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The map label for this gene is nrdR

Identifier: 114331538

GI number: 114331538

Start: 1621954

End: 1622436

Strand: Reverse

Name: nrdR

Synonym: Neut_1551

Alternate gene names: 114331538

Gene position: 1622436-1621954 (Counterclockwise)

Preceding gene: 114331539

Following gene: 114331535

Centisome position: 60.97

GC content: 51.76

Gene sequence:

>483_bases
ATGCGATGCCCGTTCTGCGGTGCTGAAGATACCAGCGTAGTCGATTCGCGTGTCAGCGAAGAAGGTTCCAGGATCAGACG
CAGGCGACAATGTACGGCCTGCGGAAAGCGCTTCACAACGTATGAAACAGTTGAGGTGCGTTTTCCACAGATTATCAAGC
AGGGCGGTAATCGCGTTGAGTTCAACCGGGAAAAGCTCTACACCAGTTTTGCCCGGGCGTTACACAAGCGCCCGGTTCCG
GTTGGGCAGGTAGATGCCGCAATAGAACGTATTCTGCAGAAACTATTGGGAGGCGGGGCACAAGAAATTTCATCGCGCAC
AATTGGTGAATGGGTCATGCAAGAGCTGTACAAGCTGGATAAGGTAGCCTACATCCGCTTTGCTTCTGTGTATAGAAGTT
TTGAAGATGTAGGAGATTTTCAGGAGGTAATCCGGGAGGTTCAAGCCTCTCCATCAAGCCTGGACGATGAGCCACCAGGC
TAA

Upstream 100 bases:

>100_bases
AAATTTCCGGTGTATGGAAATTGATTATTTTGTCTTGTGCACCAGGTTTCTGTGTCGGCTATCCGGTTCCAGTTACCTGT
AATTTTGGAGGTACAGAGCA

Downstream 100 bases:

>100_bases
CAAATGACCAAGAGAGATTATTATGATCAATCATCAAATGAATTACATCTCTGGAAGCCGTTTGCGCAAAAGTTTGCATC
TGATGATGGGCGTGCCGGAG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRCPFCGAEDTSVVDSRVSEEGSRIRRRRQCTACGKRFTTYETVEVRFPQIIKQGGNRVEFNREKLYTSFARALHKRPVP
VGQVDAAIERILQKLLGGGAQEISSRTIGEWVMQELYKLDKVAYIRFASVYRSFEDVGDFQEVIREVQASPSSLDDEPPG

Sequences:

>Translated_160_residues
MRCPFCGAEDTSVVDSRVSEEGSRIRRRRQCTACGKRFTTYETVEVRFPQIIKQGGNRVEFNREKLYTSFARALHKRPVP
VGQVDAAIERILQKLLGGGAQEISSRTIGEWVMQELYKLDKVAYIRFASVYRSFEDVGDFQEVIREVQASPSSLDDEPPG
>Mature_160_residues
MRCPFCGAEDTSVVDSRVSEEGSRIRRRRQCTACGKRFTTYETVEVRFPQIIKQGGNRVEFNREKLYTSFARALHKRPVP
VGQVDAAIERILQKLLGGGAQEISSRTIGEWVMQELYKLDKVAYIRFASVYRSFEDVGDFQEVIREVQASPSSLDDEPPG

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=54.1666666666667, Blast_Score=160, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_NITEC (Q0AFT7)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747760.1
- STRING:   Q0AFT7
- GeneID:   4273632
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1551
- NMPDR:   fig|335283.3.peg.1834
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q0AFT7
- ProtClustDB:   PRK00464
- BioCyc:   NEUT335283:NEUT_1551-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18196; Mature: 18196

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGAEDTSVVDSRVSEEGSRIRRRRQCTACGKRFTTYETVEVRFPQIIKQGGNRVE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
FNREKLYTSFARALHKRPVPVGQVDAAIERILQKLLGGGAQEISSRTIGEWVMQELYKLD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVGDFQEVIREVQASPSSLDDEPPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRCPFCGAEDTSVVDSRVSEEGSRIRRRRQCTACGKRFTTYETVEVRFPQIIKQGGNRVE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
FNREKLYTSFARALHKRPVPVGQVDAAIERILQKLLGGGAQEISSRTIGEWVMQELYKLD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVGDFQEVIREVQASPSSLDDEPPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA