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The map label for this gene is fixN [H]

Identifier: 114331569

GI number: 114331569

Start: 1663224

End: 1664882

Strand: Direct

Name: fixN [H]

Synonym: Neut_1582

Alternate gene names: 114331569

Gene position: 1663224-1664882 (Clockwise)

Preceding gene: 114331568

Following gene: 114331570

Centisome position: 62.5

GC content: 49.91

Gene sequence:

>1659_bases
ATGGATAGTGCATTACTGAGCTTGCTGGCAGCCTTTTTATTATCACTCATTGGTTTGCTTGTATTCATCTGGTCGCTGCG
TAAAGGATTGCTGTTTGAAAACCCACGAGCGGCCGCCACAATTTTTGCACCTGGAGAAATTGGCAAAGCAGATGATCCAG
CTCTGGATGATCAGGCTGCAAAACGCCTTCAAGAGGCGATAACCGCTTCCCACGGCAGTGAGCCGCAAGCCGAAGACCCG
GATGAGATCAAGGATCGCATCGCTGCTGACCGTTCATCTGCCTTCCCGGTCTTTATGTTCATTTCCTTTGGCTGTATGTG
GCTGATACTGGGCGCGACAGCTGGTCTCATTTCATCACTGAAATTACACTGGCCAGACTTTCTGGTATCCGAGGCTTGGA
TGACCTTTGGGCGCATGCGAACAGTACACCTGATCGCAGTACTTTATGGCTGGATCACCAACGTTGGACTGGGCATTATC
ATCTGGCTGCTGCCACGCTTGTTGCGCACACCACTGAAAGGACCAATGTGGGTCATGCTGGGGGGGACATTTATCAACAT
CGGAATTGCCAGCTCCATTGGCGCAATCGGTTCCGGCTGGAGCGATGGTATGGAATACCTGGAAATCCCATGGCAGATCG
GCTTGTTCATTCAGGCAGGTATGGTTTGTATCATTGGTTCGGTATTTTATACATTGTTCCACCGCAAAGCACATGAACTC
TATGTAAGCGTGTGGTATCACATCGCTGCCTTATTATGGATTTCGCTGCTGTTTACCGTCGGAAAACTTCCGGGTGTTCA
TTTTGGCGTACAACAGGCGATGACCAACTGGTGGTATGGGCACAACGTTCTAGGCCTCTGGTTTACTCCGATCGCCTTGG
GCGCCATCTACTATTTTCTACCCAAAACAATCGGGCGGCGAGTGCGTTCCTATAATCTTTCATTGTTGGGTTTCTGGACA
CTGGCGTTTTTCTACGCACAGGTGGGCGGGCACCATCTAGTTGGCGGGCCGGTACCTGGATGGCTGATTACGCTATCCAT
CGTGCAGAGTATGATGATGATCATCCCCGTAGTTGCATTCTCAGTCAATATGGCAGGAACCATGTGGGGGAGAATGCGTC
TGGCACTTTATTCGCCAACGCTACGATTCATGATGTTTGGCGGCTTTATGTATCTGCTGTCATCGGTGCAAGGGTCATTT
GAGGCCTTACGCAGCATTCAACAAGTTGCGCACTTTACACACTTCACAGTAGCTCATGCTCACCTTGGCGCCTACGGTTT
CGTCTCAATGGTACTCTTCGGTGCGATCTACTTTATGATGCCGCGTGTACTACATTGGGAATGGCCCTACCCAAAACTAA
TTTCGCTGCATTTTTGGCTAGCCAGCATCGGTATCCTAATCTATTTCGTTTTCCTGTCTTGGGGCGGCTGGCTACAGGGC
CTTGCAATGCTCGATACCACACGTGAATTTATGGATTCAGTACGACTAACTATTCCGTACCTGGAATGGCGCAGTGTAGG
AGGTGGGCTGATGTGGCTTAGCCATGTGATTTTTGTCGGACATTTACTGGTCATGATACTGCGATTCGGCCCCAATCGTA
CCGGGGAAGCACTGTTTGCACCGGAGAAAATGAAACTGGAGATGATGCATGGAAAATGA

Upstream 100 bases:

>100_bases
TAGGCTGCAAATCCCTCAGCAAGCAGCTATCGTGTCGAGGACAAGCAAGTTAATACAGTGTTGCTAGTTAAACTGCAACA
CAATCAAGAGAGAGTGCAAT

Downstream 100 bases:

>100_bases
AGCTAAGCTGACTGCTGGCGCAATAACGACTTTTGGAATTGCCGTCGCAGCACTGGTGGTGCTTCCATATATCCAGGTGC
GTGATATTCAGCCGCCTGAA

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome CBB3 subunit 1; Cytochrome c oxidase polypeptide I homolog; Heme B/copper cytochrome c oxidase subunit [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDSALLSLLAAFLLSLIGLLVFIWSLRKGLLFENPRAAATIFAPGEIGKADDPALDDQAAKRLQEAITASHGSEPQAEDP
DEIKDRIAADRSSAFPVFMFISFGCMWLILGATAGLISSLKLHWPDFLVSEAWMTFGRMRTVHLIAVLYGWITNVGLGII
IWLLPRLLRTPLKGPMWVMLGGTFINIGIASSIGAIGSGWSDGMEYLEIPWQIGLFIQAGMVCIIGSVFYTLFHRKAHEL
YVSVWYHIAALLWISLLFTVGKLPGVHFGVQQAMTNWWYGHNVLGLWFTPIALGAIYYFLPKTIGRRVRSYNLSLLGFWT
LAFFYAQVGGHHLVGGPVPGWLITLSIVQSMMMIIPVVAFSVNMAGTMWGRMRLALYSPTLRFMMFGGFMYLLSSVQGSF
EALRSIQQVAHFTHFTVAHAHLGAYGFVSMVLFGAIYFMMPRVLHWEWPYPKLISLHFWLASIGILIYFVFLSWGGWLQG
LAMLDTTREFMDSVRLTIPYLEWRSVGGGLMWLSHVIFVGHLLVMILRFGPNRTGEALFAPEKMKLEMMHGK

Sequences:

>Translated_552_residues
MDSALLSLLAAFLLSLIGLLVFIWSLRKGLLFENPRAAATIFAPGEIGKADDPALDDQAAKRLQEAITASHGSEPQAEDP
DEIKDRIAADRSSAFPVFMFISFGCMWLILGATAGLISSLKLHWPDFLVSEAWMTFGRMRTVHLIAVLYGWITNVGLGII
IWLLPRLLRTPLKGPMWVMLGGTFINIGIASSIGAIGSGWSDGMEYLEIPWQIGLFIQAGMVCIIGSVFYTLFHRKAHEL
YVSVWYHIAALLWISLLFTVGKLPGVHFGVQQAMTNWWYGHNVLGLWFTPIALGAIYYFLPKTIGRRVRSYNLSLLGFWT
LAFFYAQVGGHHLVGGPVPGWLITLSIVQSMMMIIPVVAFSVNMAGTMWGRMRLALYSPTLRFMMFGGFMYLLSSVQGSF
EALRSIQQVAHFTHFTVAHAHLGAYGFVSMVLFGAIYFMMPRVLHWEWPYPKLISLHFWLASIGILIYFVFLSWGGWLQG
LAMLDTTREFMDSVRLTIPYLEWRSVGGGLMWLSHVIFVGHLLVMILRFGPNRTGEALFAPEKMKLEMMHGK
>Mature_552_residues
MDSALLSLLAAFLLSLIGLLVFIWSLRKGLLFENPRAAATIFAPGEIGKADDPALDDQAAKRLQEAITASHGSEPQAEDP
DEIKDRIAADRSSAFPVFMFISFGCMWLILGATAGLISSLKLHWPDFLVSEAWMTFGRMRTVHLIAVLYGWITNVGLGII
IWLLPRLLRTPLKGPMWVMLGGTFINIGIASSIGAIGSGWSDGMEYLEIPWQIGLFIQAGMVCIIGSVFYTLFHRKAHEL
YVSVWYHIAALLWISLLFTVGKLPGVHFGVQQAMTNWWYGHNVLGLWFTPIALGAIYYFLPKTIGRRVRSYNLSLLGFWT
LAFFYAQVGGHHLVGGPVPGWLITLSIVQSMMMIIPVVAFSVNMAGTMWGRMRLALYSPTLRFMMFGGFMYLLSSVQGSF
EALRSIQQVAHFTHFTVAHAHLGAYGFVSMVLFGAIYFMMPRVLHWEWPYPKLISLHFWLASIGILIYFVFLSWGGWLQG
LAMLDTTREFMDSVRLTIPYLEWRSVGGGLMWLSHVIFVGHLLVMILRFGPNRTGEALFAPEKMKLEMMHGK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61949; Mature: 61949

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSALLSLLAAFLLSLIGLLVFIWSLRKGLLFENPRAAATIFAPGEIGKADDPALDDQAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHH
KRLQEAITASHGSEPQAEDPDEIKDRIAADRSSAFPVFMFISFGCMWLILGATAGLISSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLHWPDFLVSEAWMTFGRMRTVHLIAVLYGWITNVGLGIIIWLLPRLLRTPLKGPMWVML
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GGTFINIGIASSIGAIGSGWSDGMEYLEIPWQIGLFIQAGMVCIIGSVFYTLFHRKAHEL
CCEEEEEEHHHHHCCCCCCHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSVWYHIAALLWISLLFTVGKLPGVHFGVQQAMTNWWYGHNVLGLWFTPIALGAIYYFL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
PKTIGRRVRSYNLSLLGFWTLAFFYAQVGGHHLVGGPVPGWLITLSIVQSMMMIIPVVAF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SVNMAGTMWGRMRLALYSPTLRFMMFGGFMYLLSSVQGSFEALRSIQQVAHFTHFTVAHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGAYGFVSMVLFGAIYFMMPRVLHWEWPYPKLISLHFWLASIGILIYFVFLSWGGWLQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LAMLDTTREFMDSVRLTIPYLEWRSVGGGLMWLSHVIFVGHLLVMILRFGPNRTGEALFA
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
PEKMKLEMMHGK
CCHHHHEECCCC
>Mature Secondary Structure
MDSALLSLLAAFLLSLIGLLVFIWSLRKGLLFENPRAAATIFAPGEIGKADDPALDDQAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHH
KRLQEAITASHGSEPQAEDPDEIKDRIAADRSSAFPVFMFISFGCMWLILGATAGLISSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLHWPDFLVSEAWMTFGRMRTVHLIAVLYGWITNVGLGIIIWLLPRLLRTPLKGPMWVML
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GGTFINIGIASSIGAIGSGWSDGMEYLEIPWQIGLFIQAGMVCIIGSVFYTLFHRKAHEL
CCEEEEEEHHHHHCCCCCCHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSVWYHIAALLWISLLFTVGKLPGVHFGVQQAMTNWWYGHNVLGLWFTPIALGAIYYFL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
PKTIGRRVRSYNLSLLGFWTLAFFYAQVGGHHLVGGPVPGWLITLSIVQSMMMIIPVVAF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SVNMAGTMWGRMRLALYSPTLRFMMFGGFMYLLSSVQGSFEALRSIQQVAHFTHFTVAHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGAYGFVSMVLFGAIYFMMPRVLHWEWPYPKLISLHFWLASIGILIYFVFLSWGGWLQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LAMLDTTREFMDSVRLTIPYLEWRSVGGGLMWLSHVIFVGHLLVMILRFGPNRTGEALFA
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
PEKMKLEMMHGK
CCHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8386371; 12597275 [H]