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The map label for this gene is aat

Identifier: 114797414

GI number: 114797414

Start: 2352653

End: 2353429

Strand: Direct

Name: aat

Synonym: HNE_2251

Alternate gene names: 114797414

Gene position: 2352653-2353429 (Clockwise)

Preceding gene: 114798573

Following gene: 114799028

Centisome position: 63.5

GC content: 62.03

Gene sequence:

>777_bases
ATGTCAGCCCGCTTCGGACCAGAAGACCTGCTCGCCTGCTATCGCCGGGGCGTATTTCCGATGGCCGATTCGCGGGACGA
TCCCCGGCTGTTCCTCGTTGATCCGGACTTCAGGGGCATTCTTCCCCTTGACGCATTCCACATCCCCAAACGCCTGAAGC
GCCGCGTCTGCCAGGACCCGTATCGCGTTAGCTTCGATACCGCCTTCACCCGCGTCGTCGAAGCCTGCGGCGAGCCGCAC
GACAACCGGCCAAACACCTGGATCAACTCCCCCATCGTGAACCTCTACAGCGCATTGCACCGGCAAGGCTTCGCCCACTC
GGTAGAGTGCTGGGACGGGGATCAATTGGTAGGCGGGCTCTATGGCGTGTCCCTGGGCGGCGCCTTTTTCGGCGAGAGCA
TGTTCTCCCGTGCGACGGACGCGTCAAAGATCGCCCTCGTCCACCTTGCCGCCCGTCTGATCGACCGGGGCTATGTGCTG
CTGGACGCGCAATTCCACAATCCGCATCTCACCCAGTTCGGCCTGATCGAAATCAGCCGTGACGCTTTCAAAGCGCGCCT
GAAAGCCGCCCTCAAAGTGGGAGCAGATTTTCATGGCGGCTCTGACGGGCCAGCGCCCGATCAATCTATAGGGATGTCTT
CGTCCGGCGGTGTTTCGGACTCGGTCACGCCTGCGGGCATGTCCTCATACAGCGGCTCTTCGCTTTCCGGAATGATCGCG
CGCTCAGGCAGCTTCACCGGATCGGGCGCCGTGCAGCGAATAACCCAGATGTCGTAG

Upstream 100 bases:

>100_bases
CGAAAAGTTCCTGGCCGAGAACAAGCTGCCGGCGGGCGAATAGCCCGCCCGGCATCCCGCCACATTTACAGCCTGCGCGG
CGCAACCCATATCTTTGGTC

Downstream 100 bases:

>100_bases
ACGGGATGCTCCAGCGCATTCAGGCCGGGCGAGGACGCATACATCCAGCCCGAAAACAGGATCGGGCTATCGGCTTCAGA
CGGCGGCACATCCTTGGCCG

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSARFGPEDLLACYRRGVFPMADSRDDPRLFLVDPDFRGILPLDAFHIPKRLKRRVCQDPYRVSFDTAFTRVVEACGEPH
DNRPNTWINSPIVNLYSALHRQGFAHSVECWDGDQLVGGLYGVSLGGAFFGESMFSRATDASKIALVHLAARLIDRGYVL
LDAQFHNPHLTQFGLIEISRDAFKARLKAALKVGADFHGGSDGPAPDQSIGMSSSGGVSDSVTPAGMSSYSGSSLSGMIA
RSGSFTGSGAVQRITQMS

Sequences:

>Translated_258_residues
MSARFGPEDLLACYRRGVFPMADSRDDPRLFLVDPDFRGILPLDAFHIPKRLKRRVCQDPYRVSFDTAFTRVVEACGEPH
DNRPNTWINSPIVNLYSALHRQGFAHSVECWDGDQLVGGLYGVSLGGAFFGESMFSRATDASKIALVHLAARLIDRGYVL
LDAQFHNPHLTQFGLIEISRDAFKARLKAALKVGADFHGGSDGPAPDQSIGMSSSGGVSDSVTPAGMSSYSGSSLSGMIA
RSGSFTGSGAVQRITQMS
>Mature_257_residues
SARFGPEDLLACYRRGVFPMADSRDDPRLFLVDPDFRGILPLDAFHIPKRLKRRVCQDPYRVSFDTAFTRVVEACGEPHD
NRPNTWINSPIVNLYSALHRQGFAHSVECWDGDQLVGGLYGVSLGGAFFGESMFSRATDASKIALVHLAARLIDRGYVLL
DAQFHNPHLTQFGLIEISRDAFKARLKAALKVGADFHGGSDGPAPDQSIGMSSSGGVSDSVTPAGMSSYSGSSLSGMIAR
SGSFTGSGAVQRITQMS

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=176, Percent_Identity=43.1818181818182, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_HYPNA (Q0BZZ7)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760946.1
- ProteinModelPortal:   Q0BZZ7
- SMR:   Q0BZZ7
- STRING:   Q0BZZ7
- GeneID:   4287680
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2251
- NMPDR:   fig|228405.5.peg.2170
- TIGR:   HNE_2251
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   EWISDEL
- PhylomeDB:   Q0BZZ7
- ProtClustDB:   PRK00301
- BioCyc:   HNEP81032:HNE_2251-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 27891; Mature: 27760

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARFGPEDLLACYRRGVFPMADSRDDPRLFLVDPDFRGILPLDAFHIPKRLKRRVCQDP
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
YRVSFDTAFTRVVEACGEPHDNRPNTWINSPIVNLYSALHRQGFAHSVECWDGDQLVGGL
CEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
YGVSLGGAFFGESMFSRATDASKIALVHLAARLIDRGYVLLDAQFHNPHLTQFGLIEISR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEHEEECH
DAFKARLKAALKVGADFHGGSDGPAPDQSIGMSSSGGVSDSVTPAGMSSYSGSSLSGMIA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEE
RSGSFTGSGAVQRITQMS
CCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SARFGPEDLLACYRRGVFPMADSRDDPRLFLVDPDFRGILPLDAFHIPKRLKRRVCQDP
CCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
YRVSFDTAFTRVVEACGEPHDNRPNTWINSPIVNLYSALHRQGFAHSVECWDGDQLVGGL
CEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
YGVSLGGAFFGESMFSRATDASKIALVHLAARLIDRGYVLLDAQFHNPHLTQFGLIEISR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEHEEECH
DAFKARLKAALKVGADFHGGSDGPAPDQSIGMSSSGGVSDSVTPAGMSSYSGSSLSGMIA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEE
RSGSFTGSGAVQRITQMS
CCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA