Click here to switch to the map view.

The map label for this gene is yfgC [H]

Identifier: 114797419

GI number: 114797419

Start: 653440

End: 654411

Strand: Direct

Name: yfgC [H]

Synonym: HNE_0650

Alternate gene names: 114797419

Gene position: 653440-654411 (Clockwise)

Preceding gene: 114797333

Following gene: 114798400

Centisome position: 17.64

GC content: 63.68

Gene sequence:

>972_bases
ATGCAGCCACCCCAGCAACCGATCCGCGCCAATGGCCTCGGCGATCTTGTCGGCGGGCGCGGCGGCATCATTCTGATCGC
CCTGATCGGCCTGTTCATCTACTGGCAGTCAAACCAGAAAGAGGTGCCCTTCGCGCCCGGCAAGAAGCAGTTCAACACCC
TGTCGGTCGCGCAGGAGATCAAGCTGGGCGAGGAATCCTATCTTCAGATCCTTCAGCAGGAGCAGGGGCAGGGCAACACG
GTTCTCTGCGCCGATGAGGCGAGCTGTCAGGGAGACGCCCGTGTGCTGACGGAAAAGGTGCGCGCCATCGGCACGCGCCT
GCAACGCGCGGCGCTGGAGCTGGAAAACGATTACCGCACCGAGGGCTATGACATGCCCGGCGTGGTGGAGCAGTTCGACT
GGACCTATTATGTCGTCGACTCGCCCACGCCCAACGCCTTCTGCCTGCCGGGCGGCTATGTGGCAGTCTATACCGGCATC
CTCGATATCACTGGCAACTATGACGGCCTCGTCACGCTCGATGATGTTGCCGACGAGAACAAGCTTGCCGTCGTCATGGG
TCATGAAATCGGCCACGCCCTCGCCCATCACGGCGCCGCGCGGATGAGCACCCAGCAGATGATGCAGATCGGCCAGGTCG
CGCTCGCCGTGGGGGTAGGGGATATGGACGCCGGCCAGCGGCTGGCGGTGCTTCAGGCGTTTGGTGTTGCCGCCCAGGGC
GGCTTCCTAGCCTTCTCGCGCGATCATGAAACACAGGCTGACAAGATCGGCCTCGATCTGCTCGTGCGCGCCTGTTACGA
TCCCCGCCAGGCGCCCGAACTCTGGGAGCGGATGGGCGAGATTGGCGAAGGCCAGCGCCCCCCCGAATGGATGAGCACCC
ACCCGGCCTCTGAAACCCGCGCTGAAAACTTCCGCAAATGGATGCCGGACGCCATCGCGGAATATGAGCGCCGCTGTGGC
GCGCTCGATTAA

Upstream 100 bases:

>100_bases
AGCGATCCCGGCCTTTGGCGCAATGCGGCGTGTCCTGTCTTTTCGCTCGCCAGACGCTGGGTTAACTGGTTTGTTAGCCA
CCTTTTCAGGAGCGCAAACG

Downstream 100 bases:

>100_bases
AAACGGCCCCCGCAGCAAAGCGAGGGCCGCAAAGGGCCATTCCCCAACGTGGAAAAGCGCGACCTTGGGAGCTGCGCCTT
TCGCCCTTTGAATCTGAGTA

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQPPQQPIRANGLGDLVGGRGGIILIALIGLFIYWQSNQKEVPFAPGKKQFNTLSVAQEIKLGEESYLQILQQEQGQGNT
VLCADEASCQGDARVLTEKVRAIGTRLQRAALELENDYRTEGYDMPGVVEQFDWTYYVVDSPTPNAFCLPGGYVAVYTGI
LDITGNYDGLVTLDDVADENKLAVVMGHEIGHALAHHGAARMSTQQMMQIGQVALAVGVGDMDAGQRLAVLQAFGVAAQG
GFLAFSRDHETQADKIGLDLLVRACYDPRQAPELWERMGEIGEGQRPPEWMSTHPASETRAENFRKWMPDAIAEYERRCG
ALD

Sequences:

>Translated_323_residues
MQPPQQPIRANGLGDLVGGRGGIILIALIGLFIYWQSNQKEVPFAPGKKQFNTLSVAQEIKLGEESYLQILQQEQGQGNT
VLCADEASCQGDARVLTEKVRAIGTRLQRAALELENDYRTEGYDMPGVVEQFDWTYYVVDSPTPNAFCLPGGYVAVYTGI
LDITGNYDGLVTLDDVADENKLAVVMGHEIGHALAHHGAARMSTQQMMQIGQVALAVGVGDMDAGQRLAVLQAFGVAAQG
GFLAFSRDHETQADKIGLDLLVRACYDPRQAPELWERMGEIGEGQRPPEWMSTHPASETRAENFRKWMPDAIAEYERRCG
ALD
>Mature_323_residues
MQPPQQPIRANGLGDLVGGRGGIILIALIGLFIYWQSNQKEVPFAPGKKQFNTLSVAQEIKLGEESYLQILQQEQGQGNT
VLCADEASCQGDARVLTEKVRAIGTRLQRAALELENDYRTEGYDMPGVVEQFDWTYYVVDSPTPNAFCLPGGYVAVYTGI
LDITGNYDGLVTLDDVADENKLAVVMGHEIGHALAHHGAARMSTQQMMQIGQVALAVGVGDMDAGQRLAVLQAFGVAAQG
GFLAFSRDHETQADKIGLDLLVRACYDPRQAPELWERMGEIGEGQRPPEWMSTHPASETRAENFRKWMPDAIAEYERRCG
ALD

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=195, Percent_Identity=32.3076923076923, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1788840, Length=261, Percent_Identity=25.6704980842912, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322940, Length=303, Percent_Identity=29.3729372937294, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 35400; Mature: 35400

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPPQQPIRANGLGDLVGGRGGIILIALIGLFIYWQSNQKEVPFAPGKKQFNTLSVAQEI
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHH
KLGEESYLQILQQEQGQGNTVLCADEASCQGDARVLTEKVRAIGTRLQRAALELENDYRT
HCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGYDMPGVVEQFDWTYYVVDSPTPNAFCLPGGYVAVYTGILDITGNYDGLVTLDDVADEN
CCCCCCCHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEHEEECCCCCCEEEECCCCCCC
KLAVVMGHEIGHALAHHGAARMSTQQMMQIGQVALAVGVGDMDAGQRLAVLQAFGVAAQG
CEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHCCC
GFLAFSRDHETQADKIGLDLLVRACYDPRQAPELWERMGEIGEGQRPPEWMSTHPASETR
CEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCHHH
AENFRKWMPDAIAEYERRCGALD
HHHHHHHCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQPPQQPIRANGLGDLVGGRGGIILIALIGLFIYWQSNQKEVPFAPGKKQFNTLSVAQEI
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHH
KLGEESYLQILQQEQGQGNTVLCADEASCQGDARVLTEKVRAIGTRLQRAALELENDYRT
HCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGYDMPGVVEQFDWTYYVVDSPTPNAFCLPGGYVAVYTGILDITGNYDGLVTLDDVADEN
CCCCCCCHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEHEEECCCCCCEEEECCCCCCC
KLAVVMGHEIGHALAHHGAARMSTQQMMQIGQVALAVGVGDMDAGQRLAVLQAFGVAAQG
CEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHCCC
GFLAFSRDHETQADKIGLDLLVRACYDPRQAPELWERMGEIGEGQRPPEWMSTHPASETR
CEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCHHH
AENFRKWMPDAIAEYERRCGALD
HHHHHHHCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]