HNE_2185

Alternate gene names: 114797478

Gene position: 2277224-2278024 (Clockwise)

Preceding gene: 114798293

Following gene: 114799793

Centisome position: 61.46

GC content: 59.8

Gene sequence:

>801_bases
ATGCCTGATCTGCGCGTCAAAAGCGGGACACCAGCCAGCGATGGCTGCGTCCTATCTATCACCCCCGAATCGGCAGGTTG
GGACCATGTGGGCTTCGCTGTTCACAGGCTCGAAGAAGGCAAGGGTTTTGAATCCGCCGCCTCATCCCGGGAAACCTGCC
TGGTCATTCTGACCGGCACAGCACGCGTCTCCGTGGGAACCGAAGTCTTTGCGCACCTTGGGGAGCGCAAAACCGTCTTT
GAGGGTCCGCCGGCGGCGGTCTACATTCCGGCAGGCGAACGCTATTCCGTCACCGCAGAAATGCCGCTTGAAGTCGCCGT
CTGTTCGGCGCCCGGGGGCGGAAATCATCCCGCCCGCGTCATTGCACCTGGCAGCATTGAGAAGGAAATCCGCGGCAAGG
CCGCTAACACCCGCTACGTGCAGGATATCCTGTCTGACCGTGATCCGGCCCACAGTCTCCTGGTCGTTGAGGTCATCACG
CCGGGCGGCAACTGGTCGAGTTATCCGCCCCACAAGCATGACACCGACACACTCCCTGAAGAATCCGCGCTGGAAGAGAC
CTATTATCACCGGCTGAACCCGCCCCAGGGCTTTGCCGTACAGCGTGTGTATACTGACGACCGCAGTCTTGATGAGACCG
TGTCGGTAGAAGATGGCGACTGCGTGATGGTTCCCGCCGGATACCACCCCGTCGGGGCGCCTTATGGCTACGATCTCTAC
TATCTCAACGTCATGGCGGGTGCGAAACGGAAATGGGTATTCCGCAACGATCCCGCACACGAATGGATCATCAAGAAATA
G

Upstream 100 bases:

>100_bases
CCCGCCAAGGCCGATCCCCGGACTTATGCGAGCATGGGCCTCGCCCATGTGAAAAACTGTATCGAGCGTAGTTATAACAA
GGACAAAGTGGAGTCGGCTG

Downstream 100 bases:

>100_bases
CGCGCCCGGGCCAGCGACCTGCCCGCCCTCCAAACTTCCCAGATCAATCGGCATTCAGGACCATAGCATGACGCGGACTT
ACAACATTGCGCTAATCGGC

Product: myo-inositol catabolism protein IolB

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPDLRVKSGTPASDGCVLSITPESAGWDHVGFAVHRLEEGKGFESAASSRETCLVILTGTARVSVGTEVFAHLGERKTVF
EGPPAAVYIPAGERYSVTAEMPLEVAVCSAPGGGNHPARVIAPGSIEKEIRGKAANTRYVQDILSDRDPAHSLLVVEVIT
PGGNWSSYPPHKHDTDTLPEESALEETYYHRLNPPQGFAVQRVYTDDRSLDETVSVEDGDCVMVPAGYHPVGAPYGYDLY
YLNVMAGAKRKWVFRNDPAHEWIIKK

Sequences:

>Translated_266_residues
MPDLRVKSGTPASDGCVLSITPESAGWDHVGFAVHRLEEGKGFESAASSRETCLVILTGTARVSVGTEVFAHLGERKTVF
EGPPAAVYIPAGERYSVTAEMPLEVAVCSAPGGGNHPARVIAPGSIEKEIRGKAANTRYVQDILSDRDPAHSLLVVEVIT
PGGNWSSYPPHKHDTDTLPEESALEETYYHRLNPPQGFAVQRVYTDDRSLDETVSVEDGDCVMVPAGYHPVGAPYGYDLY
YLNVMAGAKRKWVFRNDPAHEWIIKK
>Mature_265_residues
PDLRVKSGTPASDGCVLSITPESAGWDHVGFAVHRLEEGKGFESAASSRETCLVILTGTARVSVGTEVFAHLGERKTVFE
GPPAAVYIPAGERYSVTAEMPLEVAVCSAPGGGNHPARVIAPGSIEKEIRGKAANTRYVQDILSDRDPAHSLLVVEVITP
GGNWSSYPPHKHDTDTLPEESALEETYYHRLNPPQGFAVQRVYTDDRSLDETVSVEDGDCVMVPAGYHPVGAPYGYDLYY
LNVMAGAKRKWVFRNDPAHEWIIKK

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 28933; Mature: 28801

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLRVKSGTPASDGCVLSITPESAGWDHVGFAVHRLEEGKGFESAASSRETCLVILTGT
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHEEEEHHCCCCHHHHCCCCCEEEEEEECC
ARVSVGTEVFAHLGERKTVFEGPPAAVYIPAGERYSVTAEMPLEVAVCSAPGGGNHPARV
EEEEHHHHHHHHCCCCCEEECCCCCEEEEECCCCEEEEECCCEEEEEEECCCCCCCCEEE
IAPGSIEKEIRGKAANTRYVQDILSDRDPAHSLLVVEVITPGGNWSSYPPHKHDTDTLPE
EECCCCHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
ESALEETYYHRLNPPQGFAVQRVYTDDRSLDETVSVEDGDCVMVPAGYHPVGAPYGYDLY
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
YLNVMAGAKRKWVFRNDPAHEWIIKK
EEEEECCCCEEEEEECCCCCCEEECC
>Mature Secondary Structure 
PDLRVKSGTPASDGCVLSITPESAGWDHVGFAVHRLEEGKGFESAASSRETCLVILTGT
CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHEEEEHHCCCCHHHHCCCCCEEEEEEECC
ARVSVGTEVFAHLGERKTVFEGPPAAVYIPAGERYSVTAEMPLEVAVCSAPGGGNHPARV
EEEEHHHHHHHHCCCCCEEECCCCCEEEEECCCCEEEEECCCEEEEEEECCCCCCCCEEE
IAPGSIEKEIRGKAANTRYVQDILSDRDPAHSLLVVEVITPGGNWSSYPPHKHDTDTLPE
EECCCCHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
ESALEETYYHRLNPPQGFAVQRVYTDDRSLDETVSVEDGDCVMVPAGYHPVGAPYGYDLY
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
YLNVMAGAKRKWVFRNDPAHEWIIKK
EEEEECCCCEEEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA