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The map label for this gene is yoeA [H]

Identifier: 114799781

GI number: 114799781

Start: 2401828

End: 2403303

Strand: Direct

Name: yoeA [H]

Synonym: HNE_2304

Alternate gene names: 114799781

Gene position: 2401828-2403303 (Clockwise)

Preceding gene: 114798896

Following gene: 114798590

Centisome position: 64.83

GC content: 65.51

Gene sequence:

>1476_bases
ATGCAAAAGAAGAATGACCTCACCACAGGCGCCATCGGCCCGGCGCTGATCGCCTTTACGCTGCCCACGCTCGCCGCCTC
GATCCTGCAATCGGCCAACGGTTCGATCGACACAATCTGGGTCGGCCGCCTGCTGGGCGAAACGGCTGTTGCCGCCACCA
CGAACGGAAATCTCGTCGTCTTCCTGCTCACGGCCTTCGTCTTCGGTTTCGGCATGGCGTCCACCATCCTCATCGGCCAG
TCGATGGGCCGCGATGATGTCGTCGCTGCCCGCCGCGTCGTCGGCACGGTCGTGGGCTCGTTTTTGCCTGTCTCGACCCT
TCTGGGAATTGCCGGCTGGTTTCTTTCACCTGCCCTGCTTGCCGTGCTGGATACCCCCGCAGAGGTCGTCCCGCTGGCGC
TCGATTTCCTTCAGATCGTCTTCCTCGCCCTGCCCGCCATCCTCATCATGACCATGCTGATGATGGCCCTGCGCGGGGCG
GGGGACGCGATGACGCCGCTGATCTTCATGGCCGTCGCCGTGGTGCTCTGCGCGGTGCTGAACCCTTTCTTCATCCTCGG
CATCGGCCCCTTCCCGCGCCTTGGCATCGGCGGCTCGGCCCTCGCGCTGACGCTTGCCAACTATATCAGCCTCATCGCCA
TGCTGATCTACATCTACCGGCGCGACCTGCCGCTGCGCCTGCGCGGGGCAGAGCTTCGCTGGCTGATGCCGGACCTCCCC
ATCCTGCGCCTGATGGTCGTCAAAGGCTTCCCGATGGGCCTGCAGATGATCGTCATCTCCGGCTCGCTGCTCGCCATGAT
GTCGCTCGTCAACCGGCAGGGCGTCGACACCACCGCCGCCTTCGGGGCCACCCAGCAGCTTTGGACCTATGTGCAGATGC
CCGCCATGGCCATCGGCGCCGCCGTCAGCGCCATGGCCGCCCAGAATATCGGCGCCGGGCGCTGGGACCGCGTGGACGAG
ATCACCCGCCTCGGGATCATCTATAACCTCCTGCTCACCGGCGCGCTGATCGCGCTGCTCCTCATGGCAGACCGCGCCGC
AATGATGGTCTTCCTCGGCAGCGAGAGCAACGCCGTCGCCATCGGCCAGCACATCACCCGGCTCGCCTCCTGGGGCTTCC
TGCCGTTTGCCGTCACGATGGTTCTCTTCGCCACCGTACGCGCGAACGGCCAGGTGTTCTGGCCGCTGATCATCCTCTTC
ATCTCCATGTTCCCCGTGCGCCTCGGCTTTGCTTACGGGCTGCAGGGCATGCTCGGCGCCGACGCGATCTGGTGGAGTTT
CCCGGCAGGCATGATCGTCACTATGCTGCTTGCTATCGTGCTTTACCGCTATGGCGGCTGGCGCAACGAGCGCGAGATGC
GCGTGCCAGATGGCGACACCGCAGAGGCCTCCGCCCTCGCCGCCAGCGTGCCGGCCGAAACCACCTCGTCGATCACATCA
GCCACCCATTCACGCCGCCGCCGGGACGAGCCCTAA

Upstream 100 bases:

>100_bases
CCTCTCCCGCTCCAAGAACTCCCCCTTCGACGGCCGCCGCCTGCAAGGCCGCGTCATGCGGACGTTCGTGGGCGGGGAAA
GCGTCTTCAAGCGGTAGGGC

Downstream 100 bases:

>100_bases
GCCCCCGCAGCAGGCCATATTGTTCGCGCGCCCATTTGCGCGGATAAAGGCGTTCGTGCCCGCCAATCAGGACCCGCCGA
ATGCCAACGACGCCAGACCT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MQKKNDLTTGAIGPALIAFTLPTLAASILQSANGSIDTIWVGRLLGETAVAATTNGNLVVFLLTAFVFGFGMASTILIGQ
SMGRDDVVAARRVVGTVVGSFLPVSTLLGIAGWFLSPALLAVLDTPAEVVPLALDFLQIVFLALPAILIMTMLMMALRGA
GDAMTPLIFMAVAVVLCAVLNPFFILGIGPFPRLGIGGSALALTLANYISLIAMLIYIYRRDLPLRLRGAELRWLMPDLP
ILRLMVVKGFPMGLQMIVISGSLLAMMSLVNRQGVDTTAAFGATQQLWTYVQMPAMAIGAAVSAMAAQNIGAGRWDRVDE
ITRLGIIYNLLLTGALIALLLMADRAAMMVFLGSESNAVAIGQHITRLASWGFLPFAVTMVLFATVRANGQVFWPLIILF
ISMFPVRLGFAYGLQGMLGADAIWWSFPAGMIVTMLLAIVLYRYGGWRNEREMRVPDGDTAEASALAASVPAETTSSITS
ATHSRRRRDEP

Sequences:

>Translated_491_residues
MQKKNDLTTGAIGPALIAFTLPTLAASILQSANGSIDTIWVGRLLGETAVAATTNGNLVVFLLTAFVFGFGMASTILIGQ
SMGRDDVVAARRVVGTVVGSFLPVSTLLGIAGWFLSPALLAVLDTPAEVVPLALDFLQIVFLALPAILIMTMLMMALRGA
GDAMTPLIFMAVAVVLCAVLNPFFILGIGPFPRLGIGGSALALTLANYISLIAMLIYIYRRDLPLRLRGAELRWLMPDLP
ILRLMVVKGFPMGLQMIVISGSLLAMMSLVNRQGVDTTAAFGATQQLWTYVQMPAMAIGAAVSAMAAQNIGAGRWDRVDE
ITRLGIIYNLLLTGALIALLLMADRAAMMVFLGSESNAVAIGQHITRLASWGFLPFAVTMVLFATVRANGQVFWPLIILF
ISMFPVRLGFAYGLQGMLGADAIWWSFPAGMIVTMLLAIVLYRYGGWRNEREMRVPDGDTAEASALAASVPAETTSSITS
ATHSRRRRDEP
>Mature_491_residues
MQKKNDLTTGAIGPALIAFTLPTLAASILQSANGSIDTIWVGRLLGETAVAATTNGNLVVFLLTAFVFGFGMASTILIGQ
SMGRDDVVAARRVVGTVVGSFLPVSTLLGIAGWFLSPALLAVLDTPAEVVPLALDFLQIVFLALPAILIMTMLMMALRGA
GDAMTPLIFMAVAVVLCAVLNPFFILGIGPFPRLGIGGSALALTLANYISLIAMLIYIYRRDLPLRLRGAELRWLMPDLP
ILRLMVVKGFPMGLQMIVISGSLLAMMSLVNRQGVDTTAAFGATQQLWTYVQMPAMAIGAAVSAMAAQNIGAGRWDRVDE
ITRLGIIYNLLLTGALIALLLMADRAAMMVFLGSESNAVAIGQHITRLASWGFLPFAVTMVLFATVRANGQVFWPLIILF
ISMFPVRLGFAYGLQGMLGADAIWWSFPAGMIVTMLLAIVLYRYGGWRNEREMRVPDGDTAEASALAASVPAETTSSITS
ATHSRRRRDEP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=395, Percent_Identity=24.0506329113924, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52530; Mature: 52530

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKNDLTTGAIGPALIAFTLPTLAASILQSANGSIDTIWVGRLLGETAVAATTNGNLVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCHHEEEECCCCCHH
FLLTAFVFGFGMASTILIGQSMGRDDVVAARRVVGTVVGSFLPVSTLLGIAGWFLSPALL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLDTPAEVVPLALDFLQIVFLALPAILIMTMLMMALRGAGDAMTPLIFMAVAVVLCAVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NPFFILGIGPFPRLGIGGSALALTLANYISLIAMLIYIYRRDLPLRLRGAELRWLMPDLP
CCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCHH
ILRLMVVKGFPMGLQMIVISGSLLAMMSLVNRQGVDTTAAFGATQQLWTYVQMPAMAIGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
AVSAMAAQNIGAGRWDRVDEITRLGIIYNLLLTGALIALLLMADRAAMMVFLGSESNAVA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEH
IGQHITRLASWGFLPFAVTMVLFATVRANGQVFWPLIILFISMFPVRLGFAYGLQGMLGA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHCC
DAIWWSFPAGMIVTMLLAIVLYRYGGWRNEREMRVPDGDTAEASALAASVPAETTSSITS
CHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ATHSRRRRDEP
HHHHHHCCCCC
>Mature Secondary Structure
MQKKNDLTTGAIGPALIAFTLPTLAASILQSANGSIDTIWVGRLLGETAVAATTNGNLVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCHHEEEECCCCCHH
FLLTAFVFGFGMASTILIGQSMGRDDVVAARRVVGTVVGSFLPVSTLLGIAGWFLSPALL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLDTPAEVVPLALDFLQIVFLALPAILIMTMLMMALRGAGDAMTPLIFMAVAVVLCAVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NPFFILGIGPFPRLGIGGSALALTLANYISLIAMLIYIYRRDLPLRLRGAELRWLMPDLP
CCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCHH
ILRLMVVKGFPMGLQMIVISGSLLAMMSLVNRQGVDTTAAFGATQQLWTYVQMPAMAIGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
AVSAMAAQNIGAGRWDRVDEITRLGIIYNLLLTGALIALLLMADRAAMMVFLGSESNAVA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEH
IGQHITRLASWGFLPFAVTMVLFATVRANGQVFWPLIILFISMFPVRLGFAYGLQGMLGA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHCC
DAIWWSFPAGMIVTMLLAIVLYRYGGWRNEREMRVPDGDTAEASALAASVPAETTSSITS
CHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ATHSRRRRDEP
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]