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The map label for this gene is murA

Identifier: 114331543

GI number: 114331543

Start: 1628284

End: 1629537

Strand: Reverse

Name: murA

Synonym: Neut_1556

Alternate gene names: 114331543

Gene position: 1629537-1628284 (Counterclockwise)

Preceding gene: 114331546

Following gene: 114331541

Centisome position: 61.24

GC content: 52.39

Gene sequence:

>1254_bases
ATGCAGAAACTTGTCATTCACGGGGGGTCGAAGCTCCATGGTGAAATCAGTATTTCCGGTGCCAAAAACGCAGCTTTGCC
CGTATTATGCGCATCGCTACTGACTGCTGAACCATTTGCCATACAGAATATCCCGCATCTCAGGGATGTCACTACTATGC
TGGCATTGCTTGAACAGATTGGTGTGCGCATTCTAACAAATGAACCAGGCACTACAGAACTGTCTGCGGCCAATATTACC
AATCCAACCGCTTCCTACGACATGGTGAAAACCATGCGTGCCGCCATCCTCGTATTGGGTCCATTACTGGCGCGAACCGG
ACAGGCACATATTTCCTTGCCGGGTGGTTGCGCAATCGGCATGCGGCCGGTCGATCAGCATATCAAGGGACTGCAAGCCA
TGGGGGCGGAAATCAATATTGAGCAAGGCTATATCCTTGCTCAGGTGGGCCGCCTTTCAGGTGCACGTATCGCCATGGAC
GTTGTCACCGTTACCGGAACTGAAAACCTGATGATGGCCGCCACACTTGCTTCCGGCACGACCATTCTGGAAAATGCCGC
CCGTGAACCTGAAGTGATTGATCTGGCAAATTGTCTCATCGGTATGGGAGCAAAAATAGAAGGAGCAGGCAATGACATTA
TCATTATCGAAGGGGTAGATCGTTTGCATGGTGGTTCACACGTCGTCATGCCTGATCGCATTGAAACCGGGACGTTCTTG
ACCGCAGTCGCTGCCTGTGGTGGTGACGTCACCCTGATCGGAACACGCGCAGATACACTTGACGTTGTACTGGGCAAGCT
GGCAGAAGCTGGAGCAGACATTGATATAGGCGGGGATTGGATCCGATTGTGCATGCAGCAGCGGCCGCAACCGGTCAGTC
TGCGCACTGCGCCCTATCCGGCCTTTCCTACCGACATGCAAGCACAATTCATGGCGTTAAACAGCATTGCCGGCGGCACC
TCCATCATGACAGAAACAATTTTTGAAAATCGCTTCATGCATGTACAGGAGCTCACACGCCTGAACGCAGATATTCAGGT
TGAGGGTAATACTGCGATCGTGCATGGCATTCCCCAGCTTGATGGTGCCAGTGTGATGGCAACCGATCTGCGCGCCTCCG
CCTGCCTCATCATCGCCGGATTGATTGCGCAAGGCGAAACCATCGTTGACCGGATCTATCATCTGGATCGCGGCTATGAA
CAAATCGAACAAAAACTGGCGCAAGTGGGTGCACACATCAAACGCATAAATTAG

Upstream 100 bases:

>100_bases
CAAATTTGCTCATTCTGACTCCTCAGTTAGTACGATAAAATGCAAAGGATTACGCCCATGTGGGTGCAACAATATTTTAA
TTCTTGTTAAGAGTAGATTC

Downstream 100 bases:

>100_bases
AGCATCACAGAAAGATTGCCATGCAAACTGATCCCTGTATTGGACATTGCTCGCAACTTCATCCAATCAGTTCTACCGTG
GGTGAGGTGGCAGTTACACG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQIGVRILTNEPGTTELSAANIT
NPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIGMRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMD
VVTVTGTENLMMAATLASGTTILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFL
TAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYPAFPTDMQAQFMALNSIAGGT
SIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQLDGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYE
QIEQKLAQVGAHIKRIN

Sequences:

>Translated_417_residues
MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQIGVRILTNEPGTTELSAANIT
NPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIGMRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMD
VVTVTGTENLMMAATLASGTTILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFL
TAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYPAFPTDMQAQFMALNSIAGGT
SIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQLDGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYE
QIEQKLAQVGAHIKRIN
>Mature_417_residues
MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQIGVRILTNEPGTTELSAANIT
NPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIGMRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMD
VVTVTGTENLMMAATLASGTTILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFL
TAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYPAFPTDMQAQFMALNSIAGGT
SIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQLDGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYE
QIEQKLAQVGAHIKRIN

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=58.7112171837709, Blast_Score=496, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_NITEC (Q0AFT2)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747765.1
- ProteinModelPortal:   Q0AFT2
- SMR:   Q0AFT2
- STRING:   Q0AFT2
- GeneID:   4272449
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1556
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q0AFT2
- ProtClustDB:   PRK09369
- BioCyc:   NEUT335283:NEUT_1556-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44096; Mature: 44096

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQI
CCEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHC
GVRILTNEPGTTELSAANITNPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIG
CEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEC
MRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMDVVTVTGTENLMMAATLASGT
CCCHHHHHHHHHHCCCEEEECCCEEEEEHHCCCCCEEEEEEEEEECCCCEEEEEECCCCC
TILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFL
HHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCEEEEECCHHHCCCCEEEECCCCCCCHHH
TAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYP
HHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCC
AFPTDMQAQFMALNSIAGGTSIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCC
DGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYEQIEQKLAQVGAHIKRIN
CCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQI
CCEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHC
GVRILTNEPGTTELSAANITNPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIG
CEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEC
MRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMDVVTVTGTENLMMAATLASGT
CCCHHHHHHHHHHCCCEEEECCCEEEEEHHCCCCCEEEEEEEEEECCCCEEEEEECCCCC
TILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFL
HHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCEEEEECCHHHCCCCEEEECCCCCCCHHH
TAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYP
HHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCC
AFPTDMQAQFMALNSIAGGTSIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCC
DGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYEQIEQKLAQVGAHIKRIN
CCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA