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The map label for this gene is fiu [H]

Identifier: 114798931

GI number: 114798931

Start: 2196948

End: 2199380

Strand: Direct

Name: fiu [H]

Synonym: HNE_2116

Alternate gene names: 114798931

Gene position: 2196948-2199380 (Clockwise)

Preceding gene: 114797055

Following gene: 114798632

Centisome position: 59.3

GC content: 60.05

Gene sequence:

>2433_bases
ATGGCCGTTCTTGGAGGGTTCTGCCCATTTCCGCCTGTGGCCGGCCCGGCCGCATGGGAGTTTGGACCTTCCTGGCACGT
TCATGGCCAGACACCCCGCCTTGCGGGTTTCCTGACAGCCAAGCCGTCCGCGAGAAGCGCATGCACCTGCGCCGCCCGGA
CATTTCCCATTCTGGAGACGATAATGATACGCAGTCGCAAACATGGACTGAAAACTAGCCTTGCCCTTATCGCCGCAATG
AGCGGCACCCTACATGCCCATGCCGAGGCGGATGATGCCCGCCGGAGTGATCCCGAGAAGCGGGAAGAAACGGTGATTGT
CGAAGGCGAGAGCCTCTACATCGTGCCTCATGTTTCGTCGCCAAAACTGACGCAAGAGCTGGTGAACACGCCGCAGACGA
TCAGCGTGATCTCCGGCCAGCTGATTGCCGACCAGGGCGCGGTCAGCCTGATGGAAGCGCTGCGCAATACGCCGGGCATC
ACGATGCAGCTGGGCGAGAACGGCAACACCTCCTCAGGGGATACGTTCACGATGCGGGGCTTCTCCTCGCAAAGCTCGAT
CTTCCAGGACGGTATTCGTGACCTGGGCGCGGTGACCCGTGACAGCTTTAACCTCGAGCAGATCGAGGTGGCCAAGGGGC
CGGCCGGCTCCGACATCGGCCGGGGAGCATCCTCGGGCTATATCAACCAGGTTTCCAAGACACCGCTGGATGACGACTTT
ACGTCACTGTTTGCGGGCGCGACCAGCGAAGGCGGCGTGCGCCTGACGGGGGACGCCAACAAGATGTTGACCGGCACGGC
CGGGGTTCGCCTCAATGTGATGGTTCAGGACATGCCGGTTCCCGGCCGCGATGAAGTGACCAATAAGGGTTACGGCATTG
CGCCCTCCATCGCGTTCGGCGTTGGGACGGGTACGGAGTTCCAGCTGTTCGCCCAGCACATCATTCAGGAAAATGTACCT
GATGGCGGCATTCCCTCTATCGGTCTTGAGGGTTTCTACAATGCCGATGAAACGCTTCTGGCCGGCGCGGCTGTAGACCG
GTCGAACTTCTATGGCAGCAAGTCTGACTTCGAGGACGTGGAAGCCAACATGATCACCGCAAAGATGATCCATGATCTTG
GCGGCGGCCTGACCCTGACCAGCACTGCACGTTACGGCAAGACGCAGATGGACCGCGTGCTGACCGGCATCAATGGCCTG
GACGCGCCCTCCTCCGATCCCTCGACCTGGACGGTTTCCCGTTCGCGTCAACGCGTGGACCAGACCAATGACATTCTGGG
CAATCAGACGATCATCACGGGCAGCTTCAACACCGGCCGCCTGGTGCACGATTTCTCGACGGGGATTGAGGCGCTGAACG
AATCCCAGAAATCGGGTTCGTTTTCCACAACCGGCCTGACGACTCCGGCCGCCTCGCTCTACAATCCTGATCCGAACATT
GTTCTGCCCACCCCCTACCCTTCGGGCGGCAAGGCAGATGGCAGCACGACGACGCTTGCCGCCTTCCTTTTTGATACGAT
CAATCTGGACGAAAAATGGTATTTCACCGCCGGCATTCGCGCGGAGAATTACGAGACGGATGTGAACGGTGTGACGATCA
CCTCTTCACGTTCGCACCCTGATCTTCCTCCCGGCACGGCGCTTGCCTACGATCTGTCTGATGATGGCAACCTCGTCAGC
TGGAAACTCGCAGGTCTCTACAAGCCGCGGGAGAATGGCAGCGTCTATATCAGCTATGGCAACTCGCTGACCCCGCCGGG
CGGGGCAAACTTCTCGCTGTCGTCTGGCGAGTCCAGCATCAACAATCCCGCCTTCGATCCGCAGGAAACGCAGAACCTGG
AAGTGGGCACGAAATGGGACCTGTTCGGCGAGCATCTGGCGCTGGCGGCGGCCTATTACTCCACCACCAACAAGGACGAG
CTTTCCGTGCTTGATCCGGACACCAACACTTATGAACAGCTGGGCGAGCGCAAGGTGGAAGGTGTTGAGCTTTCGGCCGT
TGGCAAGATTACGCCGGACTGGCAGGTTTCCGCCAGCCTGACGACCATCGATACCGAAGTCACTGAAGGGACCACGGGCA
ACAACTCGGAAGGCGCTTCGTCGCGCTGGTCGCCCGACCTCGCCGCGACGGTCTGGACGACCTATAATCTGACGCCGGCC
TTCACCTTTGGCGGCGGCGCGCGGTATATGGGCGAGCAGAAACGGGTGGTGAACCCCGGCACCGACATCTCCACACAGAA
TGTTCCGGTTATCCCGGAAGCCTGGGTGGTGGACGCGATGGCGCGGTATCAGTTCACCGAGCGGCTGGCGCTTCAGCTGA
ACGTGTATAACCTCTTTGACGAGGATTACATTTCGACGCTGAACAATTCCGGTGCACGCCTGACACCGGGCCAACCGACA
TCTGCGTATCTTTCGCTGAACGTCCGGTTCTAG

Upstream 100 bases:

>100_bases
GCTGCTCCGGGTCTTCCGGCGTTGGTGAGTCCTGTGCATCGGGCATGGGCCAGCGCCGCCAGCCACCCATTGGAGAGGAG
AGGTAATCCATCCCGGCCCG

Downstream 100 bases:

>100_bases
AGACGAGGAAAACGGCCATGCTCCTGCACATTCCGGAAGTCCTGAACGGGCAGGAGCTGGCCACGCTCCGCGAAACACTT
GCTGGCGCAGACTGGCAAGA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Ferric iron uptake protein; TonB-dependent receptor fiu [H]

Number of amino acids: Translated: 810; Mature: 809

Protein sequence:

>810_residues
MAVLGGFCPFPPVAGPAAWEFGPSWHVHGQTPRLAGFLTAKPSARSACTCAARTFPILETIMIRSRKHGLKTSLALIAAM
SGTLHAHAEADDARRSDPEKREETVIVEGESLYIVPHVSSPKLTQELVNTPQTISVISGQLIADQGAVSLMEALRNTPGI
TMQLGENGNTSSGDTFTMRGFSSQSSIFQDGIRDLGAVTRDSFNLEQIEVAKGPAGSDIGRGASSGYINQVSKTPLDDDF
TSLFAGATSEGGVRLTGDANKMLTGTAGVRLNVMVQDMPVPGRDEVTNKGYGIAPSIAFGVGTGTEFQLFAQHIIQENVP
DGGIPSIGLEGFYNADETLLAGAAVDRSNFYGSKSDFEDVEANMITAKMIHDLGGGLTLTSTARYGKTQMDRVLTGINGL
DAPSSDPSTWTVSRSRQRVDQTNDILGNQTIITGSFNTGRLVHDFSTGIEALNESQKSGSFSTTGLTTPAASLYNPDPNI
VLPTPYPSGGKADGSTTTLAAFLFDTINLDEKWYFTAGIRAENYETDVNGVTITSSRSHPDLPPGTALAYDLSDDGNLVS
WKLAGLYKPRENGSVYISYGNSLTPPGGANFSLSSGESSINNPAFDPQETQNLEVGTKWDLFGEHLALAAAYYSTTNKDE
LSVLDPDTNTYEQLGERKVEGVELSAVGKITPDWQVSASLTTIDTEVTEGTTGNNSEGASSRWSPDLAATVWTTYNLTPA
FTFGGGARYMGEQKRVVNPGTDISTQNVPVIPEAWVVDAMARYQFTERLALQLNVYNLFDEDYISTLNNSGARLTPGQPT
SAYLSLNVRF

Sequences:

>Translated_810_residues
MAVLGGFCPFPPVAGPAAWEFGPSWHVHGQTPRLAGFLTAKPSARSACTCAARTFPILETIMIRSRKHGLKTSLALIAAM
SGTLHAHAEADDARRSDPEKREETVIVEGESLYIVPHVSSPKLTQELVNTPQTISVISGQLIADQGAVSLMEALRNTPGI
TMQLGENGNTSSGDTFTMRGFSSQSSIFQDGIRDLGAVTRDSFNLEQIEVAKGPAGSDIGRGASSGYINQVSKTPLDDDF
TSLFAGATSEGGVRLTGDANKMLTGTAGVRLNVMVQDMPVPGRDEVTNKGYGIAPSIAFGVGTGTEFQLFAQHIIQENVP
DGGIPSIGLEGFYNADETLLAGAAVDRSNFYGSKSDFEDVEANMITAKMIHDLGGGLTLTSTARYGKTQMDRVLTGINGL
DAPSSDPSTWTVSRSRQRVDQTNDILGNQTIITGSFNTGRLVHDFSTGIEALNESQKSGSFSTTGLTTPAASLYNPDPNI
VLPTPYPSGGKADGSTTTLAAFLFDTINLDEKWYFTAGIRAENYETDVNGVTITSSRSHPDLPPGTALAYDLSDDGNLVS
WKLAGLYKPRENGSVYISYGNSLTPPGGANFSLSSGESSINNPAFDPQETQNLEVGTKWDLFGEHLALAAAYYSTTNKDE
LSVLDPDTNTYEQLGERKVEGVELSAVGKITPDWQVSASLTTIDTEVTEGTTGNNSEGASSRWSPDLAATVWTTYNLTPA
FTFGGGARYMGEQKRVVNPGTDISTQNVPVIPEAWVVDAMARYQFTERLALQLNVYNLFDEDYISTLNNSGARLTPGQPT
SAYLSLNVRF
>Mature_809_residues
AVLGGFCPFPPVAGPAAWEFGPSWHVHGQTPRLAGFLTAKPSARSACTCAARTFPILETIMIRSRKHGLKTSLALIAAMS
GTLHAHAEADDARRSDPEKREETVIVEGESLYIVPHVSSPKLTQELVNTPQTISVISGQLIADQGAVSLMEALRNTPGIT
MQLGENGNTSSGDTFTMRGFSSQSSIFQDGIRDLGAVTRDSFNLEQIEVAKGPAGSDIGRGASSGYINQVSKTPLDDDFT
SLFAGATSEGGVRLTGDANKMLTGTAGVRLNVMVQDMPVPGRDEVTNKGYGIAPSIAFGVGTGTEFQLFAQHIIQENVPD
GGIPSIGLEGFYNADETLLAGAAVDRSNFYGSKSDFEDVEANMITAKMIHDLGGGLTLTSTARYGKTQMDRVLTGINGLD
APSSDPSTWTVSRSRQRVDQTNDILGNQTIITGSFNTGRLVHDFSTGIEALNESQKSGSFSTTGLTTPAASLYNPDPNIV
LPTPYPSGGKADGSTTTLAAFLFDTINLDEKWYFTAGIRAENYETDVNGVTITSSRSHPDLPPGTALAYDLSDDGNLVSW
KLAGLYKPRENGSVYISYGNSLTPPGGANFSLSSGESSINNPAFDPQETQNLEVGTKWDLFGEHLALAAAYYSTTNKDEL
SVLDPDTNTYEQLGERKVEGVELSAVGKITPDWQVSASLTTIDTEVTEGTTGNNSEGASSRWSPDLAATVWTTYNLTPAF
TFGGGARYMGEQKRVVNPGTDISTQNVPVIPEAWVVDAMARYQFTERLALQLNVYNLFDEDYISTLNNSGARLTPGQPTS
AYLSLNVRF

Specific function: Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein

COG id: COG4774

COG function: function code P; Outer membrane receptor for monomeric catechols

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=728, Percent_Identity=39.1483516483516, Blast_Score=484, Evalue=1e-137,
Organism=Escherichia coli, GI1786344, Length=787, Percent_Identity=22.2363405336722, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1787344, Length=753, Percent_Identity=23.7715803452855, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86431; Mature: 86299

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLGGFCPFPPVAGPAAWEFGPSWHVHGQTPRLAGFLTAKPSARSACTCAARTFPILET
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
IMIRSRKHGLKTSLALIAAMSGTLHAHAEADDARRSDPEKREETVIVEGESLYIVPHVSS
HHHHHHHCCHHHHHHHHHHHCCCEEECCCCCHHHCCCCCHHCCEEEEECCEEEEEECCCC
PKLTQELVNTPQTISVISGQLIADQGAVSLMEALRNTPGITMQLGENGNTSSGDTFTMRG
CHHHHHHHCCCCEEEHHCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEC
FSSQSSIFQDGIRDLGAVTRDSFNLEQIEVAKGPAGSDIGRGASSGYINQVSKTPLDDDF
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCHHH
TSLFAGATSEGGVRLTGDANKMLTGTAGVRLNVMVQDMPVPGRDEVTNKGYGIAPSIAFG
HHHHCCCCCCCCEEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VGTGTEFQLFAQHIIQENVPDGGIPSIGLEGFYNADETLLAGAAVDRSNFYGSKSDFEDV
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
EANMITAKMIHDLGGGLTLTSTARYGKTQMDRVLTGINGLDAPSSDPSTWTVSRSRQRVD
HHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHH
QTNDILGNQTIITGSFNTGRLVHDFSTGIEALNESQKSGSFSTTGLTTPAASLYNPDPNI
HHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHCCCCCCE
VLPTPYPSGGKADGSTTTLAAFLFDTINLDEKWYFTAGIRAENYETDVNGVTITSSRSHP
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCC
DLPPGTALAYDLSDDGNLVSWKLAGLYKPRENGSVYISYGNSLTPPGGANFSLSSGESSI
CCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCCCCC
NNPAFDPQETQNLEVGTKWDLFGEHLALAAAYYSTTNKDELSVLDPDTNTYEQLGERKVE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCC
GVELSAVGKITPDWQVSASLTTIDTEVTEGTTGNNSEGASSRWSPDLAATVWTTYNLTPA
CEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEE
FTFGGGARYMGEQKRVVNPGTDISTQNVPVIPEAWVVDAMARYQFTERLALQLNVYNLFD
EEECCCHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEHHHCC
EDYISTLNNSGARLTPGQPTSAYLSLNVRF
HHHHHHHCCCCCEECCCCCCEEEEEEEEEC
>Mature Secondary Structure 
AVLGGFCPFPPVAGPAAWEFGPSWHVHGQTPRLAGFLTAKPSARSACTCAARTFPILET
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
IMIRSRKHGLKTSLALIAAMSGTLHAHAEADDARRSDPEKREETVIVEGESLYIVPHVSS
HHHHHHHCCHHHHHHHHHHHCCCEEECCCCCHHHCCCCCHHCCEEEEECCEEEEEECCCC
PKLTQELVNTPQTISVISGQLIADQGAVSLMEALRNTPGITMQLGENGNTSSGDTFTMRG
CHHHHHHHCCCCEEEHHCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEC
FSSQSSIFQDGIRDLGAVTRDSFNLEQIEVAKGPAGSDIGRGASSGYINQVSKTPLDDDF
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCHHH
TSLFAGATSEGGVRLTGDANKMLTGTAGVRLNVMVQDMPVPGRDEVTNKGYGIAPSIAFG
HHHHCCCCCCCCEEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VGTGTEFQLFAQHIIQENVPDGGIPSIGLEGFYNADETLLAGAAVDRSNFYGSKSDFEDV
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
EANMITAKMIHDLGGGLTLTSTARYGKTQMDRVLTGINGLDAPSSDPSTWTVSRSRQRVD
HHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHH
QTNDILGNQTIITGSFNTGRLVHDFSTGIEALNESQKSGSFSTTGLTTPAASLYNPDPNI
HHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHCCCCCCE
VLPTPYPSGGKADGSTTTLAAFLFDTINLDEKWYFTAGIRAENYETDVNGVTITSSRSHP
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCC
DLPPGTALAYDLSDDGNLVSWKLAGLYKPRENGSVYISYGNSLTPPGGANFSLSSGESSI
CCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCCCCC
NNPAFDPQETQNLEVGTKWDLFGEHLALAAAYYSTTNKDELSVLDPDTNTYEQLGERKVE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCC
GVELSAVGKITPDWQVSASLTTIDTEVTEGTTGNNSEGASSRWSPDLAATVWTTYNLTPA
CEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEE
FTFGGGARYMGEQKRVVNPGTDISTQNVPVIPEAWVVDAMARYQFTERLALQLNVYNLFD
EEECCCHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEHHHCC
EDYISTLNNSGARLTPGQPTSAYLSLNVRF
HHHHHHHCCCCCEECCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]