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The map label for this gene is yfmJ [H]

Identifier: 114798224

GI number: 114798224

Start: 1096086

End: 1097099

Strand: Reverse

Name: yfmJ [H]

Synonym: HNE_1087

Alternate gene names: 114798224

Gene position: 1097099-1096086 (Counterclockwise)

Preceding gene: 114799996

Following gene: 114800382

Centisome position: 29.61

GC content: 63.02

Gene sequence:

>1014_bases
ATGAAACTCTACACCCTGAAAACTGAGATCGACGCTGTTCCGGTTGCGGATGATTTTATCGCCATTGAGGCGCCGCGCCC
GGACTGCCCGGACGGCGGCATTGTCGCGCGGGTGATCTATCTCTCGCTTGACCCCTATGTCGGCTCCCGCCTGCGCGGGC
GGCATATGGGCGAAGCCCCGCCCAAGCCCATGGAAGGCGCCATTCCCGGCGCCATCGTCGGCCAGGTCGTAAAGAGCCGC
GCCGCAGGCGTGTCCGAAGGCGACTTTGTTCACGCCATGGAAGGCGGCTGGCAGGAATTTGCCGCCATTCCCGCGGGCCA
TTTCCGCAAACTTGACCCCAAATCTGCCCCGCTGCGCGCTCATATCGGCGTGCTCGGCATGCCCGGCCTCACGGCTTGGG
CAGGCATTACCCAGCTGGCGAAAGTCATGGCCGGGGACGTTGTTCTCATCGACGCTGCCGCTGGCGCCGTAGGCGGAACA
GCTGGCCAGATCGCCCGCATCAAAGGCGCTTCAAAGGCTGTCGGCATTGCTGGCGGCCCGGAGAAATGCCGCCTGGTGAC
AGAGACTTACGGCTTTGATGCCTGCATCGACTATAAGGCAGAAGGTTGGCAGGCCGCGCTGAAAGAAGCGCTCCCCGAAG
GCGCCAGCGTGTTCTTCGAGAATGTCTCCGCCGAGATGGCGATGACGGCTCTCTCCGTTTCGCAGACTTATGTGCGCGGC
GTGCTCTGCGGGCTGGCAGATGCCTACCAGTCATCCGGCCCTGCCCCTCACGCCCTCAATGCCGGCGCCATCATTGGCAA
GCGCGCCCAGCTGCGTGGCCTGGTCGTCTACGACTTCTATTCCCGCTGGGACGAATATGCCGCCGAAGCCGCCGCCTGGA
TTCGCGATGGCAAGCTCGCCTTCGCCGAAGATCATGCAGATGGCCTCGACCAGGCACCCGCCCTCTTCGCCAAACTCATG
CGCGGCGCAAATGTCGGCAAACCCATTATTACAGTTTCAGAGGAGCAGGCATAA

Upstream 100 bases:

>100_bases
GGATCACACCGCCCACCCGCCGCGAAGGCCCCATATACAAAGGCAAACGCGCCGGAACGATCAAGGATCTTGACGGCGCC
CTGATCGAGATTGTCGAAGC

Downstream 100 bases:

>100_bases
TGGCCCGCGTGAAGAGATCATACGTCGACGGAACATACGGCCAGTTGCATTACCGCATCGCGCAGCCGGAAAAGCCCTCG
TCCCTCCCCCCGCTATACTG

Product: L4BD family NADP-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKLYTLKTEIDAVPVADDFIAIEAPRPDCPDGGIVARVIYLSLDPYVGSRLRGRHMGEAPPKPMEGAIPGAIVGQVVKSR
AAGVSEGDFVHAMEGGWQEFAAIPAGHFRKLDPKSAPLRAHIGVLGMPGLTAWAGITQLAKVMAGDVVLIDAAAGAVGGT
AGQIARIKGASKAVGIAGGPEKCRLVTETYGFDACIDYKAEGWQAALKEALPEGASVFFENVSAEMAMTALSVSQTYVRG
VLCGLADAYQSSGPAPHALNAGAIIGKRAQLRGLVVYDFYSRWDEYAAEAAAWIRDGKLAFAEDHADGLDQAPALFAKLM
RGANVGKPIITVSEEQA

Sequences:

>Translated_337_residues
MKLYTLKTEIDAVPVADDFIAIEAPRPDCPDGGIVARVIYLSLDPYVGSRLRGRHMGEAPPKPMEGAIPGAIVGQVVKSR
AAGVSEGDFVHAMEGGWQEFAAIPAGHFRKLDPKSAPLRAHIGVLGMPGLTAWAGITQLAKVMAGDVVLIDAAAGAVGGT
AGQIARIKGASKAVGIAGGPEKCRLVTETYGFDACIDYKAEGWQAALKEALPEGASVFFENVSAEMAMTALSVSQTYVRG
VLCGLADAYQSSGPAPHALNAGAIIGKRAQLRGLVVYDFYSRWDEYAAEAAAWIRDGKLAFAEDHADGLDQAPALFAKLM
RGANVGKPIITVSEEQA
>Mature_337_residues
MKLYTLKTEIDAVPVADDFIAIEAPRPDCPDGGIVARVIYLSLDPYVGSRLRGRHMGEAPPKPMEGAIPGAIVGQVVKSR
AAGVSEGDFVHAMEGGWQEFAAIPAGHFRKLDPKSAPLRAHIGVLGMPGLTAWAGITQLAKVMAGDVVLIDAAAGAVGGT
AGQIARIKGASKAVGIAGGPEKCRLVTETYGFDACIDYKAEGWQAALKEALPEGASVFFENVSAEMAMTALSVSQTYVRG
VLCGLADAYQSSGPAPHALNAGAIIGKRAQLRGLVVYDFYSRWDEYAAEAAAWIRDGKLAFAEDHADGLDQAPALFAKLM
RGANVGKPIITVSEEQA

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=331, Percent_Identity=32.6283987915408, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI226246680, Length=331, Percent_Identity=32.6283987915408, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI22748929, Length=331, Percent_Identity=32.6283987915408, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=31.3609467455621, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=31.3609467455621, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226056130, Length=312, Percent_Identity=31.0897435897436, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI28557745, Length=325, Percent_Identity=24.9230769230769, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI226510941, Length=340, Percent_Identity=33.5294117647059, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI133901712, Length=334, Percent_Identity=29.3413173652695, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI133901710, Length=334, Percent_Identity=29.3413173652695, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323504, Length=343, Percent_Identity=29.1545189504373, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35262; Mature: 35262

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYTLKTEIDAVPVADDFIAIEAPRPDCPDGGIVARVIYLSLDPYVGSRLRGRHMGEAP
CEEEEEECCCCEECCCCCEEEEECCCCCCCCCCCEEEEEEEEECCHHCCHHCCCCCCCCC
PKPMEGAIPGAIVGQVVKSRAAGVSEGDFVHAMEGGWQEFAAIPAGHFRKLDPKSAPLRA
CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCCCCCCCCCCCCCCEE
HIGVLGMPGLTAWAGITQLAKVMAGDVVLIDAAAGAVGGTAGQIARIKGASKAVGIAGGP
ECCEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCH
EKCRLVTETYGFDACIDYKAEGWQAALKEALPEGASVFFENVSAEMAMTALSVSQTYVRG
HHEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLCGLADAYQSSGPAPHALNAGAIIGKRAQLRGLVVYDFYSRWDEYAAEAAAWIRDGKLA
HHHHHHHHHHCCCCCCCCCCCCCEECCHHHHCEEEEEHHHHHHHHHHHHHHHHHHCCCEE
FAEDHADGLDQAPALFAKLMRGANVGKPIITVSEEQA
EECCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
>Mature Secondary Structure
MKLYTLKTEIDAVPVADDFIAIEAPRPDCPDGGIVARVIYLSLDPYVGSRLRGRHMGEAP
CEEEEEECCCCEECCCCCEEEEECCCCCCCCCCCEEEEEEEEECCHHCCHHCCCCCCCCC
PKPMEGAIPGAIVGQVVKSRAAGVSEGDFVHAMEGGWQEFAAIPAGHFRKLDPKSAPLRA
CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCCCCCCCCCCCCCCEE
HIGVLGMPGLTAWAGITQLAKVMAGDVVLIDAAAGAVGGTAGQIARIKGASKAVGIAGGP
ECCEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCH
EKCRLVTETYGFDACIDYKAEGWQAALKEALPEGASVFFENVSAEMAMTALSVSQTYVRG
HHEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLCGLADAYQSSGPAPHALNAGAIIGKRAQLRGLVVYDFYSRWDEYAAEAAAWIRDGKLA
HHHHHHHHHHCCCCCCCCCCCCCEECCHHHHCEEEEEHHHHHHHHHHHHHHHHHHCCCEE
FAEDHADGLDQAPALFAKLMRGANVGKPIITVSEEQA
EECCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]