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The map label for this gene is yafV [C]

Identifier: 114799001

GI number: 114799001

Start: 583062

End: 583898

Strand: Direct

Name: yafV [C]

Synonym: HNE_0584

Alternate gene names: 114799001

Gene position: 583062-583898 (Clockwise)

Preceding gene: 114799870

Following gene: 114798783

Centisome position: 15.74

GC content: 66.91

Gene sequence:

>837_bases
ATGAAACTCACCGCCGCCTGTATCCAGATGCGCTCGGGCACCGAGCCTGAAGCAAACCTCGCCGCCGCCACCGCGCTCAT
CCGGCAGGCCGCCGGGCAAGGCGCGCGCTTCATCGCCACGCCCGAGATGACAAACCTGCTGGACATCCGCCCCGGCATGG
CCCGCCCGAAAGTGCGCACAGAGGCGCAGGATGAAAGCCTGCCGGCGTTCCGCGCGCTTGCGTCAGAGCTCGGCATCACG
CTGCTCATCGGCTCCCTGGCGATTGCGCTGGAAGGGGAGGACCGCTTCGCCAATCGCTCCTTCCTTATCGGGCCGGACGG
CGGCGTCCTCGCCCGCTATGACAAGATCCATATGTTCGATGTCGAGGTTGGCGACGGCCAGAACTACCGGGAGTCCCGCG
CTTACCGCCCCGGTGAAACCGCCGTGCTCGCCGCTGCGCCCTTCGGAAAGCTCGGCCTCACCATCTGCTATGATCTCCGC
TTCCCGCATCTCCACCGCGCGCTCGCCAAGGCGGGCGCCGACATCCTCACTATCCCCGCCGCCTTCACGAAGGTCACCGG
CGAGGCTCACTGGCATACGCTGGTGCGCGCCCGCGCCATCGAGACGGGATGTTTCGTGATTGCGCCCGCGCAGGCGGGTA
AACACGAGGACGGGCGCGAGACCTTCGGCCATTCCCTCATCGTCTCGCCCTGGGGCGAGGTGCTGGCCGAAGGCAGCGCG
ACAGAGCCGGGCATCGTGATGGCGGAGATTGACCTCGCAGACGTCGCCAAGGCGCGCAGCCGTATTCCTGCGCTGGGCAA
TGAGCAGACCTTCAGCCTGAAGACGTTTGGCGGTTAG

Upstream 100 bases:

>100_bases
TGCAGGAGGTCTGGTAGAATCTAACAGAATCGGCGCAGCGCCGCCAGCGCCGCCTTTGGGGCGCTGGCCGAATGTGCCTG
CGCGCGCTAGTCTGGCGCCC

Downstream 100 bases:

>100_bases
CCGTTAACGCCCCAGCCGCCGCCGGAACTCGCCATAGCCAAAGTCCGACACCTGCTCCACGCGCCCGTCTTCCCAGCGGA
TGACGAGATTGGCGAGCGGC

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLTAACIQMRSGTEPEANLAAATALIRQAAGQGARFIATPEMTNLLDIRPGMARPKVRTEAQDESLPAFRALASELGIT
LLIGSLAIALEGEDRFANRSFLIGPDGGVLARYDKIHMFDVEVGDGQNYRESRAYRPGETAVLAAAPFGKLGLTICYDLR
FPHLHRALAKAGADILTIPAAFTKVTGEAHWHTLVRARAIETGCFVIAPAQAGKHEDGRETFGHSLIVSPWGEVLAEGSA
TEPGIVMAEIDLADVAKARSRIPALGNEQTFSLKTFGG

Sequences:

>Translated_278_residues
MKLTAACIQMRSGTEPEANLAAATALIRQAAGQGARFIATPEMTNLLDIRPGMARPKVRTEAQDESLPAFRALASELGIT
LLIGSLAIALEGEDRFANRSFLIGPDGGVLARYDKIHMFDVEVGDGQNYRESRAYRPGETAVLAAAPFGKLGLTICYDLR
FPHLHRALAKAGADILTIPAAFTKVTGEAHWHTLVRARAIETGCFVIAPAQAGKHEDGRETFGHSLIVSPWGEVLAEGSA
TEPGIVMAEIDLADVAKARSRIPALGNEQTFSLKTFGG
>Mature_278_residues
MKLTAACIQMRSGTEPEANLAAATALIRQAAGQGARFIATPEMTNLLDIRPGMARPKVRTEAQDESLPAFRALASELGIT
LLIGSLAIALEGEDRFANRSFLIGPDGGVLARYDKIHMFDVEVGDGQNYRESRAYRPGETAVLAAAPFGKLGLTICYDLR
FPHLHRALAKAGADILTIPAAFTKVTGEAHWHTLVRARAIETGCFVIAPAQAGKHEDGRETFGHSLIVSPWGEVLAEGSA
TEPGIVMAEIDLADVAKARSRIPALGNEQTFSLKTFGG

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=280, Percent_Identity=37.8571428571429, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI5031947, Length=280, Percent_Identity=37.8571428571429, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI297632348, Length=280, Percent_Identity=37.8571428571429, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=35.5805243445693, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI297632346, Length=202, Percent_Identity=35.6435643564356, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1786412, Length=212, Percent_Identity=30.188679245283, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=267, Percent_Identity=35.5805243445693, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322335, Length=299, Percent_Identity=32.7759197324415, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323383, Length=272, Percent_Identity=30.5147058823529, Blast_Score=141, Evalue=9e-35,
Organism=Drosophila melanogaster, GI17933642, Length=266, Percent_Identity=39.0977443609023, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI21355835, Length=262, Percent_Identity=29.3893129770992, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29661; Mature: 29661

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTAACIQMRSGTEPEANLAAATALIRQAAGQGARFIATPEMTNLLDIRPGMARPKVRT
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCCCC
EAQDESLPAFRALASELGITLLIGSLAIALEGEDRFANRSFLIGPDGGVLARYDKIHMFD
CCCCCCCHHHHHHHHHCCHHEEEEEEEEEECCCCCCCCCEEEECCCCCEEEEECEEEEEE
VEVGDGQNYRESRAYRPGETAVLAAAPFGKLGLTICYDLRFPHLHRALAKAGADILTIPA
EEECCCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECH
AFTKVTGEAHWHTLVRARAIETGCFVIAPAQAGKHEDGRETFGHSLIVSPWGEVLAEGSA
HHHHHCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHCCEEEECCHHHHHCCCCC
TEPGIVMAEIDLADVAKARSRIPALGNEQTFSLKTFGG
CCCCEEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKLTAACIQMRSGTEPEANLAAATALIRQAAGQGARFIATPEMTNLLDIRPGMARPKVRT
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCCCC
EAQDESLPAFRALASELGITLLIGSLAIALEGEDRFANRSFLIGPDGGVLARYDKIHMFD
CCCCCCCHHHHHHHHHCCHHEEEEEEEEEECCCCCCCCCEEEECCCCCEEEEECEEEEEE
VEVGDGQNYRESRAYRPGETAVLAAAPFGKLGLTICYDLRFPHLHRALAKAGADILTIPA
EEECCCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECH
AFTKVTGEAHWHTLVRARAIETGCFVIAPAQAGKHEDGRETFGHSLIVSPWGEVLAEGSA
HHHHHCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHCCEEEECCHHHHHCCCCC
TEPGIVMAEIDLADVAKARSRIPALGNEQTFSLKTFGG
CCCCEEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]