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The map label for this gene is ltaE [H]

Identifier: 114799707

GI number: 114799707

Start: 467922

End: 468959

Strand: Direct

Name: ltaE [H]

Synonym: HNE_0475

Alternate gene names: 114799707

Gene position: 467922-468959 (Clockwise)

Preceding gene: 114797330

Following gene: 114799068

Centisome position: 12.63

GC content: 66.67

Gene sequence:

>1038_bases
ATGAACTTCTCTTCCGACACGGCGGCGCCGGCGCATCCTTCCGTGCTGGAGGCCATGGGGCGGGCCAATGACGGGGCGGA
GGCGAGCTATGGCGCCGACAGGATTACCGCGCGGCTGCGCGCGCGCCTCGCCGAGGTGTTCGAAACAGACGACTTTGACT
TCTGGCTGACGGCATCGGGCACGGCGTCCAACGCGCTGGCGCTTTCCTGCTTCTGCCCGCCGACCCATTCGATCCTCTGC
CACCATGAAGCGCATATCCAGATGGATGAGCGCGGGGCGGTGGAGTTTTTCACCGGCGGGGGGCGGCTGGCGCTGTTGCC
GGGCACGGGCGCGAAGATCGATTATGATGTGTTTGCGGACTATCTGGGAAATGTGGACCCGAGCTTTGTGCATGGCACGC
CGCCGGCGGTCCTCTCGCTGACGAACCTCACTGAATGCGGCATGGCTTATTCGCCCGATGAAGTGGCGCGGTTTGCGCGC
CGCGCGAAGGGCGGAAAACTGGCCGTGCATATGGACGGGGCGCGGTTTGCCAATGCGCTGGTGCACACGGGCGCAAGCCC
GGCGCAGATGAGCTGGCAGGCCGGCGTGGATGTGCTGACCCTGGGGTTGACGAAAACCGGCGCGGCGGGGTGCGAGATCA
TCCTCCTTTTTGGCGCGGCCAAGGCCAAGGGTGGGGAGCTGCGCGCGCGGGCCAAACGGTCCGGCCACATGCCGCCGAAG
ATGCGCTTCCTGGCGGCGCAGGCCGAGGCGATGCTGGAGGGCGGGTTGTGGCTGACGTTGGCCGCTCATGCCAATGCGAT
GGCCGCGCGCCTGGCCGGCGTGTTCACCGGGGCGGGCTATGAGCTTGCCTGGGATGTTCAGGGTAATGAGGTGTTTGCGC
TGCTGGACCCGCGCGCGGTGCAGGATCTGCAGGAAGACAATGCGCGCTTCTATGCCGACTGGCCGGGCGGATCGAGCCGG
TTTGTCTGCTCCTGGGCCACGACCGAGGCAGAGATTGCCGACCTGAAGGACACGCTGGTCCGGCCGCCGCGGATTTAG

Upstream 100 bases:

>100_bases
CTGATTTCTGCCTCCAGCGTGACCGGCCAGATGATTGCGTCTGATGGCGGGCAGCATCTGATGTGGCAGACGCCGGACAC
CCAATTTTGAAGGAACTCCT

Downstream 100 bases:

>100_bases
GGGCCAACCCGCGTCATTTCATCTGCGATCTGCGCCAGAAGGTCTGCGGCGGGGAGCGCCCGGTGAAGGGGCGCGCCCTG
GCCAGCCCATTGGGCGCCGT

Product: threonine aldolase, low-specificity

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNFSSDTAAPAHPSVLEAMGRANDGAEASYGADRITARLRARLAEVFETDDFDFWLTASGTASNALALSCFCPPTHSILC
HHEAHIQMDERGAVEFFTGGGRLALLPGTGAKIDYDVFADYLGNVDPSFVHGTPPAVLSLTNLTECGMAYSPDEVARFAR
RAKGGKLAVHMDGARFANALVHTGASPAQMSWQAGVDVLTLGLTKTGAAGCEIILLFGAAKAKGGELRARAKRSGHMPPK
MRFLAAQAEAMLEGGLWLTLAAHANAMAARLAGVFTGAGYELAWDVQGNEVFALLDPRAVQDLQEDNARFYADWPGGSSR
FVCSWATTEAEIADLKDTLVRPPRI

Sequences:

>Translated_345_residues
MNFSSDTAAPAHPSVLEAMGRANDGAEASYGADRITARLRARLAEVFETDDFDFWLTASGTASNALALSCFCPPTHSILC
HHEAHIQMDERGAVEFFTGGGRLALLPGTGAKIDYDVFADYLGNVDPSFVHGTPPAVLSLTNLTECGMAYSPDEVARFAR
RAKGGKLAVHMDGARFANALVHTGASPAQMSWQAGVDVLTLGLTKTGAAGCEIILLFGAAKAKGGELRARAKRSGHMPPK
MRFLAAQAEAMLEGGLWLTLAAHANAMAARLAGVFTGAGYELAWDVQGNEVFALLDPRAVQDLQEDNARFYADWPGGSSR
FVCSWATTEAEIADLKDTLVRPPRI
>Mature_345_residues
MNFSSDTAAPAHPSVLEAMGRANDGAEASYGADRITARLRARLAEVFETDDFDFWLTASGTASNALALSCFCPPTHSILC
HHEAHIQMDERGAVEFFTGGGRLALLPGTGAKIDYDVFADYLGNVDPSFVHGTPPAVLSLTNLTECGMAYSPDEVARFAR
RAKGGKLAVHMDGARFANALVHTGASPAQMSWQAGVDVLTLGLTKTGAAGCEIILLFGAAKAKGGELRARAKRSGHMPPK
MRFLAAQAEAMLEGGLWLTLAAHANAMAARLAGVFTGAGYELAWDVQGNEVFALLDPRAVQDLQEDNARFYADWPGGSSR
FVCSWATTEAEIADLKDTLVRPPRI

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=328, Percent_Identity=25.3048780487805, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36687; Mature: 36687

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSSDTAAPAHPSVLEAMGRANDGAEASYGADRITARLRARLAEVFETDDFDFWLTASG
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
TASNALALSCFCPPTHSILCHHEAHIQMDERGAVEFFTGGGRLALLPGTGAKIDYDVFAD
CCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCEEEEECCCEEEEECCCCCEEEHHHHHH
YLGNVDPSFVHGTPPAVLSLTNLTECGMAYSPDEVARFARRAKGGKLAVHMDGARFANAL
HHCCCCCCEECCCCHHEEEECCHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHH
VHTGASPAQMSWQAGVDVLTLGLTKTGAAGCEIILLFGAAKAKGGELRARAKRSGHMPPK
HHCCCCCCCCHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCCHH
MRFLAAQAEAMLEGGLWLTLAAHANAMAARLAGVFTGAGYELAWDVQGNEVFALLDPRAV
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHH
QDLQEDNARFYADWPGGSSRFVCSWATTEAEIADLKDTLVRPPRI
HHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFSSDTAAPAHPSVLEAMGRANDGAEASYGADRITARLRARLAEVFETDDFDFWLTASG
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
TASNALALSCFCPPTHSILCHHEAHIQMDERGAVEFFTGGGRLALLPGTGAKIDYDVFAD
CCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCEEEEECCCEEEEECCCCCEEEHHHHHH
YLGNVDPSFVHGTPPAVLSLTNLTECGMAYSPDEVARFARRAKGGKLAVHMDGARFANAL
HHCCCCCCEECCCCHHEEEECCHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHH
VHTGASPAQMSWQAGVDVLTLGLTKTGAAGCEIILLFGAAKAKGGELRARAKRSGHMPPK
HHCCCCCCCCHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCCHH
MRFLAAQAEAMLEGGLWLTLAAHANAMAARLAGVFTGAGYELAWDVQGNEVFALLDPRAV
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHH
QDLQEDNARFYADWPGGSSRFVCSWATTEAEIADLKDTLVRPPRI
HHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]