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The map label for this gene is pqqL [C]

Identifier: 114331517

GI number: 114331517

Start: 1599693

End: 1601084

Strand: Direct

Name: pqqL [C]

Synonym: Neut_1530

Alternate gene names: 114331517

Gene position: 1599693-1601084 (Clockwise)

Preceding gene: 114331513

Following gene: 114331518

Centisome position: 60.11

GC content: 48.49

Gene sequence:

>1392_bases
ATGAAAATCAGTTTTTGCCCCAGTCGTCTCATTATTTTTCTTTGCGTTACATTATTGGTATCGCCACTACCAGCTTCAGC
CAATCCACACGAATATCTGCTTGATAATGGCCTTAAACTGGTTATCAAGGAAGATCATCGTTCGCCAGTGGTCATTCAGC
AGGTCTGGTACAAGGCCGGCAGTATGGATGAAGTCAACGGGACAACCGGCGTGGCACATGCACTGGAACACATGATGTTC
AAGGGAACTGACAGTGTGCCTACCGGAGAATTTTCCAGAAGAATTGCAGCCGTTGGCGGTAAGGAAAATGCTTTTACCAG
TAGTGACTACACTGCTTATTATCAGCAGCTGCACCAGCGCCACTTGCCAATGGCAATGGAACTTGAATCCGACCGCATGC
ACAATCTGCGGCTGACACAAGAAGAATTTGCCAAGGAAATACAGGTTGTAATGGAAGAAAGAAGGCTGCGCACGGATGAT
CAGGCACACGCGTTACTGTACGAAAAACTAATGGCGACAGCCTTTCAGGCACATCCCTATCGTCGCCCTATTATTGGCTG
GATGAATGATCTGGAGCATATGCAGGTAAGTGATGCCCAGGATTGGTATAAGCGCTGGTATGCGCCCAATAATGCGGTAC
TGGTAGTGGTAGGTGACGTTGATCCGGAAAGCGTACTCGCACTGGCAAAAAAATATTACGGAAGATTCAGCGCCGGTAAA
ATTCCATCTCTGTCCGAACGCAAGCCACAAATTGAACCGCCTCAAATAGGAATCAAGCGACTGGTAGTAAAGGCACCTGC
AAAACTCCCGCATCTGATCATGGGATACAAAGTTCCTGTACTCAAAGATCCCAAAAATGACTGGGAGCCCTACGCACTGA
CCATTCTGGCTGAAGTACTGGATGGCAACGCCGCAGCAAGACTTAACAAAGCCCTGGTACGTGAAACACGCGTTGCCATC
TCGGCTGATGCCGGCTATAGCGCTATTGAGCGTGGCCCTGGTACTTTTTATATTGATGGGACTCCCAGTGAAGGCAGAAC
AGCAGATGAACTGGAACAGTCGATTCGTACTGAAATTGACAAAATTATACAGTCCGGAATCACCCAGGAAGAACTTGCTC
GCGTCAAGGCACAAGTAGTGGCAAGCCGTACTTATCAACTTGACTCCACTTTTGCGCAGGCGATGCAGATTGGCAGACTG
GAAAGCATCGGACTGTCCCACCGAGATGCAGATATCATTCTGGAACGACTACAGGCAGTTACGGCAGAGCAGGTCAGGAA
TGTCGCTGAGAAATATCTGATAGATGATTCGCTGACTGTGGCCGTACTGGATCCGCAGCCTTTATCGGAAACCTCTTCCT
CCCGGAACAGCAACATTGAACTAAAACACTAA

Upstream 100 bases:

>100_bases
TAGGCTGTTTCTGTTTCGGGGAAACAAACATCATACCATCAACCAATTGCCGAGGTAATGTCAGTCATCCGCCCCAGGCC
AGTTCAACTTTCAGCACAAT

Downstream 100 bases:

>100_bases
CCTTGCCTATCTTCTCGAAAGACAAAGGAAAGGTAGCTGTGCTAGCAGTTGCTCATTACTATTTCCAGGGCGGCACCATC
TGTAAACTGTTGATTCTTTT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKISFCPSRLIIFLCVTLLVSPLPASANPHEYLLDNGLKLVIKEDHRSPVVIQQVWYKAGSMDEVNGTTGVAHALEHMMF
KGTDSVPTGEFSRRIAAVGGKENAFTSSDYTAYYQQLHQRHLPMAMELESDRMHNLRLTQEEFAKEIQVVMEERRLRTDD
QAHALLYEKLMATAFQAHPYRRPIIGWMNDLEHMQVSDAQDWYKRWYAPNNAVLVVVGDVDPESVLALAKKYYGRFSAGK
IPSLSERKPQIEPPQIGIKRLVVKAPAKLPHLIMGYKVPVLKDPKNDWEPYALTILAEVLDGNAAARLNKALVRETRVAI
SADAGYSAIERGPGTFYIDGTPSEGRTADELEQSIRTEIDKIIQSGITQEELARVKAQVVASRTYQLDSTFAQAMQIGRL
ESIGLSHRDADIILERLQAVTAEQVRNVAEKYLIDDSLTVAVLDPQPLSETSSSRNSNIELKH

Sequences:

>Translated_463_residues
MKISFCPSRLIIFLCVTLLVSPLPASANPHEYLLDNGLKLVIKEDHRSPVVIQQVWYKAGSMDEVNGTTGVAHALEHMMF
KGTDSVPTGEFSRRIAAVGGKENAFTSSDYTAYYQQLHQRHLPMAMELESDRMHNLRLTQEEFAKEIQVVMEERRLRTDD
QAHALLYEKLMATAFQAHPYRRPIIGWMNDLEHMQVSDAQDWYKRWYAPNNAVLVVVGDVDPESVLALAKKYYGRFSAGK
IPSLSERKPQIEPPQIGIKRLVVKAPAKLPHLIMGYKVPVLKDPKNDWEPYALTILAEVLDGNAAARLNKALVRETRVAI
SADAGYSAIERGPGTFYIDGTPSEGRTADELEQSIRTEIDKIIQSGITQEELARVKAQVVASRTYQLDSTFAQAMQIGRL
ESIGLSHRDADIILERLQAVTAEQVRNVAEKYLIDDSLTVAVLDPQPLSETSSSRNSNIELKH
>Mature_463_residues
MKISFCPSRLIIFLCVTLLVSPLPASANPHEYLLDNGLKLVIKEDHRSPVVIQQVWYKAGSMDEVNGTTGVAHALEHMMF
KGTDSVPTGEFSRRIAAVGGKENAFTSSDYTAYYQQLHQRHLPMAMELESDRMHNLRLTQEEFAKEIQVVMEERRLRTDD
QAHALLYEKLMATAFQAHPYRRPIIGWMNDLEHMQVSDAQDWYKRWYAPNNAVLVVVGDVDPESVLALAKKYYGRFSAGK
IPSLSERKPQIEPPQIGIKRLVVKAPAKLPHLIMGYKVPVLKDPKNDWEPYALTILAEVLDGNAAARLNKALVRETRVAI
SADAGYSAIERGPGTFYIDGTPSEGRTADELEQSIRTEIDKIIQSGITQEELARVKAQVVASRTYQLDSTFAQAMQIGRL
ESIGLSHRDADIILERLQAVTAEQVRNVAEKYLIDDSLTVAVLDPQPLSETSSSRNSNIELKH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=426, Percent_Identity=26.056338028169, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI46593007, Length=217, Percent_Identity=29.4930875576037, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1787770, Length=232, Percent_Identity=30.6034482758621, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71999683, Length=428, Percent_Identity=23.3644859813084, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17553678, Length=246, Percent_Identity=27.2357723577236, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=378, Percent_Identity=24.6031746031746, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323421, Length=322, Percent_Identity=23.2919254658385, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357875, Length=420, Percent_Identity=25.2380952380952, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646943, Length=420, Percent_Identity=25.2380952380952, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51932; Mature: 51932

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISFCPSRLIIFLCVTLLVSPLPASANPHEYLLDNGLKLVIKEDHRSPVVIQQVWYKAG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCC
SMDEVNGTTGVAHALEHMMFKGTDSVPTGEFSRRIAAVGGKENAFTSSDYTAYYQQLHQR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HLPMAMELESDRMHNLRLTQEEFAKEIQVVMEERRLRTDDQAHALLYEKLMATAFQAHPY
CCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
RRPIIGWMNDLEHMQVSDAQDWYKRWYAPNNAVLVVVGDVDPESVLALAKKYYGRFSAGK
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
IPSLSERKPQIEPPQIGIKRLVVKAPAKLPHLIMGYKVPVLKDPKNDWEPYALTILAEVL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEECCCCCCCHHHHHHHHHHH
DGNAAARLNKALVRETRVAISADAGYSAIERGPGTFYIDGTPSEGRTADELEQSIRTEID
CCCHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
KIIQSGITQEELARVKAQVVASRTYQLDSTFAQAMQIGRLESIGLSHRDADIILERLQAV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHH
TAEQVRNVAEKYLIDDSLTVAVLDPQPLSETSSSRNSNIELKH
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MKISFCPSRLIIFLCVTLLVSPLPASANPHEYLLDNGLKLVIKEDHRSPVVIQQVWYKAG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCC
SMDEVNGTTGVAHALEHMMFKGTDSVPTGEFSRRIAAVGGKENAFTSSDYTAYYQQLHQR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HLPMAMELESDRMHNLRLTQEEFAKEIQVVMEERRLRTDDQAHALLYEKLMATAFQAHPY
CCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
RRPIIGWMNDLEHMQVSDAQDWYKRWYAPNNAVLVVVGDVDPESVLALAKKYYGRFSAGK
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
IPSLSERKPQIEPPQIGIKRLVVKAPAKLPHLIMGYKVPVLKDPKNDWEPYALTILAEVL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEECCCCCCCHHHHHHHHHHH
DGNAAARLNKALVRETRVAISADAGYSAIERGPGTFYIDGTPSEGRTADELEQSIRTEID
CCCHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
KIIQSGITQEELARVKAQVVASRTYQLDSTFAQAMQIGRLESIGLSHRDADIILERLQAV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHH
TAEQVRNVAEKYLIDDSLTVAVLDPQPLSETSSSRNSNIELKH
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]