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The map label for this gene is exbB [H]

Identifier: 114331602

GI number: 114331602

Start: 1698495

End: 1699292

Strand: Direct

Name: exbB [H]

Synonym: Neut_1616

Alternate gene names: 114331602

Gene position: 1698495-1699292 (Clockwise)

Preceding gene: 114331601

Following gene: 114331603

Centisome position: 63.83

GC content: 49.5

Gene sequence:

>798_bases
ATGGAAAAAACACTGGGGTTCTCTAATTTTCTGACACAGGTTGACTCTGTTGGAATGAGTGTGCTGATACTTCTACTTAC
CTTGTCAGTCGCAAGCTGGTACCTGATTGTGACCAAAAGTATCAGCAATATGATTGCCTCTCGTCGCGCAAAAGATTTTC
TCAAGCATTTCTGGCATATTGATTCTGTGCCCCAGCTTAAAACAGAGATCAGTGCGATGACTGATAGACATGCGTTTGTT
CAGCTGGCTAAAACAGCATTGACTGCCACTGCAGATTCACAAAAGCACGGACTGGAGAAACTGGCAGCAGCTGGTGGTAC
AAACGAGCTGCTCACCCGTTCGCTGCGCAATAGTCTGGATCAGGAAGCGGCCCGTATTGAATATGGTCTCACCATCATTG
CTTCAGCAGGCTCTTCTGCACCCTATATTGGATTGTTCGGCACAGTCTGGGGGATTTATCATGCCCTGATCCAGATTGGC
CTGTCTGGTCAGGGTACGCTGGATAAAGTGGCTGGTCCGGTGGGCGAAGCATTGATCATGACAGCCCTGGGCCTGGCGGT
TGCCATACCTGCTGTACTGGCCTACAACGCCTTCATACGACGCAACCGCCTGTGGATGGCCCAACTGGATGACTTCGCTC
ATGATCTCTACACCATCATGACAACAGGCAGCAAGTCCAGCGAAGAAAATAATCAAAAAACACCTCAAAAAGAAGCATCA
ACCATCTCACAGCATACCCGGGTAACAGAACCGACCAATCCATCAGCAGACGTTATCAGCGGAGAGGGGCACCACTAA

Upstream 100 bases:

>100_bases
TGTCAAAACCTGGCGTTGCCGGCCAGCAATGCGTGGTGGACAAGCAGTACCAGCAATTGCCCTGCAGCCTTTTAATTTTG
TCATCGAAGGAAGTTAATAG

Downstream 100 bases:

>100_bases
TGGCTTTCGGTGATTCAACCCGTTATCAGAGCAAGACGGCCATGACTGAAATCAACGTGGTACCGCTAGTGGATGTAATG
CTGGTATTGCTGATTATTTT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MEKTLGFSNFLTQVDSVGMSVLILLLTLSVASWYLIVTKSISNMIASRRAKDFLKHFWHIDSVPQLKTEISAMTDRHAFV
QLAKTALTATADSQKHGLEKLAAAGGTNELLTRSLRNSLDQEAARIEYGLTIIASAGSSAPYIGLFGTVWGIYHALIQIG
LSGQGTLDKVAGPVGEALIMTALGLAVAIPAVLAYNAFIRRNRLWMAQLDDFAHDLYTIMTTGSKSSEENNQKTPQKEAS
TISQHTRVTEPTNPSADVISGEGHH

Sequences:

>Translated_265_residues
MEKTLGFSNFLTQVDSVGMSVLILLLTLSVASWYLIVTKSISNMIASRRAKDFLKHFWHIDSVPQLKTEISAMTDRHAFV
QLAKTALTATADSQKHGLEKLAAAGGTNELLTRSLRNSLDQEAARIEYGLTIIASAGSSAPYIGLFGTVWGIYHALIQIG
LSGQGTLDKVAGPVGEALIMTALGLAVAIPAVLAYNAFIRRNRLWMAQLDDFAHDLYTIMTTGSKSSEENNQKTPQKEAS
TISQHTRVTEPTNPSADVISGEGHH
>Mature_265_residues
MEKTLGFSNFLTQVDSVGMSVLILLLTLSVASWYLIVTKSISNMIASRRAKDFLKHFWHIDSVPQLKTEISAMTDRHAFV
QLAKTALTATADSQKHGLEKLAAAGGTNELLTRSLRNSLDQEAARIEYGLTIIASAGSSAPYIGLFGTVWGIYHALIQIG
LSGQGTLDKVAGPVGEALIMTALGLAVAIPAVLAYNAFIRRNRLWMAQLDDFAHDLYTIMTTGSKSSEENNQKTPQKEAS
TISQHTRVTEPTNPSADVISGEGHH

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=220, Percent_Identity=31.8181818181818, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789381, Length=217, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 28668; Mature: 28668

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTLGFSNFLTQVDSVGMSVLILLLTLSVASWYLIVTKSISNMIASRRAKDFLKHFWHI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSVPQLKTEISAMTDRHAFVQLAKTALTATADSQKHGLEKLAAAGGTNELLTRSLRNSLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QEAARIEYGLTIIASAGSSAPYIGLFGTVWGIYHALIQIGLSGQGTLDKVAGPVGEALIM
HHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TALGLAVAIPAVLAYNAFIRRNRLWMAQLDDFAHDLYTIMTTGSKSSEENNQKTPQKEAS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
TISQHTRVTEPTNPSADVISGEGHH
HHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKTLGFSNFLTQVDSVGMSVLILLLTLSVASWYLIVTKSISNMIASRRAKDFLKHFWHI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSVPQLKTEISAMTDRHAFVQLAKTALTATADSQKHGLEKLAAAGGTNELLTRSLRNSLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QEAARIEYGLTIIASAGSSAPYIGLFGTVWGIYHALIQIGLSGQGTLDKVAGPVGEALIM
HHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TALGLAVAIPAVLAYNAFIRRNRLWMAQLDDFAHDLYTIMTTGSKSSEENNQKTPQKEAS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
TISQHTRVTEPTNPSADVISGEGHH
HHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]