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The map label for this gene is erg3 [H]

Identifier: 114798176

GI number: 114798176

Start: 2254361

End: 2255350

Strand: Direct

Name: erg3 [H]

Synonym: HNE_2168

Alternate gene names: 114798176

Gene position: 2254361-2255350 (Clockwise)

Preceding gene: 114797205

Following gene: 114798724

Centisome position: 60.85

GC content: 60.51

Gene sequence:

>990_bases
ATGGAGTTCACGCCCTTTCCCGATGTCACCGCGCTGGCGGCCCCCGTCTTCGTGGCGTCGGTTGCATGGGAATGGTGGGC
AGTGAAAACCGGACGGGCCAAGGGCCGCTATGAGACGAAGGACGCCCTGGCGTCGATGTCGATGGGGCTGGGCAATGTTG
TCGTCAATACGCTGACGGGCACGATTGCGCTCTGGATGATGATGCTGGCCTGGCCCTACCGGGTGGCGACCATTCCGTTT
GCCTGGTGGAGCTTTGCGCTCTGCTTCGTGGTGTACGATCTGATCTATTACTGGAAGCACCGCTTCGCCCATCGGATGCG
CTGGTTCTGGATGGAGCACGTTACCCACCACTCCTCGCAGCACTACAATCTGACGACTGCCCTGCGCCAGCCCTGGTTTG
GGCCGTTTACGGGGCTGATCCTGGTGGGGCTGCCGCTCGTATGGATCGGTTTCCACCCCTATGTGCTGGCGCTGGCGGGC
GGGCTGAACCTGATCTACCAGTTCTGGATACATACCGAGGCGGTCGACAAGATGCCCCGCTGGTTTGAGGCCGTGATGAA
CACGCCCTCTCATCACAGGGTCCACCACGCTACCAATCCGCGTTACCTCGACACCAACTATGCCGGCGTTTTCATCATAT
GGGACAAGATGTTCGGGACGTTTGTGCCCGAGCGGGAAGATGACAAGCCGAGCTATGGCATCGTCAAACAGCTATCGACC
CACAATCCTTTCACCATCGCCTTCCATGAGTTTGGAGGCTTCCTGAGGGATTGTGCAAGCGACGGCCTGCGGCCGTGGCG
CTGGATGGGCCGGGCGGTGAATGCGCCGGGCTGGACCCCTGATGGAGCGCACAATCGCTCCGTGGAGCTGAAGCAGGCAT
TTGTCGCGGCACATCCGGAACAAGCCGGACAGCCCGGATTGCCAGCGGGACTGCACGTGTCACAACCAGGACAAATCCGG
ACAAATCTGGACAAATCCGGTCAGCACTGA

Upstream 100 bases:

>100_bases
CATGCAACGCCTTGCCGATGTGGAGTTCGTGATGAAGGGCGGGGTCGTCTACAAGCAGGACGGCGCGCCGCAGGCCCCGT
CATTCTAGGGCTTTGCCATC

Downstream 100 bases:

>100_bases
TCCCGCCCTGGGCCTCTCATGGTTCCCCCTGGAGGTCAGGATGGAGCGCCCCGCCAGCCGGGCGCCGCCGCGAGGGCGAA
GAAGCGATCCACATCAAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MEFTPFPDVTALAAPVFVASVAWEWWAVKTGRAKGRYETKDALASMSMGLGNVVVNTLTGTIALWMMMLAWPYRVATIPF
AWWSFALCFVVYDLIYYWKHRFAHRMRWFWMEHVTHHSSQHYNLTTALRQPWFGPFTGLILVGLPLVWIGFHPYVLALAG
GLNLIYQFWIHTEAVDKMPRWFEAVMNTPSHHRVHHATNPRYLDTNYAGVFIIWDKMFGTFVPEREDDKPSYGIVKQLST
HNPFTIAFHEFGGFLRDCASDGLRPWRWMGRAVNAPGWTPDGAHNRSVELKQAFVAAHPEQAGQPGLPAGLHVSQPGQIR
TNLDKSGQH

Sequences:

>Translated_329_residues
MEFTPFPDVTALAAPVFVASVAWEWWAVKTGRAKGRYETKDALASMSMGLGNVVVNTLTGTIALWMMMLAWPYRVATIPF
AWWSFALCFVVYDLIYYWKHRFAHRMRWFWMEHVTHHSSQHYNLTTALRQPWFGPFTGLILVGLPLVWIGFHPYVLALAG
GLNLIYQFWIHTEAVDKMPRWFEAVMNTPSHHRVHHATNPRYLDTNYAGVFIIWDKMFGTFVPEREDDKPSYGIVKQLST
HNPFTIAFHEFGGFLRDCASDGLRPWRWMGRAVNAPGWTPDGAHNRSVELKQAFVAAHPEQAGQPGLPAGLHVSQPGQIR
TNLDKSGQH
>Mature_329_residues
MEFTPFPDVTALAAPVFVASVAWEWWAVKTGRAKGRYETKDALASMSMGLGNVVVNTLTGTIALWMMMLAWPYRVATIPF
AWWSFALCFVVYDLIYYWKHRFAHRMRWFWMEHVTHHSSQHYNLTTALRQPWFGPFTGLILVGLPLVWIGFHPYVLALAG
GLNLIYQFWIHTEAVDKMPRWFEAVMNTPSHHRVHHATNPRYLDTNYAGVFIIWDKMFGTFVPEREDDKPSYGIVKQLST
HNPFTIAFHEFGGFLRDCASDGLRPWRWMGRAVNAPGWTPDGAHNRSVELKQAFVAAHPEQAGQPGLPAGLHVSQPGQIR
TNLDKSGQH

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=248, Percent_Identity=40.3225806451613, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI25144659, Length=267, Percent_Identity=34.4569288389513, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 37651; Mature: 37651

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTPFPDVTALAAPVFVASVAWEWWAVKTGRAKGRYETKDALASMSMGLGNVVVNTLTG
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
TIALWMMMLAWPYRVATIPFAWWSFALCFVVYDLIYYWKHRFAHRMRWFWMEHVTHHSSQ
HHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYNLTTALRQPWFGPFTGLILVGLPLVWIGFHPYVLALAGGLNLIYQFWIHTEAVDKMPR
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFEAVMNTPSHHRVHHATNPRYLDTNYAGVFIIWDKMFGTFVPEREDDKPSYGIVKQLST
HHHHHHCCCCCCEEECCCCCCEECCCCCEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHCC
HNPFTIAFHEFGGFLRDCASDGLRPWRWMGRAVNAPGWTPDGAHNRSVELKQAFVAAHPE
CCCEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCH
QAGQPGLPAGLHVSQPGQIRTNLDKSGQH
HCCCCCCCCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MEFTPFPDVTALAAPVFVASVAWEWWAVKTGRAKGRYETKDALASMSMGLGNVVVNTLTG
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
TIALWMMMLAWPYRVATIPFAWWSFALCFVVYDLIYYWKHRFAHRMRWFWMEHVTHHSSQ
HHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYNLTTALRQPWFGPFTGLILVGLPLVWIGFHPYVLALAGGLNLIYQFWIHTEAVDKMPR
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFEAVMNTPSHHRVHHATNPRYLDTNYAGVFIIWDKMFGTFVPEREDDKPSYGIVKQLST
HHHHHHCCCCCCEEECCCCCCEECCCCCEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHCC
HNPFTIAFHEFGGFLRDCASDGLRPWRWMGRAVNAPGWTPDGAHNRSVELKQAFVAAHPE
CCCEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCH
QAGQPGLPAGLHVSQPGQIRTNLDKSGQH
HCCCCCCCCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]