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The map label for this gene is yngJ [H]

Identifier: 114797258

GI number: 114797258

Start: 3444241

End: 3445401

Strand: Reverse

Name: yngJ [H]

Synonym: HNE_3282

Alternate gene names: 114797258

Gene position: 3445401-3444241 (Counterclockwise)

Preceding gene: 114799570

Following gene: 114798845

Centisome position: 92.99

GC content: 64.51

Gene sequence:

>1161_bases
ATGACCAGTTTTGCCGCAGAACCTGAGCACGTAACAGAGATCCGCCGCCAGCTTGCCCGCTGGGTGGCCGAGAAGATGCC
GCGCGAGAAGCGACGGGAGTGGGACCGGGAGGCGACCTGGGACCGGACCCTCTTTCGCGAGATTGCGGAGATGGGGCTGA
TCGGCCTCACCATCCCCGAAGAATATGGCGGGCAGGGGGAGGATATCTACGCCGCCGCTGCCGTGATCGAGGAGCTCTGC
CAGGGCGGGCCGAGCATGGCCGGGCCGTTCATCCATGCCGCCTTCTATGGCGGGCTCAACATTTCCGAGAACGGATCGAA
AGCGCAGAAAGAGGAATTGCTGCCAAAGCTCGCGCGCGGCGAGCTGTTCCTCGCTTATGGCCTGTCGGAGCCCAATGTTG
GCGGCGACCTGCCGAGTGTTGGGACGCGGGTGGAGCGTCAGGGAAACGAGATTGTCATCAACGGCGCCAAGCGCTGGTGC
ACCGGGGCGGACTGGGCCGATTACATCTATTGCCTCTGCCGCTCGGGCGAGCCGGGTGCGCGGCATGGCAATCTCACTTT
CGTCCTTGTGCCAACCAATGCCAAGGGCGTCAGCATGCAGGCCATCGAGCACGCGAACCTGCGCTACACTCATTCGATGG
ATGTTTATCTCGATGAGGTTCGCCTGCCCGAGAGCGCCATCGTCGGCGGGCCGGAGAAGTGGAACAAGGGGTGGGATGCG
CTGGCCGGCCGCGCGCTGGACGTTGAGAAGATCGAGATCACAGCGGTCGCCTTCGGCCTTGCGCGGGCTGCGCTGGAGGA
GGCCTGGCGCTATGCCGGGGAACGCGAGCAGTTCGGCAAGCGCATCGGCCAGCATCAGGCGATTGCCCACAAGCTGGTGA
CCGCGCGCACGAAACTCGCCGCCTGCCGCCATATGCTTTACCACGCCGCCTGGCTGGCCAGCACCGGCCAGCCCTGCTCG
GCAGAGACGGCGATGGCCAAGCTCTATGTGGCCGATACGGGCGTCGAGATCGGTCTTGCCTGCCAGCAGGTGATCGGCGC
CTATGGCCTCTCGGACGCCTATGACATCGAGCGGAACCTGCGCGATCTTCTGGGTATGCCGATCGTGGGCGGATCATCGG
ACATGCAGAAGAACAACCTTGCCCGGATGTGGCGGCTCTGA

Upstream 100 bases:

>100_bases
GCAGCCATGCCCATCTCCTGTTCGGTAACTGGATCAACCAGACGTACCAGTCGACACCGTTCAGCCTTGACGAAATCGGG
CAATAGACCAGAACTGAGGC

Downstream 100 bases:

>100_bases
TGGACGCGCCCGCCGCGCCGGAGCTTTCCTATGCCGCGTATTTCAACGACCCTCTGAAACGGGCGCTGGTGCGCGCCGTT
GAGCGGGCAACGGGACAGCC

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTSFAAEPEHVTEIRRQLARWVAEKMPREKRREWDREATWDRTLFREIAEMGLIGLTIPEEYGGQGEDIYAAAAVIEELC
QGGPSMAGPFIHAAFYGGLNISENGSKAQKEELLPKLARGELFLAYGLSEPNVGGDLPSVGTRVERQGNEIVINGAKRWC
TGADWADYIYCLCRSGEPGARHGNLTFVLVPTNAKGVSMQAIEHANLRYTHSMDVYLDEVRLPESAIVGGPEKWNKGWDA
LAGRALDVEKIEITAVAFGLARAALEEAWRYAGEREQFGKRIGQHQAIAHKLVTARTKLAACRHMLYHAAWLASTGQPCS
AETAMAKLYVADTGVEIGLACQQVIGAYGLSDAYDIERNLRDLLGMPIVGGSSDMQKNNLARMWRL

Sequences:

>Translated_386_residues
MTSFAAEPEHVTEIRRQLARWVAEKMPREKRREWDREATWDRTLFREIAEMGLIGLTIPEEYGGQGEDIYAAAAVIEELC
QGGPSMAGPFIHAAFYGGLNISENGSKAQKEELLPKLARGELFLAYGLSEPNVGGDLPSVGTRVERQGNEIVINGAKRWC
TGADWADYIYCLCRSGEPGARHGNLTFVLVPTNAKGVSMQAIEHANLRYTHSMDVYLDEVRLPESAIVGGPEKWNKGWDA
LAGRALDVEKIEITAVAFGLARAALEEAWRYAGEREQFGKRIGQHQAIAHKLVTARTKLAACRHMLYHAAWLASTGQPCS
AETAMAKLYVADTGVEIGLACQQVIGAYGLSDAYDIERNLRDLLGMPIVGGSSDMQKNNLARMWRL
>Mature_385_residues
TSFAAEPEHVTEIRRQLARWVAEKMPREKRREWDREATWDRTLFREIAEMGLIGLTIPEEYGGQGEDIYAAAAVIEELCQ
GGPSMAGPFIHAAFYGGLNISENGSKAQKEELLPKLARGELFLAYGLSEPNVGGDLPSVGTRVERQGNEIVINGAKRWCT
GADWADYIYCLCRSGEPGARHGNLTFVLVPTNAKGVSMQAIEHANLRYTHSMDVYLDEVRLPESAIVGGPEKWNKGWDAL
AGRALDVEKIEITAVAFGLARAALEEAWRYAGEREQFGKRIGQHQAIAHKLVTARTKLAACRHMLYHAAWLASTGQPCSA
ETAMAKLYVADTGVEIGLACQQVIGAYGLSDAYDIERNLRDLLGMPIVGGSSDMQKNNLARMWRL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=27.2251308900524, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=26.7195767195767, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4557231, Length=353, Percent_Identity=28.8951841359773, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI187960098, Length=353, Percent_Identity=28.8951841359773, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI226958414, Length=360, Percent_Identity=27.7777777777778, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4501859, Length=351, Percent_Identity=29.0598290598291, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=28.5333333333333, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7656849, Length=354, Percent_Identity=26.5536723163842, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=27.1468144044321, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI76496475, Length=358, Percent_Identity=27.0949720670391, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4557235, Length=358, Percent_Identity=27.0949720670391, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4503943, Length=357, Percent_Identity=24.9299719887955, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7669494, Length=359, Percent_Identity=24.7910863509749, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38505218, Length=349, Percent_Identity=25.7879656160458, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1786223, Length=351, Percent_Identity=29.9145299145299, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI87081958, Length=361, Percent_Identity=29.3628808864266, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87081702, Length=340, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=29.4277929155313, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17508101, Length=354, Percent_Identity=30.5084745762712, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=30.8108108108108, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=370, Percent_Identity=28.3783783783784, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=28.2122905027933, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71990804, Length=300, Percent_Identity=30.6666666666667, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=27.7333333333333, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=26.7379679144385, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=24.8, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=383, Percent_Identity=26.6318537859008, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=30.8016877637131, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=28.673835125448, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=365, Percent_Identity=26.5753424657534, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=27.027027027027, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=24.21875, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=23.0452674897119, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=30.2702702702703, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24666513, Length=353, Percent_Identity=30.3116147308782, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356377, Length=348, Percent_Identity=30.4597701149425, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21355753, Length=339, Percent_Identity=28.9085545722714, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24660351, Length=388, Percent_Identity=28.0927835051546, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI19920834, Length=371, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281363737, Length=352, Percent_Identity=24.7159090909091, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42537; Mature: 42406

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFAAEPEHVTEIRRQLARWVAEKMPREKRREWDREATWDRTLFREIAEMGLIGLTIPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCH
EYGGQGEDIYAAAAVIEELCQGGPSMAGPFIHAAFYGGLNISENGSKAQKEELLPKLARG
HHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
ELFLAYGLSEPNVGGDLPSVGTRVERQGNEIVINGAKRWCTGADWADYIYCLCRSGEPGA
CEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHCCCCCCC
RHGNLTFVLVPTNAKGVSMQAIEHANLRYTHSMDVYLDEVRLPESAIVGGPEKWNKGWDA
CCCCEEEEEEECCCCCCCHHHHHCCCCEEEECHHHHHHHHCCCHHHHCCCHHHHCCCHHH
LAGRALDVEKIEITAVAFGLARAALEEAWRYAGEREQFGKRIGQHQAIAHKLVTARTKLA
HCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ACRHMLYHAAWLASTGQPCSAETAMAKLYVADTGVEIGLACQQVIGAYGLSDAYDIERNL
HHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHH
RDLLGMPIVGGSSDMQKNNLARMWRL
HHHHCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TSFAAEPEHVTEIRRQLARWVAEKMPREKRREWDREATWDRTLFREIAEMGLIGLTIPE
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCH
EYGGQGEDIYAAAAVIEELCQGGPSMAGPFIHAAFYGGLNISENGSKAQKEELLPKLARG
HHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
ELFLAYGLSEPNVGGDLPSVGTRVERQGNEIVINGAKRWCTGADWADYIYCLCRSGEPGA
CEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHCCCCCCC
RHGNLTFVLVPTNAKGVSMQAIEHANLRYTHSMDVYLDEVRLPESAIVGGPEKWNKGWDA
CCCCEEEEEEECCCCCCCHHHHHCCCCEEEECHHHHHHHHCCCHHHHCCCHHHHCCCHHH
LAGRALDVEKIEITAVAFGLARAALEEAWRYAGEREQFGKRIGQHQAIAHKLVTARTKLA
HCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ACRHMLYHAAWLASTGQPCSAETAMAKLYVADTGVEIGLACQQVIGAYGLSDAYDIERNL
HHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHH
RDLLGMPIVGGSSDMQKNNLARMWRL
HHHHCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]