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The map label for this gene is lysK [H]

Identifier: 114798391

GI number: 114798391

Start: 3248802

End: 3250394

Strand: Reverse

Name: lysK [H]

Synonym: HNE_3072

Alternate gene names: 114798391

Gene position: 3250394-3248802 (Counterclockwise)

Preceding gene: 114798498

Following gene: 114797671

Centisome position: 87.73

GC content: 61.83

Gene sequence:

>1593_bases
ATGACCGACCTTTCAACACTCGCCCAATCTGCCAAAGCCTGGCCTTTCGAGCTTGCCCGCGCGCTGGAAAAGCGTGTCGC
CGAGCAGGTGAAGGCCGGTGAGCGCAAGGCGGATGATCCGGTCATCTTTGAGACAGGCTACGGCCCCTCGGGCCTGCCGC
ATATCGGCACCTTCGGCGAAGTTGTCCGCACCACTATGGTGCGCCACGCTTTTGAAGTACTCACGGCGGGCAAATACGCC
ACGCGCCTCATCTGCGTGTCTGACGATATGGACGGCATGCGGAAGGTTCCCGAAACGGTGCCGGACCCCCGATCGCTGGA
GCAGTTCCTCCAGAAGCCGCTGACGACCGTGCCCGACCCGTTTGGCACACATGCCTCCTACGGCGCGCACATGAATGCGC
GCCTCTGCGCATTTCTCGACAAGTTCGGCTTCCAGTACGAGTTTCTCTCGGCGACCGACTGTTACCGGTCTGGGCGGTTT
GACGCGATGTTGCTGCGCGCGGCGGAGAAGTATCAGGCGATCATGGATGTGATGCTGCCCTCCCTTGGCGAGGAGCGCCG
CGCGACCTATTCGCCCTTCCTGCCGATCAGCCCGAGCACCGGCCGGGTGCTGTATGTGCCGATGAAGAAGGTGGATGCGG
CCCGCGGTGAAGTGACGTTCACGGATGAAGATGGCACCGATGTGACGCTTCCCGTAACGGGCGGGGCGGTGAAGATGCAG
TGGAAGCCGGATTTCGGCATGCGCTGGGCGGCCCTTGGCGTGGACTTTGAAATGTTCGGCAAGGATCACCAGGCCAACGC
GCCGATCTATTCGAAGATCTGCCGCATCCTCGGCGCCCGCCCGCCGGAACAATATGTCTATGAGCTATTCCTGGACGAGA
AGGGCGAGAAGATCTCCAAGACCAAGGGCAATGGCATCTCGGTGGAGCAGTGGCTGACCTATGCGCCGGACGAAAGCCTT
GCGCTCTTCCAGTTCCAGAAGCCGCGCGTCGCCAAGAAGCTGTATTTCGACGTGATCCCGAAGGCGGTCGACGAATACCT
GACCTTCCTTGAGAAGTTCCCGCAGGAAGAGGCCGCCGCCCAGCTGGAAAATCCCGTCTGGCATATTCATTCGGGCCGCC
CGCCCCAATGGTCGAGCCCGGTCAGCTTTGCGCTGCTGATGAACCTCGTTGCCGTGGCCAACCCCACCGATACGTCCCAG
CTCTGGGCCTATATCATGCGGTATGCTCCGGAAGCGTCGCCCGAAACCCATCCGCTGCTTGATGAGCTCGCCGGCTATGC
CATGCGCTATTACCGCGATTTCGTGCTGCCTGCGAAAACCTTCCGGGCGCCCACCGATCAGGAGCGCGCCGCAATGGCCG
ATCTCTCGGCCCGGTTCAAGGTATTCTCCGATGAGCCCACCGGCGAGAACTTGCAGACGCTGACCTTCAGCGTCGGCAAG
GATCATGGCTTCGAGAACCTGCGCGAATGGTTCAAGGCGCTTTATGAAGTGCTTCTGGGACAGGAGCAGGGGCCGCGCTT
TGGCAGCTTTGCGGCGCTCTATGGCGTGGCCGAAACCGCCACGCTGATCGACGACGCGCTGGCACGTGGCTGA

Upstream 100 bases:

>100_bases
TGTCAAAGATTTTTTACGGATCGAGACGGGCTTTGCTTGACGCCTTCCGGCAGCGCATCTAGGTCCGGCCCATCAATCTC
TCATCTGTGATCGACGTTCC

Downstream 100 bases:

>100_bases
GTGGTAATCTGAAAGTAACGCAAATCCGGGTTATAGGTGGTCCTTCTCAAGGAGCCCTCGCCCATGCGTTCACTCATTCT
CGCCACGCTCGCCCTGACGC

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTDLSTLAQSAKAWPFELARALEKRVAEQVKAGERKADDPVIFETGYGPSGLPHIGTFGEVVRTTMVRHAFEVLTAGKYA
TRLICVSDDMDGMRKVPETVPDPRSLEQFLQKPLTTVPDPFGTHASYGAHMNARLCAFLDKFGFQYEFLSATDCYRSGRF
DAMLLRAAEKYQAIMDVMLPSLGEERRATYSPFLPISPSTGRVLYVPMKKVDAARGEVTFTDEDGTDVTLPVTGGAVKMQ
WKPDFGMRWAALGVDFEMFGKDHQANAPIYSKICRILGARPPEQYVYELFLDEKGEKISKTKGNGISVEQWLTYAPDESL
ALFQFQKPRVAKKLYFDVIPKAVDEYLTFLEKFPQEEAAAQLENPVWHIHSGRPPQWSSPVSFALLMNLVAVANPTDTSQ
LWAYIMRYAPEASPETHPLLDELAGYAMRYYRDFVLPAKTFRAPTDQERAAMADLSARFKVFSDEPTGENLQTLTFSVGK
DHGFENLREWFKALYEVLLGQEQGPRFGSFAALYGVAETATLIDDALARG

Sequences:

>Translated_530_residues
MTDLSTLAQSAKAWPFELARALEKRVAEQVKAGERKADDPVIFETGYGPSGLPHIGTFGEVVRTTMVRHAFEVLTAGKYA
TRLICVSDDMDGMRKVPETVPDPRSLEQFLQKPLTTVPDPFGTHASYGAHMNARLCAFLDKFGFQYEFLSATDCYRSGRF
DAMLLRAAEKYQAIMDVMLPSLGEERRATYSPFLPISPSTGRVLYVPMKKVDAARGEVTFTDEDGTDVTLPVTGGAVKMQ
WKPDFGMRWAALGVDFEMFGKDHQANAPIYSKICRILGARPPEQYVYELFLDEKGEKISKTKGNGISVEQWLTYAPDESL
ALFQFQKPRVAKKLYFDVIPKAVDEYLTFLEKFPQEEAAAQLENPVWHIHSGRPPQWSSPVSFALLMNLVAVANPTDTSQ
LWAYIMRYAPEASPETHPLLDELAGYAMRYYRDFVLPAKTFRAPTDQERAAMADLSARFKVFSDEPTGENLQTLTFSVGK
DHGFENLREWFKALYEVLLGQEQGPRFGSFAALYGVAETATLIDDALARG
>Mature_529_residues
TDLSTLAQSAKAWPFELARALEKRVAEQVKAGERKADDPVIFETGYGPSGLPHIGTFGEVVRTTMVRHAFEVLTAGKYAT
RLICVSDDMDGMRKVPETVPDPRSLEQFLQKPLTTVPDPFGTHASYGAHMNARLCAFLDKFGFQYEFLSATDCYRSGRFD
AMLLRAAEKYQAIMDVMLPSLGEERRATYSPFLPISPSTGRVLYVPMKKVDAARGEVTFTDEDGTDVTLPVTGGAVKMQW
KPDFGMRWAALGVDFEMFGKDHQANAPIYSKICRILGARPPEQYVYELFLDEKGEKISKTKGNGISVEQWLTYAPDESLA
LFQFQKPRVAKKLYFDVIPKAVDEYLTFLEKFPQEEAAAQLENPVWHIHSGRPPQWSSPVSFALLMNLVAVANPTDTSQL
WAYIMRYAPEASPETHPLLDELAGYAMRYYRDFVLPAKTFRAPTDQERAAMADLSARFKVFSDEPTGENLQTLTFSVGKD
HGFENLREWFKALYEVLLGQEQGPRFGSFAALYGVAETATLIDDALARG

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 59374; Mature: 59243

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSTLAQSAKAWPFELARALEKRVAEQVKAGERKADDPVIFETGYGPSGLPHIGTFGE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHH
VVRTTMVRHAFEVLTAGKYATRLICVSDDMDGMRKVPETVPDPRSLEQFLQKPLTTVPDP
HHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHCCHHCCCCC
FGTHASYGAHMNARLCAFLDKFGFQYEFLSATDCYRSGRFDAMLLRAAEKYQAIMDVMLP
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLGEERRATYSPFLPISPSTGRVLYVPMKKVDAARGEVTFTDEDGTDVTLPVTGGAVKMQ
CCCCHHHCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEE
WKPDFGMRWAALGVDFEMFGKDHQANAPIYSKICRILGARPPEQYVYELFLDEKGEKISK
ECCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
TKGNGISVEQWLTYAPDESLALFQFQKPRVAKKLYFDVIPKAVDEYLTFLEKFPQEEAAA
CCCCCCCHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLENPVWHIHSGRPPQWSSPVSFALLMNLVAVANPTDTSQLWAYIMRYAPEASPETHPLL
HHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHH
DELAGYAMRYYRDFVLPAKTFRAPTDQERAAMADLSARFKVFSDEPTGENLQTLTFSVGK
HHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCEEEEEECCC
DHGFENLREWFKALYEVLLGQEQGPRFGSFAALYGVAETATLIDDALARG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDLSTLAQSAKAWPFELARALEKRVAEQVKAGERKADDPVIFETGYGPSGLPHIGTFGE
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHH
VVRTTMVRHAFEVLTAGKYATRLICVSDDMDGMRKVPETVPDPRSLEQFLQKPLTTVPDP
HHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHCCHHCCCCC
FGTHASYGAHMNARLCAFLDKFGFQYEFLSATDCYRSGRFDAMLLRAAEKYQAIMDVMLP
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLGEERRATYSPFLPISPSTGRVLYVPMKKVDAARGEVTFTDEDGTDVTLPVTGGAVKMQ
CCCCHHHCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEE
WKPDFGMRWAALGVDFEMFGKDHQANAPIYSKICRILGARPPEQYVYELFLDEKGEKISK
ECCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
TKGNGISVEQWLTYAPDESLALFQFQKPRVAKKLYFDVIPKAVDEYLTFLEKFPQEEAAA
CCCCCCCHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLENPVWHIHSGRPPQWSSPVSFALLMNLVAVANPTDTSQLWAYIMRYAPEASPETHPLL
HHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHH
DELAGYAMRYYRDFVLPAKTFRAPTDQERAAMADLSARFKVFSDEPTGENLQTLTFSVGK
HHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCEEEEEECCC
DHGFENLREWFKALYEVLLGQEQGPRFGSFAALYGVAETATLIDDALARG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]