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The map label for this gene is pheA [H]

Identifier: 114331557

GI number: 114331557

Start: 1645736

End: 1646794

Strand: Reverse

Name: pheA [H]

Synonym: Neut_1570

Alternate gene names: 114331557

Gene position: 1646794-1645736 (Counterclockwise)

Preceding gene: 114331558

Following gene: 114331556

Centisome position: 61.88

GC content: 49.67

Gene sequence:

>1059_bases
ATGACGGAACAGCTTACACAACTGCGCAATGAAATCGATGCAATCGACGATGAATTGCTCCGATTGATTAATACCCGTGC
ACGGCTTGCGCAACAGATTGGTCGACAGAAATCCGGCACGGCTTATCGCCCTGAGCGTGAGTCACAAATCTTTTCTCGTT
TGCAGCAAGCAAATTCGGGGCCATTACGAGATGAGCATATCGTGCATTTGTTTACCGAAGTCATATCAATCTGTCGTGCA
CTGGAAGAGCCTTTAGTTGTTGCTTATCTTGGGCCACAGGGTACATTCTCGGAAGAAGCAGTGACCAAACGTTTTGGCAG
CGCGGTTACCTCAATACCCTGCAGTTCAATTGACGATATTTTTCGCAAGGTTGAATCCGGTGCAGCTAATTACGGTGTTG
TACCAGTCGAAAATTCGACTGAGGGGGCAGTCGGCAGAACAATGGACTTGTTGTTACTGACGCCCTTGAAGATATGTGGC
GAACTTCAGCTGCCCATCCATCAGTGCCTGATGGCACAGCACGCCGATCTGGCTTCTATTCGAAGAGTTTATTCACATCC
GCAATCATTTGCACAATGTCAGGCATGGCTCAATGAAAATCTGACTGCCGCTGATCGTATCAATGCTGCCAGCAATGCAG
ATGCTGCCCGTCAGGTTGCAGCAGATAGCAGCGCCGCTGCGATTGCCGGGAAGAAAGCTGCTGAAGTATTCGGACTGAAG
ATCTGTGCCACCAATATCGAGGATAGTCCGAATAATACGACACGATTTCTGGTGGTAGGTATGCAGGAAGTGGCGCCCTC
CGGAAAAGATAAAACCTCACTGGCCATGGCCACGCATAATCGACCTGGTTCAGTCCATGAGCTTCTGGCGCCCTTTGCAC
AACATTGTGTCAGTATGACGCGTCTGGAATCGCGCCCTTCACGCGCCAGTCTGTGGGAATATGTTTTCTTTACGGATATT
GAAGGGCATCAGGAAGATGAAAACGTAGCCAGGGCACTTCAGATGCTGCGCGACAATGCAACCTTTCTGAAGGTTTTCGG
CTCTTATCCTGCAGCGTAA

Upstream 100 bases:

>100_bases
GGGTGTGTTAATGGTTCGTTATCTGCCTGTTTCAGTACCTTCCGAGCCTGAACGAGTGTAAAGCAGAAAATCCAGCCGCA
ATCTTATTAAATCCCTATTG

Downstream 100 bases:

>100_bases
ATTAATTAATTCCTGAATGTTATGAACCTTTTTGAACTGGCACCGGAATATATCCGGGCAATCCAACCCTATCAGCCGGG
TAAACCGATATCGGAACTGG

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTEQLTQLRNEIDAIDDELLRLINTRARLAQQIGRQKSGTAYRPERESQIFSRLQQANSGPLRDEHIVHLFTEVISICRA
LEEPLVVAYLGPQGTFSEEAVTKRFGSAVTSIPCSSIDDIFRKVESGAANYGVVPVENSTEGAVGRTMDLLLLTPLKICG
ELQLPIHQCLMAQHADLASIRRVYSHPQSFAQCQAWLNENLTAADRINAASNADAARQVAADSSAAAIAGKKAAEVFGLK
ICATNIEDSPNNTTRFLVVGMQEVAPSGKDKTSLAMATHNRPGSVHELLAPFAQHCVSMTRLESRPSRASLWEYVFFTDI
EGHQEDENVARALQMLRDNATFLKVFGSYPAA

Sequences:

>Translated_352_residues
MTEQLTQLRNEIDAIDDELLRLINTRARLAQQIGRQKSGTAYRPERESQIFSRLQQANSGPLRDEHIVHLFTEVISICRA
LEEPLVVAYLGPQGTFSEEAVTKRFGSAVTSIPCSSIDDIFRKVESGAANYGVVPVENSTEGAVGRTMDLLLLTPLKICG
ELQLPIHQCLMAQHADLASIRRVYSHPQSFAQCQAWLNENLTAADRINAASNADAARQVAADSSAAAIAGKKAAEVFGLK
ICATNIEDSPNNTTRFLVVGMQEVAPSGKDKTSLAMATHNRPGSVHELLAPFAQHCVSMTRLESRPSRASLWEYVFFTDI
EGHQEDENVARALQMLRDNATFLKVFGSYPAA
>Mature_351_residues
TEQLTQLRNEIDAIDDELLRLINTRARLAQQIGRQKSGTAYRPERESQIFSRLQQANSGPLRDEHIVHLFTEVISICRAL
EEPLVVAYLGPQGTFSEEAVTKRFGSAVTSIPCSSIDDIFRKVESGAANYGVVPVENSTEGAVGRTMDLLLLTPLKICGE
LQLPIHQCLMAQHADLASIRRVYSHPQSFAQCQAWLNENLTAADRINAASNADAARQVAADSSAAAIAGKKAAEVFGLKI
CATNIEDSPNNTTRFLVVGMQEVAPSGKDKTSLAMATHNRPGSVHELLAPFAQHCVSMTRLESRPSRASLWEYVFFTDIE
GHQEDENVARALQMLRDNATFLKVFGSYPAA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=375, Percent_Identity=33.0666666666667, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324013, Length=323, Percent_Identity=28.7925696594427, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 38581; Mature: 38450

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQLTQLRNEIDAIDDELLRLINTRARLAQQIGRQKSGTAYRPERESQIFSRLQQANSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
PLRDEHIVHLFTEVISICRALEEPLVVAYLGPQGTFSEEAVTKRFGSAVTSIPCSSIDDI
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
FRKVESGAANYGVVPVENSTEGAVGRTMDLLLLTPLKICGELQLPIHQCLMAQHADLASI
HHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
RRVYSHPQSFAQCQAWLNENLTAADRINAASNADAARQVAADSSAAAIAGKKAAEVFGLK
HHHHHCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ICATNIEDSPNNTTRFLVVGMQEVAPSGKDKTSLAMATHNRPGSVHELLAPFAQHCVSMT
EEECCCCCCCCCCEEEEEEEHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
RLESRPSRASLWEYVFFTDIEGHQEDENVARALQMLRDNATFLKVFGSYPAA
HHHCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TEQLTQLRNEIDAIDDELLRLINTRARLAQQIGRQKSGTAYRPERESQIFSRLQQANSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
PLRDEHIVHLFTEVISICRALEEPLVVAYLGPQGTFSEEAVTKRFGSAVTSIPCSSIDDI
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
FRKVESGAANYGVVPVENSTEGAVGRTMDLLLLTPLKICGELQLPIHQCLMAQHADLASI
HHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
RRVYSHPQSFAQCQAWLNENLTAADRINAASNADAARQVAADSSAAAIAGKKAAEVFGLK
HHHHHCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ICATNIEDSPNNTTRFLVVGMQEVAPSGKDKTSLAMATHNRPGSVHELLAPFAQHCVSMT
EEECCCCCCCCCCEEEEEEEHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
RLESRPSRASLWEYVFFTDIEGHQEDENVARALQMLRDNATFLKVFGSYPAA
HHHCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]