Click here to switch to the map view.

The map label for this gene is dsbE [H]

Identifier: 114331623

GI number: 114331623

Start: 1721913

End: 1722437

Strand: Reverse

Name: dsbE [H]

Synonym: Neut_1637

Alternate gene names: 114331623

Gene position: 1722437-1721913 (Counterclockwise)

Preceding gene: 114331624

Following gene: 114331622

Centisome position: 64.73

GC content: 41.71

Gene sequence:

>525_bases
ATGATGCGTTTCCTGCTGCCTCTCGCGATATTTGTAATATTAGTAATCTTTCTAGGAATTGGTTTGACCTTGAATCCGCG
TCAAGTGCCATCTCCATTAATAGATAAACCCGCACCCATTTTTCATCTGCAACAACTCTATGATTCCAGTAAGACGCTTT
CGTCTGAGGATAATCTTGGAAAAGTATGGATGTTGAATGTTTGGGCTTCCTGGTGTGTGGCTTGTCGTGATGAGCACCCT
GTGCTGGTAGAACTCTCAAAGCTGGGTATTGTTCCAATTTATGGTCTGAATTACAAAGATCAGCGTGATACTGCCATGCA
GTGGCTTAGACAATATGGTAACCCTTATGAAACCAGTATCGTTGATGCGGATGGGAAAGTCGGTATTGATTATGGCGTTT
ATGGCGTGCCAGAAACTTATGTAATCGATAAGCAAGGCATTATCAGGTATAAGCATATTGGCCCGGTAACGGTTGAATCA
CTGAAAGATAAAATTCTTCCTTTAATCAAGGAACTGAAGAGTTGA

Upstream 100 bases:

>100_bases
ATCGCCGCAAAGCAGCTGAAACACCTGGTGCTGCAGATATACCTGCCAAAGATATTATGGTGACCAATTCTGTTACTCTT
TCGGAGGAAGGTGGTAAAGC

Downstream 100 bases:

>100_bases
GTTGGTAATGATGAAACAACTGATCTGTATGAGAGTGGACTCGTTAAAGCGTTGCTTAATGGTGATTATTCTGTCTCTTA
TAGCTTTCCAGGGCTATGCA

Product: periplasmic protein thiol--disulphide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MMRFLLPLAIFVILVIFLGIGLTLNPRQVPSPLIDKPAPIFHLQQLYDSSKTLSSEDNLGKVWMLNVWASWCVACRDEHP
VLVELSKLGIVPIYGLNYKDQRDTAMQWLRQYGNPYETSIVDADGKVGIDYGVYGVPETYVIDKQGIIRYKHIGPVTVES
LKDKILPLIKELKS

Sequences:

>Translated_174_residues
MMRFLLPLAIFVILVIFLGIGLTLNPRQVPSPLIDKPAPIFHLQQLYDSSKTLSSEDNLGKVWMLNVWASWCVACRDEHP
VLVELSKLGIVPIYGLNYKDQRDTAMQWLRQYGNPYETSIVDADGKVGIDYGVYGVPETYVIDKQGIIRYKHIGPVTVES
LKDKILPLIKELKS
>Mature_174_residues
MMRFLLPLAIFVILVIFLGIGLTLNPRQVPSPLIDKPAPIFHLQQLYDSSKTLSSEDNLGKVWMLNVWASWCVACRDEHP
VLVELSKLGIVPIYGLNYKDQRDTAMQWLRQYGNPYETSIVDADGKVGIDYGVYGVPETYVIDKQGIIRYKHIGPVTVES
LKDKILPLIKELKS

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=172, Percent_Identity=44.7674418604651, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19715; Mature: 19715

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRFLLPLAIFVILVIFLGIGLTLNPRQVPSPLIDKPAPIFHLQQLYDSSKTLSSEDNLG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KVWMLNVWASWCVACRDEHPVLVELSKLGIVPIYGLNYKDQRDTAMQWLRQYGNPYETSI
CEEHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEE
VDADGKVGIDYGVYGVPETYVIDKQGIIRYKHIGPVTVESLKDKILPLIKELKS
ECCCCCEECCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRFLLPLAIFVILVIFLGIGLTLNPRQVPSPLIDKPAPIFHLQQLYDSSKTLSSEDNLG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KVWMLNVWASWCVACRDEHPVLVELSKLGIVPIYGLNYKDQRDTAMQWLRQYGNPYETSI
CEEHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEE
VDADGKVGIDYGVYGVPETYVIDKQGIIRYKHIGPVTVESLKDKILPLIKELKS
ECCCCCEECCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA