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The map label for this gene is 114331540

Identifier: 114331540

GI number: 114331540

Start: 1623957

End: 1624697

Strand: Direct

Name: 114331540

Synonym: Neut_1553

Alternate gene names: NA

Gene position: 1623957-1624697 (Clockwise)

Preceding gene: 114331537

Following gene: 114331542

Centisome position: 61.03

GC content: 45.88

Gene sequence:

>741_bases
ATGGCTATAAACATATTCAAACAACAAGTTGATTCCATTATTCAAAGCAAGCATCTGTTGCAACATCCGTTCTACATCGC
CTGGACCGAAGGCAAGCTGACCCGCGAGCAGCTGCGCCACTACGCTGAGCAATATTTTTATAATGTATTGGCTGAACCCA
CCTACCTCAGCGCAGTTCACTTCAACACCCCACATTTTCACAACGAAGAAAACTGTGGTGATATCAGCGTGCGTCAAGAG
GTCCTCAAAAACCTGATCGATGAAGAACACGGAGAAAAAAATCACCCTGCCCTGTGGAAAGCATTTGCCTTTGCATTAGG
CGCGAATGATGCCAGCCTGGCAAAAGCCGATGCATTGCCGGAAACAGAAAATCTGGTTTCAACCTTTCGCGACATCTGCA
TAAACGAATCTTTTTATGCAGGATTGGCCGCATTACATGCATTTGAATCCCAGGTACCTGATATTGCCGCTGTCAAGATC
GACGGCCTGGCCAAATTCTATGACATGAAAAATCCGGAGGATTATGAGTTCTTCTCGGTACACCAGACAGCTGATATTTT
CCATTCACAAGCAGAATGGGCAATCATTGAAAGATTTGCTGATACTCCGGAAAAACAGGCCGAAGTACTGGCCGCCACAC
GCCGCGCTTGTGATGCTCTGTGGAAATTCCTGGATGGTATTCACGAAAATTACTGTGCCAATCTCATCTGCGAGGAAAAA
GCAGTAGTTACGTTGCATTAA

Upstream 100 bases:

>100_bases
AAAACGACAGAATTCTCTGGCATAAAATTGACTTCATTTACTGAATTGGCGATGATTAGCGGCGCATCACATTTCATTCC
ACTCTGAACAGGAGCTTTTC

Downstream 100 bases:

>100_bases
TCCCATATTGGCCTGATTACAACAGTTTACGCCGGGCAATCATCCCCAGTTTAAGGGGGATTGCCCGATTTCTTGAGTCC
CTTATTTTTCCCGCTTTGCT

Product: TENA/THI-4 domain-containing protein

Products: NA

Alternate protein names: Chlamydia protein associating with death domains; CADD [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAINIFKQQVDSIIQSKHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVHFNTPHFHNEENCGDISVRQE
VLKNLIDEEHGEKNHPALWKAFAFALGANDASLAKADALPETENLVSTFRDICINESFYAGLAALHAFESQVPDIAAVKI
DGLAKFYDMKNPEDYEFFSVHQTADIFHSQAEWAIIERFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEK
AVVTLH

Sequences:

>Translated_246_residues
MAINIFKQQVDSIIQSKHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVHFNTPHFHNEENCGDISVRQE
VLKNLIDEEHGEKNHPALWKAFAFALGANDASLAKADALPETENLVSTFRDICINESFYAGLAALHAFESQVPDIAAVKI
DGLAKFYDMKNPEDYEFFSVHQTADIFHSQAEWAIIERFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEK
AVVTLH
>Mature_245_residues
AINIFKQQVDSIIQSKHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVHFNTPHFHNEENCGDISVRQEV
LKNLIDEEHGEKNHPALWKAFAFALGANDASLAKADALPETENLVSTFRDICINESFYAGLAALHAFESQVPDIAAVKID
GLAKFYDMKNPEDYEFFSVHQTADIFHSQAEWAIIERFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEKA
VVTLH

Specific function: Chlamydia specific toxin inducing apoptosis in mammalian cell lines [H]

COG id: COG5424

COG function: function code H; Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C

Gene ontology:

Cell location: Secreted. Note=Secreted into the host cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pqqC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: NA

Molecular weight: Translated: 28090; Mature: 27959

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINIFKQQVDSIIQSKHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVH
CCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
FNTPHFHNEENCGDISVRQEVLKNLIDEEHGEKNHPALWKAFAFALGANDASLAKADALP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCC
ETENLVSTFRDICINESFYAGLAALHAFESQVPDIAAVKIDGLAKFYDMKNPEDYEFFSV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHEEH
HQTADIFHSQAEWAIIERFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AVVTLH
EEEEEC
>Mature Secondary Structure 
AINIFKQQVDSIIQSKHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVH
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
FNTPHFHNEENCGDISVRQEVLKNLIDEEHGEKNHPALWKAFAFALGANDASLAKADALP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCC
ETENLVSTFRDICINESFYAGLAALHAFESQVPDIAAVKIDGLAKFYDMKNPEDYEFFSV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHEEH
HQTADIFHSQAEWAIIERFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AVVTLH
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]