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The map label for this gene is ahpD

Identifier: 114799646

GI number: 114799646

Start: 3204224

End: 3204766

Strand: Reverse

Name: ahpD

Synonym: HNE_3034

Alternate gene names: 114799646

Gene position: 3204766-3204224 (Counterclockwise)

Preceding gene: 114797286

Following gene: 114800447

Centisome position: 86.5

GC content: 63.72

Gene sequence:

>543_bases
ATGTCGCTTGAAACCCTGAAGACCCTGATCCCCGATTACGCCAAGGACATCCGTCTCAATATCGGCTCCCTGGCGAATGA
AACGATCCTGTCCGAGCAGCAGAAATATGGCTGCTATCTCGCCTCGGCGCACGCCGTTGGCGAAGCGCAGACCCTGCGCG
CCATTGAAGCAGAAGCGCGTGGCAAGCTGTCGGTCGAAGCGCTGAACGCGGCCAAGGCGGCGAGCGCCATCATGGGCATG
AACAATGTCTATTACCGCGCCACGCACCTTGTCTCGAACACGACCTATACGACGATGCCGGCGCGCCTGCGGATGAACGT
CATCGGTAATCCGGGCGTCGAGAAGGTGGACTTCGAGCTGTGGTCGCTGGCGGTGTCGGCGATCAATGGCTGCGGCATGT
GCCTGGACGCGCATGAGGCCGAGCTGCGCAAGCATGGCGTGACCAGCGAGCAGATCCAGGCCGCGATCCGGATTGGCGCG
GTGGTGAACGCTGCGGCGCGGGTGCTGGCAGCCGAAGCGGCGCTGGCGGCAGAGCCGGCCTGA

Upstream 100 bases:

>100_bases
CCCTGCGCCCGCCCCGCGTCCCCCCACTCATGGTGGGCGCGGCCTGGGACCGGCTGGTTATTCCCTTATTTCATTCCCGA
TTTCTCAGAGGAGCGCGCTC

Downstream 100 bases:

>100_bases
GCGGTTTCCGGTTCCAGATCATGACCAGAACATGGGAGCCCCTGGGCCTTTATGGGCCTGGGGGCTCTTTTTTGCCGAAA
TGCGGGGATTCCGGGCGTCA

Product: alkylhydroperoxidase

Products: NA

Alternate protein names: Alkylhydroperoxidase AhpD

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSLETLKTLIPDYAKDIRLNIGSLANETILSEQQKYGCYLASAHAVGEAQTLRAIEAEARGKLSVEALNAAKAASAIMGM
NNVYYRATHLVSNTTYTTMPARLRMNVIGNPGVEKVDFELWSLAVSAINGCGMCLDAHEAELRKHGVTSEQIQAAIRIGA
VVNAAARVLAAEAALAAEPA

Sequences:

>Translated_180_residues
MSLETLKTLIPDYAKDIRLNIGSLANETILSEQQKYGCYLASAHAVGEAQTLRAIEAEARGKLSVEALNAAKAASAIMGM
NNVYYRATHLVSNTTYTTMPARLRMNVIGNPGVEKVDFELWSLAVSAINGCGMCLDAHEAELRKHGVTSEQIQAAIRIGA
VVNAAARVLAAEAALAAEPA
>Mature_179_residues
SLETLKTLIPDYAKDIRLNIGSLANETILSEQQKYGCYLASAHAVGEAQTLRAIEAEARGKLSVEALNAAKAASAIMGMN
NVYYRATHLVSNTTYTTMPARLRMNVIGNPGVEKVDFELWSLAVSAINGCGMCLDAHEAELRKHGVTSEQIQAAIRIGAV
VNAAARVLAAEAALAAEPA

Specific function: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity

COG id: COG2128

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AhpD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AHPD_HYPNA (Q0BXT2)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761711.1
- ProteinModelPortal:   Q0BXT2
- SMR:   Q0BXT2
- STRING:   Q0BXT2
- PeroxiBase:   4635
- GeneID:   4290286
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_3034
- NMPDR:   fig|228405.5.peg.2909
- TIGR:   HNE_3034
- eggNOG:   COG2128
- HOGENOM:   HBG414634
- OMA:   PEYAKDL
- ProtClustDB:   CLSK858644
- BioCyc:   HNEP81032:HNE_3034-MONOMER
- HAMAP:   MF_01676
- InterPro:   IPR004674
- InterPro:   IPR004675
- InterPro:   IPR003779
- TIGRFAMs:   TIGR00777
- TIGRFAMs:   TIGR00778

Pfam domain/function: PF02627 CMD

EC number: =1.11.1.15

Molecular weight: Translated: 19114; Mature: 18983

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 131-131 ACT_SITE 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLETLKTLIPDYAKDIRLNIGSLANETILSEQQKYGCYLASAHAVGEAQTLRAIEAEAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCHHHHHHHHHHHHC
GKLSVEALNAAKAASAIMGMNNVYYRATHLVSNTTYTTMPARLRMNVIGNPGVEKVDFEL
CCEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHH
WSLAVSAINGCGMCLDAHEAELRKHGVTSEQIQAAIRIGAVVNAAARVLAAEAALAAEPA
HHHHHHHHCCCCCEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLETLKTLIPDYAKDIRLNIGSLANETILSEQQKYGCYLASAHAVGEAQTLRAIEAEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCHHHHHHHHHHHHC
GKLSVEALNAAKAASAIMGMNNVYYRATHLVSNTTYTTMPARLRMNVIGNPGVEKVDFEL
CCEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHH
WSLAVSAINGCGMCLDAHEAELRKHGVTSEQIQAAIRIGAVVNAAARVLAAEAALAAEPA
HHHHHHHHCCCCCEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA