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The map label for this gene is folE2 [H]

Identifier: 114331490

GI number: 114331490

Start: 1573284

End: 1574087

Strand: Direct

Name: folE2 [H]

Synonym: Neut_1502

Alternate gene names: 114331490

Gene position: 1573284-1574087 (Clockwise)

Preceding gene: 114331489

Following gene: 114331491

Centisome position: 59.12

GC content: 44.53

Gene sequence:

>804_bases
ATGAAAAAACATACTGATCAACCTATCGCTGATGTGCAGGGCTCACCGGATACCAGACATATCGCAATTGACAGAGTCGG
AATCAAAGCGATTCGTCACCCGGTTCTGGTCGCCGATAAGGATGGTGGTTCCCAGCATACCGTGGCGCAATTTAATATGT
ACGTCAATCTGCCACATAATTTCAAAGGGACGCATATGTCCCGTTTTGTGGAGATACTAAATAGCCACGAACGTGAAATT
TCGGTTGAATCATTTGAAGAAATTTTGCGCTCCATGGTCAGCAGGCTGGAATCAGATTCCGGCCATATTGAAATGACTTT
TCCCTACTTCGTCAATAAATCAGCCCCTATCTCAGGTGTAAAAAGCTTGCTGGATTATGAGGTAACCTTTATCGGCGAAA
TTAAACATGGCGATCAATATGGGTTTACCATGAAGGTGATCGTTCCTGTTACCAGCCTGTGCCCCTGCTCCAAGAAAATA
TCCGATTACGGTGCGCATAACCAGCGTTCACACGTCACCATTTCTGTACACACTAACAGCTTCGTCTGGATTGAGGACGT
TATCAGAATTGCGGAAGAACAGGCCTCATGCGAACTGTTCGGTCTGCTGAAACGGCCGGATGAAAAATATGTCACAGAAA
AGGCCTATAACAATCCGAAATTTGTCGAAGATATCGTCCGTGATGTCGCCGAAATACTTAATCATGATGACCGGATAGAT
GCCTATGTTGTTGAATCAGAAAACTTTGAATCCATACATAATCACTCTGCATACGCACTGATAGAGCGCGACAAGCGAAA
GTAA

Upstream 100 bases:

>100_bases
CAAATCAGCAGCAAAGTTGGCGAGCTCTATTCCTTACCGGTTGCTCCAATATTTTTATACAGCTTCACAGCCAGATAATC
TGGACAGGAAGGAATTTTTT

Downstream 100 bases:

>100_bases
TAAGCCCGAGCTACTGTGCCCTCTGGTAGGCAACAGCAATTCCAGAACTACGGTGATGAATATACTTAACGTCGCAGTTT
TTTTACTTTGATAACTTTAA

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKKHTDQPIADVQGSPDTRHIAIDRVGIKAIRHPVLVADKDGGSQHTVAQFNMYVNLPHNFKGTHMSRFVEILNSHEREI
SVESFEEILRSMVSRLESDSGHIEMTFPYFVNKSAPISGVKSLLDYEVTFIGEIKHGDQYGFTMKVIVPVTSLCPCSKKI
SDYGAHNQRSHVTISVHTNSFVWIEDVIRIAEEQASCELFGLLKRPDEKYVTEKAYNNPKFVEDIVRDVAEILNHDDRID
AYVVESENFESIHNHSAYALIERDKRK

Sequences:

>Translated_267_residues
MKKHTDQPIADVQGSPDTRHIAIDRVGIKAIRHPVLVADKDGGSQHTVAQFNMYVNLPHNFKGTHMSRFVEILNSHEREI
SVESFEEILRSMVSRLESDSGHIEMTFPYFVNKSAPISGVKSLLDYEVTFIGEIKHGDQYGFTMKVIVPVTSLCPCSKKI
SDYGAHNQRSHVTISVHTNSFVWIEDVIRIAEEQASCELFGLLKRPDEKYVTEKAYNNPKFVEDIVRDVAEILNHDDRID
AYVVESENFESIHNHSAYALIERDKRK
>Mature_267_residues
MKKHTDQPIADVQGSPDTRHIAIDRVGIKAIRHPVLVADKDGGSQHTVAQFNMYVNLPHNFKGTHMSRFVEILNSHEREI
SVESFEEILRSMVSRLESDSGHIEMTFPYFVNKSAPISGVKSLLDYEVTFIGEIKHGDQYGFTMKVIVPVTSLCPCSKKI
SDYGAHNQRSHVTISVHTNSFVWIEDVIRIAEEQASCELFGLLKRPDEKYVTEKAYNNPKFVEDIVRDVAEILNHDDRID
AYVVESENFESIHNHSAYALIERDKRK

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 30455; Mature: 30455

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHTDQPIADVQGSPDTRHIAIDRVGIKAIRHPVLVADKDGGSQHTVAQFNMYVNLPHN
CCCCCCCCHHHCCCCCCCEEEEEEHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCC
FKGTHMSRFVEILNSHEREISVESFEEILRSMVSRLESDSGHIEMTFPYFVNKSAPISGV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCHHHH
KSLLDYEVTFIGEIKHGDQYGFTMKVIVPVTSLCPCSKKISDYGAHNQRSHVTISVHTNS
HHHHHCEEEEEEEECCCCCCCEEEEEEECHHHCCCCHHHHHHCCCCCCCCEEEEEEECCC
FVWIEDVIRIAEEQASCELFGLLKRPDEKYVTEKAYNNPKFVEDIVRDVAEILNHDDRID
EEEHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
AYVVESENFESIHNHSAYALIERDKRK
EEEEECCCCHHHHCCCEEEEEECCCCC
>Mature Secondary Structure
MKKHTDQPIADVQGSPDTRHIAIDRVGIKAIRHPVLVADKDGGSQHTVAQFNMYVNLPHN
CCCCCCCCHHHCCCCCCCEEEEEEHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCC
FKGTHMSRFVEILNSHEREISVESFEEILRSMVSRLESDSGHIEMTFPYFVNKSAPISGV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCHHHH
KSLLDYEVTFIGEIKHGDQYGFTMKVIVPVTSLCPCSKKISDYGAHNQRSHVTISVHTNS
HHHHHCEEEEEEEECCCCCCCEEEEEEECHHHCCCCHHHHHHCCCCCCCCEEEEEEECCC
FVWIEDVIRIAEEQASCELFGLLKRPDEKYVTEKAYNNPKFVEDIVRDVAEILNHDDRID
EEEHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
AYVVESENFESIHNHSAYALIERDKRK
EEEEECCCCHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]