Definition Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession NC_008358
Length 3,705,021

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The map label for this gene is ftsH [H]

Identifier: 114797326

GI number: 114797326

Start: 139957

End: 141876

Strand: Direct

Name: ftsH [H]

Synonym: HNE_0158

Alternate gene names: 114797326

Gene position: 139957-141876 (Clockwise)

Preceding gene: 114799417

Following gene: 114800066

Centisome position: 3.78

GC content: 61.25

Gene sequence:

>1920_bases
ATGAATGTCCGGAATTTGGCGATCTGGGGCGCGCTCGCCCTGCTTGTGATCGGTATGGCTGTTATGATGGGCGGCAACCC
TGAAGTTGCCCGCGCCGATCCGACTAAGCTGTCCGAGATCTATCAGCTGGCAGAAGACGGCAAACTTGCCGACGCCACGC
TGGGCGACACCACGATCATCGCCAAGACCACCGACGGCCGCACGCTGAAAAGCGAGCTGCGCGCGCTGGACATGAAAACC
GAAGATATTCTCACTCAGAACAATGTTCCTTTCTCGGTGAAGCCCGATACGGGCCGCAACAATGTGGCCTCCGTACTCCT
GTCGCTTTTGCCGATCCTGCTGATCGTCGGCTTTGTCTTCTTCATGATGCGCCAGATGCAGGGTGGGGGCACCCGCGGCG
CCATGAGCTTTGGCAAGTCGCGGGCGCGCCTGCTGACCGAAAAGCATGGACGCGTCACCTTTGATGACGTGGCCGGTGTG
GATGAGGCAAAGGAAGAACTCCAGGAAATCGTTGAGTTCCTGCAAGACCCTTCCAAGTTCCAGCGCCTGGGCGGCAAAAT
TCCGAAAGGCGCGCTGCTGGTCGGCCCGCCCGGTACAGGTAAAACCCTGCTTGCGCGCGCTGTTGCCGGCGAAGCTGGTG
TGCCGTTCTTCACGATTTCCGGTTCTGACTTCGTCGAAATGTTCGTCGGCGTTGGCGCCAGCCGCGTCCGCGACATGTTC
GAGCAGGCCAAGCGCTCGGCGCCTTGCATCATCTTCATCGACGAAATTGATGCCGTTGGCCGCTCACGCGGCGCAGGCCT
CGGCGGCGGCAATGACGAACGCGAGCAGACGCTGAACCAGCTCCTCGTCGAGATGGATGGTTTTGAGGCCAATGAAGGCA
TCATCATCATGGCGGCCACCAACCGCCCGGATGTGCTCGACCCTGCGCTGCTGCGCCCCGGCCGGTTTGACCGTCAGGTG
ACTGTTGGCAATCCTGACATAATCGGCCGCGAGAAGATCCTGCGCGTTCACATGCGCAATGTGCCGCTCGCCAAGGATGT
CGAGACCAAGACGATCGCGCGCGGTACGCCCGGCTTTTCCGGCGCTGACCTCGCCAACCTCGTGAACGAGGCCGCTCTCC
TGGCGGCACGCCGCGGCAAACGTGTCGTTGCGATGCAGGAATTTGAGGACGCCAAGGACAAGGTGCTTATGGGGCCAGAG
CGCCGCTCGATGGTCATGTCGGAGAAGGAAAAGATCCTGACCGCCTGGCACGAGGCCGGCCACGCTGTTGTGGCGATGAA
AGTGCCTGCTGCCGATCCCGTTCATAAGGCGACGATCATTCCGCGCGGCCGGGCTCTCGGCATGGTCATGCAGCTGCCCG
AAGACGACAAGCTGTCGATGTCCAAGGTCGAGATGACTTCGCGCCTGGCCATCATCATGGGCGGCCGGGTCGCCGAGGAA
CTGAAGTTCGGAGATGACAATGTCACCGCCGGCGCTGCCTCCGACATCCAGCAGGCCACACGGCTCGCCCGCGCGATGGT
CACACGCTGGGGCTATTCGGACATCATCGGCCCGGTTGATTACGGCTCGGATCAGGGCGACGTGTTCCTGGGCCAGCAGC
TCATGCAGTCCAGCCATATCTCGGAAGATACCTCGCGCAAGATCGAGGAAGAAGTCCGTAAGCTGATTGAAAAGGGCAAG
GAAGACGCCCGGCAGGTCATGACGGAGTTCCGCAAGGAATGGGAAGCGATCGCGACCGGTCTGCTCGAATTCGAAACGCT
GACGGGTGAAGAGATTGCCGGCCTGCTGAAAGGTACGCCGCCGAGCCGTCCGGATATTTCCGATGACGACGCAGGCCCTG
CCTCTGCTGTTCCGGTCATCGGTAAGCGCAAGAAGCCGAAAGATGACGGCATTGGCGACGCAGAACCCAATCCGGCCTGA

Upstream 100 bases:

>100_bases
CGCATCAGCAGGAAAGGAGTCGTTTTTAGAGGATTTGGTGCCTATCTTCTAAACTCGTTCCCGTATGGTGGATCGAGTAG
TTTCTGACGGAACCAACGCT

Downstream 100 bases:

>100_bases
CGCCATACAACCACATAGACAAAGCCCTTCCGGTTCACCGGGAGGGCTTTTCTTATCTGGGTGTGGTCCTGGCGTGGACT
TCCGGGCGCTTGCCTTTCCT

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MNVRNLAIWGALALLVIGMAVMMGGNPEVARADPTKLSEIYQLAEDGKLADATLGDTTIIAKTTDGRTLKSELRALDMKT
EDILTQNNVPFSVKPDTGRNNVASVLLSLLPILLIVGFVFFMMRQMQGGGTRGAMSFGKSRARLLTEKHGRVTFDDVAGV
DEAKEELQEIVEFLQDPSKFQRLGGKIPKGALLVGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMF
EQAKRSAPCIIFIDEIDAVGRSRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIMAATNRPDVLDPALLRPGRFDRQV
TVGNPDIIGREKILRVHMRNVPLAKDVETKTIARGTPGFSGADLANLVNEAALLAARRGKRVVAMQEFEDAKDKVLMGPE
RRSMVMSEKEKILTAWHEAGHAVVAMKVPAADPVHKATIIPRGRALGMVMQLPEDDKLSMSKVEMTSRLAIIMGGRVAEE
LKFGDDNVTAGAASDIQQATRLARAMVTRWGYSDIIGPVDYGSDQGDVFLGQQLMQSSHISEDTSRKIEEEVRKLIEKGK
EDARQVMTEFRKEWEAIATGLLEFETLTGEEIAGLLKGTPPSRPDISDDDAGPASAVPVIGKRKKPKDDGIGDAEPNPA

Sequences:

>Translated_639_residues
MNVRNLAIWGALALLVIGMAVMMGGNPEVARADPTKLSEIYQLAEDGKLADATLGDTTIIAKTTDGRTLKSELRALDMKT
EDILTQNNVPFSVKPDTGRNNVASVLLSLLPILLIVGFVFFMMRQMQGGGTRGAMSFGKSRARLLTEKHGRVTFDDVAGV
DEAKEELQEIVEFLQDPSKFQRLGGKIPKGALLVGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMF
EQAKRSAPCIIFIDEIDAVGRSRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIMAATNRPDVLDPALLRPGRFDRQV
TVGNPDIIGREKILRVHMRNVPLAKDVETKTIARGTPGFSGADLANLVNEAALLAARRGKRVVAMQEFEDAKDKVLMGPE
RRSMVMSEKEKILTAWHEAGHAVVAMKVPAADPVHKATIIPRGRALGMVMQLPEDDKLSMSKVEMTSRLAIIMGGRVAEE
LKFGDDNVTAGAASDIQQATRLARAMVTRWGYSDIIGPVDYGSDQGDVFLGQQLMQSSHISEDTSRKIEEEVRKLIEKGK
EDARQVMTEFRKEWEAIATGLLEFETLTGEEIAGLLKGTPPSRPDISDDDAGPASAVPVIGKRKKPKDDGIGDAEPNPA
>Mature_639_residues
MNVRNLAIWGALALLVIGMAVMMGGNPEVARADPTKLSEIYQLAEDGKLADATLGDTTIIAKTTDGRTLKSELRALDMKT
EDILTQNNVPFSVKPDTGRNNVASVLLSLLPILLIVGFVFFMMRQMQGGGTRGAMSFGKSRARLLTEKHGRVTFDDVAGV
DEAKEELQEIVEFLQDPSKFQRLGGKIPKGALLVGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMF
EQAKRSAPCIIFIDEIDAVGRSRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIMAATNRPDVLDPALLRPGRFDRQV
TVGNPDIIGREKILRVHMRNVPLAKDVETKTIARGTPGFSGADLANLVNEAALLAARRGKRVVAMQEFEDAKDKVLMGPE
RRSMVMSEKEKILTAWHEAGHAVVAMKVPAADPVHKATIIPRGRALGMVMQLPEDDKLSMSKVEMTSRLAIIMGGRVAEE
LKFGDDNVTAGAASDIQQATRLARAMVTRWGYSDIIGPVDYGSDQGDVFLGQQLMQSSHISEDTSRKIEEEVRKLIEKGK
EDARQVMTEFRKEWEAIATGLLEFETLTGEEIAGLLKGTPPSRPDISDDDAGPASAVPVIGKRKKPKDDGIGDAEPNPA

Specific function: Absence of FtsH leads to increased sigma-32 levels, which suggests, in analogy to E.coli, that sigma-32 is a substrate for FtsH. May play a role in the general stress response, as overexpression leads to improved resistance to salt stress [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI7657689, Length=447, Percent_Identity=52.7964205816555, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI21327685, Length=447, Percent_Identity=52.7964205816555, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI300192933, Length=508, Percent_Identity=47.4409448818898, Blast_Score=450, Evalue=1e-126,
Organism=Homo sapiens, GI4507173, Length=531, Percent_Identity=40.30131826742, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI4506209, Length=251, Percent_Identity=42.2310756972112, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI24497435, Length=262, Percent_Identity=42.3664122137405, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=42.4778761061947, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI195539395, Length=250, Percent_Identity=42, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI21361144, Length=236, Percent_Identity=42.7966101694915, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=40.7272727272727, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=40.7272727272727, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI24430151, Length=251, Percent_Identity=39.4422310756972, Blast_Score=195, Evalue=9e-50,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=42.2222222222222, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI89064750, Length=259, Percent_Identity=37.8378378378378, Blast_Score=183, Evalue=5e-46,
Organism=Homo sapiens, GI24430155, Length=259, Percent_Identity=37.8378378378378, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI5729991, Length=259, Percent_Identity=37.8378378378378, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI40806173, Length=210, Percent_Identity=47.1428571428571, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI229577436, Length=244, Percent_Identity=41.3934426229508, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4505725, Length=226, Percent_Identity=39.3805309734513, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI194018488, Length=250, Percent_Identity=40, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI24497618, Length=234, Percent_Identity=39.3162393162393, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI153792536, Length=234, Percent_Identity=39.3162393162393, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI5901990, Length=245, Percent_Identity=38.7755102040816, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI14149767, Length=277, Percent_Identity=35.3790613718412, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI62177112, Length=277, Percent_Identity=35.3790613718412, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI7019569, Length=261, Percent_Identity=35.632183908046, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=35.4430379746835, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI17865802, Length=233, Percent_Identity=37.3390557939914, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI11875211, Length=229, Percent_Identity=41.0480349344978, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI40806170, Length=229, Percent_Identity=41.0480349344978, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI156564401, Length=219, Percent_Identity=39.2694063926941, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI31377644, Length=245, Percent_Identity=34.6938775510204, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI31742536, Length=230, Percent_Identity=36.0869565217391, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI112789543, Length=230, Percent_Identity=36.0869565217391, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI310125280, Length=216, Percent_Identity=38.8888888888889, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310125282, Length=219, Percent_Identity=38.8127853881278, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI64084766, Length=308, Percent_Identity=28.8961038961039, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI116292174, Length=248, Percent_Identity=29.4354838709677, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI75677353, Length=192, Percent_Identity=32.8125, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI4757852, Length=162, Percent_Identity=30.2469135802469, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI119964730, Length=162, Percent_Identity=30.2469135802469, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1789568, Length=625, Percent_Identity=55.84, Blast_Score=694, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17554264, Length=482, Percent_Identity=46.6804979253112, Blast_Score=425, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI71994521, Length=466, Percent_Identity=47.6394849785408, Blast_Score=410, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115534323, Length=489, Percent_Identity=42.5357873210634, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17554786, Length=262, Percent_Identity=43.5114503816794, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI25144281, Length=262, Percent_Identity=43.1297709923664, Blast_Score=216, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=262, Percent_Identity=43.1297709923664, Blast_Score=216, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=253, Percent_Identity=42.6877470355731, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17532375, Length=247, Percent_Identity=39.2712550607287, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71987364, Length=250, Percent_Identity=41.6, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71987372, Length=250, Percent_Identity=41.6, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17508701, Length=239, Percent_Identity=43.0962343096234, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17505546, Length=252, Percent_Identity=42.0634920634921, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17531535, Length=242, Percent_Identity=43.3884297520661, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17563250, Length=251, Percent_Identity=40.2390438247012, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17508053, Length=244, Percent_Identity=42.2131147540984, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17537217, Length=260, Percent_Identity=39.2307692307692, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=38.2113821138211, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI25153574, Length=228, Percent_Identity=38.5964912280702, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=38.4955752212389, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=38.5593220338983, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI193206116, Length=236, Percent_Identity=38.5593220338983, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=236, Percent_Identity=38.5593220338983, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17570397, Length=164, Percent_Identity=43.9024390243902, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32566590, Length=164, Percent_Identity=43.9024390243902, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI86561515, Length=233, Percent_Identity=37.3390557939914, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=248, Percent_Identity=35.4838709677419, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=234, Percent_Identity=40.1709401709402, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=247, Percent_Identity=38.0566801619433, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17508421, Length=243, Percent_Identity=38.2716049382716, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=219, Percent_Identity=38.3561643835616, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI133901658, Length=219, Percent_Identity=38.3561643835616, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17541224, Length=238, Percent_Identity=36.1344537815126, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17541226, Length=238, Percent_Identity=36.1344537815126, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17560432, Length=231, Percent_Identity=35.4978354978355, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325281, Length=451, Percent_Identity=52.7716186252772, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6323736, Length=519, Percent_Identity=47.0134874759152, Blast_Score=451, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320854, Length=522, Percent_Identity=44.8275862068966, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=43.2950191570881, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=42.5196850393701, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6320077, Length=227, Percent_Identity=44.9339207048458, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=237, Percent_Identity=43.8818565400844, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=231, Percent_Identity=44.5887445887446, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=39.5918367346939, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=242, Percent_Identity=38.8429752066116, Blast_Score=173, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6323429, Length=245, Percent_Identity=39.5918367346939, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324000, Length=237, Percent_Identity=40.5063291139241, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6322994, Length=232, Percent_Identity=38.7931034482759, Blast_Score=168, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6321709, Length=269, Percent_Identity=37.9182156133829, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322651, Length=244, Percent_Identity=37.7049180327869, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6325431, Length=265, Percent_Identity=36.9811320754717, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=37.0833333333333, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319554, Length=240, Percent_Identity=35.4166666666667, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325183, Length=238, Percent_Identity=33.1932773109244, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320887, Length=251, Percent_Identity=34.2629482071713, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=190, Percent_Identity=28.4210526315789, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574878, Length=519, Percent_Identity=47.2061657032755, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24665814, Length=519, Percent_Identity=47.2061657032755, Blast_Score=444, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24658770, Length=445, Percent_Identity=48.314606741573, Blast_Score=433, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24639391, Length=457, Percent_Identity=43.7636761487965, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI161076486, Length=309, Percent_Identity=35.9223300970874, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI17137560, Length=309, Percent_Identity=35.9223300970874, Blast_Score=215, Evalue=7e-56,
Organism=Drosophila melanogaster, GI161076488, Length=243, Percent_Identity=41.1522633744856, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137738, Length=246, Percent_Identity=44.3089430894309, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=42.3664122137405, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=58.7878787878788, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24651451, Length=262, Percent_Identity=42.7480916030534, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI281365776, Length=232, Percent_Identity=44.3965517241379, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24660075, Length=232, Percent_Identity=44.3965517241379, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI45552965, Length=232, Percent_Identity=44.3965517241379, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=43.0962343096234, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24640100, Length=250, Percent_Identity=41.6, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24649446, Length=251, Percent_Identity=39.8406374501992, Blast_Score=195, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24663015, Length=250, Percent_Identity=40.4, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=42.4489795918367, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24652279, Length=271, Percent_Identity=36.1623616236162, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281361487, Length=239, Percent_Identity=38.9121338912134, Blast_Score=179, Evalue=7e-45,
Organism=Drosophila melanogaster, GI18860063, Length=239, Percent_Identity=38.9121338912134, Blast_Score=179, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=38.7096774193548, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=38.7096774193548, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281363136, Length=237, Percent_Identity=41.7721518987342, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI78707192, Length=237, Percent_Identity=41.7721518987342, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI281360144, Length=271, Percent_Identity=35.4243542435424, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360140, Length=271, Percent_Identity=35.4243542435424, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360136, Length=271, Percent_Identity=35.4243542435424, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644411, Length=271, Percent_Identity=35.4243542435424, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360142, Length=269, Percent_Identity=35.6877323420074, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357333, Length=269, Percent_Identity=35.6877323420074, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360146, Length=269, Percent_Identity=35.6877323420074, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360138, Length=269, Percent_Identity=35.6877323420074, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644145, Length=242, Percent_Identity=36.7768595041322, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859657, Length=234, Percent_Identity=38.8888888888889, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI20129529, Length=280, Percent_Identity=33.5714285714286, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21355121, Length=210, Percent_Identity=34.7619047619048, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI20129423, Length=234, Percent_Identity=36.3247863247863, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571849, Length=231, Percent_Identity=40.2597402597403, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28571847, Length=231, Percent_Identity=40.2597402597403, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573010, Length=241, Percent_Identity=36.5145228215768, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24581396, Length=233, Percent_Identity=37.3390557939914, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17864540, Length=241, Percent_Identity=36.5145228215768, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24639486, Length=190, Percent_Identity=34.2105263157895, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 69063; Mature: 69063

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNVRNLAIWGALALLVIGMAVMMGGNPEVARADPTKLSEIYQLAEDGKLADATLGDTTII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
AKTTDGRTLKSELRALDMKTEDILTQNNVPFSVKPDTGRNNVASVLLSLLPILLIVGFVF
EECCCCHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
FMMRQMQGGGTRGAMSFGKSRARLLTEKHGRVTFDDVAGVDEAKEELQEIVEFLQDPSKF
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHHHHHCHHHH
QRLGGKIPKGALLVGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMF
HHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHH
EQAKRSAPCIIFIDEIDAVGRSRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIMAAT
HHHHHCCCEEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRPDVLDPALLRPGRFDRQVTVGNPDIIGREKILRVHMRNVPLAKDVETKTIARGTPGFS
CCCCCCCHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
GADLANLVNEAALLAARRGKRVVAMQEFEDAKDKVLMGPERRSMVMSEKEKILTAWHEAG
CHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCC
HAVVAMKVPAADPVHKATIIPRGRALGMVMQLPEDDKLSMSKVEMTSRLAIIMGGRVAEE
CEEEEEECCCCCCCCCEEECCCCCHHHHEEECCCCCCCCHHHHHHHHHEEEEECCHHHHH
LKFGDDNVTAGAASDIQQATRLARAMVTRWGYSDIIGPVDYGSDQGDVFLGQQLMQSSHI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
SEDTSRKIEEEVRKLIEKGKEDARQVMTEFRKEWEAIATGLLEFETLTGEEIAGLLKGTP
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PSRPDISDDDAGPASAVPVIGKRKKPKDDGIGDAEPNPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVRNLAIWGALALLVIGMAVMMGGNPEVARADPTKLSEIYQLAEDGKLADATLGDTTII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
AKTTDGRTLKSELRALDMKTEDILTQNNVPFSVKPDTGRNNVASVLLSLLPILLIVGFVF
EECCCCHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
FMMRQMQGGGTRGAMSFGKSRARLLTEKHGRVTFDDVAGVDEAKEELQEIVEFLQDPSKF
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHHHHHCHHHH
QRLGGKIPKGALLVGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMF
HHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHH
EQAKRSAPCIIFIDEIDAVGRSRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIMAAT
HHHHHCCCEEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRPDVLDPALLRPGRFDRQVTVGNPDIIGREKILRVHMRNVPLAKDVETKTIARGTPGFS
CCCCCCCHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
GADLANLVNEAALLAARRGKRVVAMQEFEDAKDKVLMGPERRSMVMSEKEKILTAWHEAG
CHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCC
HAVVAMKVPAADPVHKATIIPRGRALGMVMQLPEDDKLSMSKVEMTSRLAIIMGGRVAEE
CEEEEEECCCCCCCCCEEECCCCCHHHHEEECCCCCCCCHHHHHHHHHEEEEECCHHHHH
LKFGDDNVTAGAASDIQQATRLARAMVTRWGYSDIIGPVDYGSDQGDVFLGQQLMQSSHI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
SEDTSRKIEEEVRKLIEKGKEDARQVMTEFRKEWEAIATGLLEFETLTGEEIAGLLKGTP
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PSRPDISDDDAGPASAVPVIGKRKKPKDDGIGDAEPNPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA