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The map label for this gene is htpX [H]

Identifier: 114331522

GI number: 114331522

Start: 1605179

End: 1606057

Strand: Direct

Name: htpX [H]

Synonym: Neut_1535

Alternate gene names: 114331522

Gene position: 1605179-1606057 (Clockwise)

Preceding gene: 114331518

Following gene: 114331527

Centisome position: 60.32

GC content: 48.58

Gene sequence:

>879_bases
ATGAAACGGATTTTTCTTTTTATTGTAACGAACTTGGCCATACTGGTAATGCTGAGTATAACCCTGCGTTTGCTCGGTGT
TGACCGCATACTGGATGCTGAAGGCAGTGGATTAAATTTTAATGCTCTACTGGTTTTATCGGCTGTAATAGGATTTGGCG
GTTCGCTCATTTCGCTTGCCATGTCCAAATGGAGTGCCAAGCACATGACTGGTGCCACGGTCATTGAAATTCCTTCAAAT
TCCACCGAAGGTTGGCTGGTAGAAACTGTCCGCCGGCAGGCCAAAGCAGCTGGCGTGGGTATGCCTGAAGTGGCCATTTA
CGATTCACCCGATATTAATGCATTCGCAACAGGAATGAATAGAAACAATGCGTTGGTAGCAGTCAGCTCAGGATTGCTGC
AAAAAATGAGTCGTGATGAGGCTGAAGCGGTACTGGCTCATGAAGTCAGTCATATTGCCAATGGCGACATGGTAACGCTG
GCATTGATTCAGGGCGTGGTGAATACATTTGTGATTTTCCTCTCCCGTATCATCGGCCATGTAATTGATCGCGCTGTCTT
CAGAACGGAAGAAGGACATGGCCCCGCCTATTTCGTTACCAGCCTTGTCGCACAACTGGTACTGGGCATACTCGCCACGA
TAATTGTGATGTGGTTCAGTCGTCAGCGTGAATTCCGCGCAGATGCCGGGAGTGCACAGCTTTCCGGAAGAAATAAAATG
GTTGCCGCACTGCGGCGATTGCAACAGGAATATGAGCCATCTCATTTGCCAGATAAGATCGCTGCTTTTGGAATCTCTGG
ACAAAAGAGCCAGATTGGGCGTCTGTTTATGTCACACCCCCCTCTGGAAGAGCGCATCCAGGCATTACAATCTGCCTGA

Upstream 100 bases:

>100_bases
TTGTGAAATATGTCACCATATATCGGTTTGCTTTGAACGATTGTTTTTTATTACATTCAAAATCAGACACGTGTACTAAT
AAACCTGAAGGAAGAGGATA

Downstream 100 bases:

>100_bases
TGATAGAGCAGCCGGGGCTGGTGAATCCTTACACCAGCCCCGGCAAAAATGTAAATAACCATCTTATTGAATCAATCATC
AATGATTATTTCCTCGTCAT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKRIFLFIVTNLAILVMLSITLRLLGVDRILDAEGSGLNFNALLVLSAVIGFGGSLISLAMSKWSAKHMTGATVIEIPSN
STEGWLVETVRRQAKAAGVGMPEVAIYDSPDINAFATGMNRNNALVAVSSGLLQKMSRDEAEAVLAHEVSHIANGDMVTL
ALIQGVVNTFVIFLSRIIGHVIDRAVFRTEEGHGPAYFVTSLVAQLVLGILATIIVMWFSRQREFRADAGSAQLSGRNKM
VAALRRLQQEYEPSHLPDKIAAFGISGQKSQIGRLFMSHPPLEERIQALQSA

Sequences:

>Translated_292_residues
MKRIFLFIVTNLAILVMLSITLRLLGVDRILDAEGSGLNFNALLVLSAVIGFGGSLISLAMSKWSAKHMTGATVIEIPSN
STEGWLVETVRRQAKAAGVGMPEVAIYDSPDINAFATGMNRNNALVAVSSGLLQKMSRDEAEAVLAHEVSHIANGDMVTL
ALIQGVVNTFVIFLSRIIGHVIDRAVFRTEEGHGPAYFVTSLVAQLVLGILATIIVMWFSRQREFRADAGSAQLSGRNKM
VAALRRLQQEYEPSHLPDKIAAFGISGQKSQIGRLFMSHPPLEERIQALQSA
>Mature_292_residues
MKRIFLFIVTNLAILVMLSITLRLLGVDRILDAEGSGLNFNALLVLSAVIGFGGSLISLAMSKWSAKHMTGATVIEIPSN
STEGWLVETVRRQAKAAGVGMPEVAIYDSPDINAFATGMNRNNALVAVSSGLLQKMSRDEAEAVLAHEVSHIANGDMVTL
ALIQGVVNTFVIFLSRIIGHVIDRAVFRTEEGHGPAYFVTSLVAQLVLGILATIIVMWFSRQREFRADAGSAQLSGRNKM
VAALRRLQQEYEPSHLPDKIAAFGISGQKSQIGRLFMSHPPLEERIQALQSA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=297, Percent_Identity=52.8619528619529, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31651; Mature: 31651

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLFIVTNLAILVMLSITLRLLGVDRILDAEGSGLNFNALLVLSAVIGFGGSLISLA
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWSAKHMTGATVIEIPSNSTEGWLVETVRRQAKAAGVGMPEVAIYDSPDINAFATGMN
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCC
RNNALVAVSSGLLQKMSRDEAEAVLAHEVSHIANGDMVTLALIQGVVNTFVIFLSRIIGH
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIDRAVFRTEEGHGPAYFVTSLVAQLVLGILATIIVMWFSRQREFRADAGSAQLSGRNKM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VAALRRLQQEYEPSHLPDKIAAFGISGQKSQIGRLFMSHPPLEERIQALQSA
HHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRIFLFIVTNLAILVMLSITLRLLGVDRILDAEGSGLNFNALLVLSAVIGFGGSLISLA
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWSAKHMTGATVIEIPSNSTEGWLVETVRRQAKAAGVGMPEVAIYDSPDINAFATGMN
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCC
RNNALVAVSSGLLQKMSRDEAEAVLAHEVSHIANGDMVTLALIQGVVNTFVIFLSRIIGH
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIDRAVFRTEEGHGPAYFVTSLVAQLVLGILATIIVMWFSRQREFRADAGSAQLSGRNKM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VAALRRLQQEYEPSHLPDKIAAFGISGQKSQIGRLFMSHPPLEERIQALQSA
HHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]