Click here to switch to the map view.

The map label for this gene is neuA [H]

Identifier: 114331535

GI number: 114331535

Start: 1616897

End: 1617613

Strand: Reverse

Name: neuA [H]

Synonym: Neut_1548

Alternate gene names: 114331535

Gene position: 1617613-1616897 (Counterclockwise)

Preceding gene: 114331538

Following gene: 114331534

Centisome position: 60.79

GC content: 49.65

Gene sequence:

>717_bases
ATGTTAATTTATTCCCTCATCCCCGCGCGAGGCGGGTCAAAAGCTGTTCCGCATAAAAATATCCGGTTTTTATGTGGCAA
GCCGCTGATTGCCCATTCAATTGAAGTTTCGCTCAGATCACCTTCTATTCAGAGAACTTTTGTCAGCACCGATTCGAAGA
AGATTGCAGAAATTGCAAGAAATGCCGGAGCGGAGGTTCCTTTTTTGAGACCGGTTGATCTGGCACAGGATGATACGCGG
GATCTGCCGGTATTCCTGCATTTTTTGAGCTGGCTGGAGCAGCGCCATGTGCCTCTTCCTGATGCCATTTTCCAGTTTCG
GCCCACTTCTCCTGCGCGCAGGGTTGAAAAAATAGAGGAAGCGGTCGGACTGCTGAAAAAACATCCAGATGCTGATTCCG
TCCGTGGAGTGACCGAACCGGCGCAGAATCCTTACAAGATGTGGACCATCGGTAATGATGGTTTTATGCAGGCTCTGCTG
AGTATTCCTGGTGTCCCGGAGCCTTTTAACGAACCAAGGCAGCGCTTACCCGAGGTTTACTGGCAGGTCGGTTATCTGGA
TCTGATACGTACCCGGACGATTCTGGAGAAGCAATCACTCACAGGTGCCCACATACTGCCATTGAAGATCGAAAGCGGGG
ATTCGATCGATATCGATGATGAATTCTCGTTCCAGCTCGCTGAATTTCTAATGGAAAAACGGGGGATCATCCGTTGA

Upstream 100 bases:

>100_bases
GCTGGTAGCCGGTTTGTAAAATACCAACTTGTGAATCATCAGAATTTGACTTCACCCATTTATTTGTTTATTTGATACCT
GATTTGATAAATTTCAGCCA

Downstream 100 bases:

>100_bases
AGGCTCTGGTAGTCGGACTGGGCTCCATCGGAGTCAGGCATCTCAATAATCTGCATGCACTCGGGGTTCGGGAATTGGGC
GCAGTGCGTACTCGCAATCT

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLIYSLIPARGGSKAVPHKNIRFLCGKPLIAHSIEVSLRSPSIQRTFVSTDSKKIAEIARNAGAEVPFLRPVDLAQDDTR
DLPVFLHFLSWLEQRHVPLPDAIFQFRPTSPARRVEKIEEAVGLLKKHPDADSVRGVTEPAQNPYKMWTIGNDGFMQALL
SIPGVPEPFNEPRQRLPEVYWQVGYLDLIRTRTILEKQSLTGAHILPLKIESGDSIDIDDEFSFQLAEFLMEKRGIIR

Sequences:

>Translated_238_residues
MLIYSLIPARGGSKAVPHKNIRFLCGKPLIAHSIEVSLRSPSIQRTFVSTDSKKIAEIARNAGAEVPFLRPVDLAQDDTR
DLPVFLHFLSWLEQRHVPLPDAIFQFRPTSPARRVEKIEEAVGLLKKHPDADSVRGVTEPAQNPYKMWTIGNDGFMQALL
SIPGVPEPFNEPRQRLPEVYWQVGYLDLIRTRTILEKQSLTGAHILPLKIESGDSIDIDDEFSFQLAEFLMEKRGIIR
>Mature_238_residues
MLIYSLIPARGGSKAVPHKNIRFLCGKPLIAHSIEVSLRSPSIQRTFVSTDSKKIAEIARNAGAEVPFLRPVDLAQDDTR
DLPVFLHFLSWLEQRHVPLPDAIFQFRPTSPARRVEKIEEAVGLLKKHPDADSVRGVTEPAQNPYKMWTIGNDGFMQALL
SIPGVPEPFNEPRQRLPEVYWQVGYLDLIRTRTILEKQSLTGAHILPLKIESGDSIDIDDEFSFQLAEFLMEKRGIIR

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=231, Percent_Identity=26.8398268398268, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26929; Mature: 26929

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYSLIPARGGSKAVPHKNIRFLCGKPLIAHSIEVSLRSPSIQRTFVSTDSKKIAEIAR
CEEEEEECCCCCCCCCCCCCCEEEECCCHHHHEEEEEECCCCCEEHHHCCCHHHHHHHHH
NAGAEVPFLRPVDLAQDDTRDLPVFLHFLSWLEQRHVPLPDAIFQFRPTSPARRVEKIEE
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHH
AVGLLKKHPDADSVRGVTEPAQNPYKMWTIGNDGFMQALLSIPGVPEPFNEPRQRLPEVY
HHHHHHCCCCCHHHCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
WQVGYLDLIRTRTILEKQSLTGAHILPLKIESGDSIDIDDEFSFQLAEFLMEKRGIIR
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLIYSLIPARGGSKAVPHKNIRFLCGKPLIAHSIEVSLRSPSIQRTFVSTDSKKIAEIAR
CEEEEEECCCCCCCCCCCCCCEEEECCCHHHHEEEEEECCCCCEEHHHCCCHHHHHHHHH
NAGAEVPFLRPVDLAQDDTRDLPVFLHFLSWLEQRHVPLPDAIFQFRPTSPARRVEKIEE
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHH
AVGLLKKHPDADSVRGVTEPAQNPYKMWTIGNDGFMQALLSIPGVPEPFNEPRQRLPEVY
HHHHHHCCCCCHHHCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
WQVGYLDLIRTRTILEKQSLTGAHILPLKIESGDSIDIDDEFSFQLAEFLMEKRGIIR
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1398032; 7830552; 8113198; 8045888; 10710307 [H]