Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 114797628

GI number: 114797628

Start: 3196199

End: 3197392

Strand: Reverse

Name: mraY

Synonym: HNE_3027

Alternate gene names: 114797628

Gene position: 3197392-3196199 (Counterclockwise)

Preceding gene: 114799693

Following gene: 114798168

Centisome position: 86.3

GC content: 62.73

Gene sequence:

>1194_bases
ATGCTGTACGAACTGCTGGCCGCAGACAGCGGTCTCTTCAACCTGCTGAACTACATCACCTTCCGCACAGGTGCGGCGGT
CGTCACTGCATTTCTGGTGACGGTTCTGTTCGGCGACATGCTGATCAATTTCCTGCGCGCCCGTCAGGGCAAGGGCCAGC
CGATCCGCGACCTGTCGCTGGAAATGCAGCTGTCCAAGCAGGGCACGCCCACCATGGGCGGCTTTCTCATCTGGCTGGGC
CTGATTGTCGGCGTGGCGCTGTGGGGCAACCTTCAGAACCCTTACGTCTGGGTCACCCTGTTCGTCACCTTCTCCTATGC
CATCCTCGGCTTCCTGGATGACTATGCCAAGGTCACCAAGCAGTCGACCGACGGCGTGTCTGCCGGCGCGCGGCTGATTG
CGGGCTTTGGTATTGCCGCGCTTGCCTGCGCCATCATCATGGGCCTGCACGGCGCCCACACCCCGGCGGGCCATGCCGAA
TGGGGCCCGTTCAATCCGCTGGCGGAATGGATTGCAGGCTTTGCGCCGCAGACCTCTGTTGAGCCGGCCGATCCCAACTT
CTCGGGCGGCGTCGCCGTGCCCTTCGTCAACAACTACTTCCTGCCGCTCGGTGGCTTCTTCATCCTCTTCGGCATGATCG
TCATCGTCGGGGCGGCCAATGCGGTGAACTTCACCGATGGCCTCGACGGCCTCGCCATCGTGCCGATGACATTCGCCGCC
GCCGCCTATGCGATGATTGCCTACCTGACAGGTAACTTTGTGTTCGCGTCCTATCTCGGCATCCAGTTTGCGCCGGGGGC
AGGCGAGCTGGCCGTGCTCCTCGGCGCGCTGATCGGCTCGGGCATGGGTTTCCTCTGGTACAATGCCTATCCGGCAAAGG
TCTTCATGGGCGACACCGGCTCGCTCGGCCTTGGCGGCATGCTCGGCGTCGTAGCTGTTGCGACCAAGCACGAGTTTGCG
CTGGTGGTGATCGGTGGCCTCTTCGTGATCGAGGCGGTTTCGGTGCTGACGCAGATCGGCTGGTTCAAGATCACCAAGCG
CCTGACGGGTGAGGGCAAGCGCATCTTCCTGATGGCGCCGCTGCACCACCACTTCCAGAAAAAGAACTGGCCGGAAACGC
GCGTTGTCGTGCGCTTCTGGATACTCTCCGTCCTGTTCGCCCTCGCGGGCCTCGCCACGCTGAAGCTGAGGTAA

Upstream 100 bases:

>100_bases
CCGGGATGGGTCGAATAGCGGACCGGCTGCGCCAATGGAGCGTGCCGGCCGGATTGGGCAAGATGGATGGCGGTCCAGAA
GGGGCTGCGAGGGTAAGCTG

Downstream 100 bases:

>100_bases
CCCGCGCGCCATGATCCCCATTACCGAATACGCTGGAAAAGACGTTGCGGTGTACGGCCTTGGCCGCTCCGGTCTCAGCG
CGGCCAAAGCCCTCAAGGCT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLYELLAADSGLFNLLNYITFRTGAAVVTAFLVTVLFGDMLINFLRARQGKGQPIRDLSLEMQLSKQGTPTMGGFLIWLG
LIVGVALWGNLQNPYVWVTLFVTFSYAILGFLDDYAKVTKQSTDGVSAGARLIAGFGIAALACAIIMGLHGAHTPAGHAE
WGPFNPLAEWIAGFAPQTSVEPADPNFSGGVAVPFVNNYFLPLGGFFILFGMIVIVGAANAVNFTDGLDGLAIVPMTFAA
AAYAMIAYLTGNFVFASYLGIQFAPGAGELAVLLGALIGSGMGFLWYNAYPAKVFMGDTGSLGLGGMLGVVAVATKHEFA
LVVIGGLFVIEAVSVLTQIGWFKITKRLTGEGKRIFLMAPLHHHFQKKNWPETRVVVRFWILSVLFALAGLATLKLR

Sequences:

>Translated_397_residues
MLYELLAADSGLFNLLNYITFRTGAAVVTAFLVTVLFGDMLINFLRARQGKGQPIRDLSLEMQLSKQGTPTMGGFLIWLG
LIVGVALWGNLQNPYVWVTLFVTFSYAILGFLDDYAKVTKQSTDGVSAGARLIAGFGIAALACAIIMGLHGAHTPAGHAE
WGPFNPLAEWIAGFAPQTSVEPADPNFSGGVAVPFVNNYFLPLGGFFILFGMIVIVGAANAVNFTDGLDGLAIVPMTFAA
AAYAMIAYLTGNFVFASYLGIQFAPGAGELAVLLGALIGSGMGFLWYNAYPAKVFMGDTGSLGLGGMLGVVAVATKHEFA
LVVIGGLFVIEAVSVLTQIGWFKITKRLTGEGKRIFLMAPLHHHFQKKNWPETRVVVRFWILSVLFALAGLATLKLR
>Mature_397_residues
MLYELLAADSGLFNLLNYITFRTGAAVVTAFLVTVLFGDMLINFLRARQGKGQPIRDLSLEMQLSKQGTPTMGGFLIWLG
LIVGVALWGNLQNPYVWVTLFVTFSYAILGFLDDYAKVTKQSTDGVSAGARLIAGFGIAALACAIIMGLHGAHTPAGHAE
WGPFNPLAEWIAGFAPQTSVEPADPNFSGGVAVPFVNNYFLPLGGFFILFGMIVIVGAANAVNFTDGLDGLAIVPMTFAA
AAYAMIAYLTGNFVFASYLGIQFAPGAGELAVLLGALIGSGMGFLWYNAYPAKVFMGDTGSLGLGGMLGVVAVATKHEFA
LVVIGGLFVIEAVSVLTQIGWFKITKRLTGEGKRIFLMAPLHHHFQKKNWPETRVVVRFWILSVLFALAGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=385, Percent_Identity=43.6363636363636, Blast_Score=305, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_HYPNA (Q0BXT9)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761704.1
- STRING:   Q0BXT9
- GeneID:   4288650
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_3027
- NMPDR:   fig|228405.5.peg.2902
- TIGR:   HNE_3027
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q0BXT9
- ProtClustDB:   CLSK2531693
- BioCyc:   HNEP81032:HNE_3027-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 42416; Mature: 42416

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x142c89dc)-; HASH(0x15eb1154)-; HASH(0xfc7d6cc)-; HASH(0x1593cf7c)-; HASH(0x14fbf60c)-; HASH(0x15ee466c)-; HASH(0x15ae4d18)-; HASH(0x157c4368)-; HASH(0x14eb22f4)-; HASH(0x1413749c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA