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The map label for this gene is clpP2 [H]

Identifier: 114331459

GI number: 114331459

Start: 1548764

End: 1549450

Strand: Reverse

Name: clpP2 [H]

Synonym: Neut_1470

Alternate gene names: 114331459

Gene position: 1549450-1548764 (Counterclockwise)

Preceding gene: 114331460

Following gene: 114331458

Centisome position: 58.23

GC content: 51.67

Gene sequence:

>687_bases
TTGTTCAGGGCAGAATTATCTGGCGATGAAGCCACGATCTATTTGTACGACACGATTGTCAGTGATGATTTCTGGGGCGG
GGTTACCGCCATCAGTTTCGTCAAGGAACTGATGGCTATCAAAGCACCGGTCATCCACTTGCGGATCAATTCCCCCGGCG
GTGATGTGTTTTCCGCCCGCGCAATCGAAACGGCCATCCGCGAGCATAACTCCGAAGTGATTGCCCATATCGATGGTGTG
GCTGCCAGTGCTGCCTCCTACATCGCTCTGGCTGCGGACAATATCGTGATCGCCGAAGGTGCGTTTTACATGATCCACAA
AGCCTGGTCATTTGCGATGGGCAATGCGGATGATCTGCTGGAAATGGCTGCCTTGCTGGAAAAAGTGGATGAATCACTGG
TGACAACTTACGCGAAAAGAACCGGGCAGGCAGAAGATCAAATCCGAGACTGGATGAGAAATGAAACCTGGTTCAGTGCT
GCCGAGGCAGTGGAGTATGGGTTTGCTGACTCAGTCGCAGAAGATGGCCCATCTGCTAGTGCATCCATCGGTTGGGATTT
GTCAGCCTATAACGCAGCGCCAATCATTCGACAGGCACAACAATCGGCAGAGCCAGCAGAACAGGATCTACCGAAAATCG
ATACTGGTTATCTGCAGCGTATTGCTGCATTGGCCAGACATATGTAA

Upstream 100 bases:

>100_bases
ATTGAGAACATGAAGCCTATCCCAGGCGGAGATCAACTGCATACAGGAACCAATGATGGACAGAATGCTACAGCTACTGG
CGCAGAATAAATCCAAAGGT

Downstream 100 bases:

>100_bases
CGGCGCTCCCACGCCAACAAGACACCCGCCACGGGCAACCCTGGCGGGTTTTTTATTGCCACCAATCCAAAGGAACAACT
CATGGCACAAACACTGCAAG

Product: peptidase S14, ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MFRAELSGDEATIYLYDTIVSDDFWGGVTAISFVKELMAIKAPVIHLRINSPGGDVFSARAIETAIREHNSEVIAHIDGV
AASAASYIALAADNIVIAEGAFYMIHKAWSFAMGNADDLLEMAALLEKVDESLVTTYAKRTGQAEDQIRDWMRNETWFSA
AEAVEYGFADSVAEDGPSASASIGWDLSAYNAAPIIRQAQQSAEPAEQDLPKIDTGYLQRIAALARHM

Sequences:

>Translated_228_residues
MFRAELSGDEATIYLYDTIVSDDFWGGVTAISFVKELMAIKAPVIHLRINSPGGDVFSARAIETAIREHNSEVIAHIDGV
AASAASYIALAADNIVIAEGAFYMIHKAWSFAMGNADDLLEMAALLEKVDESLVTTYAKRTGQAEDQIRDWMRNETWFSA
AEAVEYGFADSVAEDGPSASASIGWDLSAYNAAPIIRQAQQSAEPAEQDLPKIDTGYLQRIAALARHM
>Mature_228_residues
MFRAELSGDEATIYLYDTIVSDDFWGGVTAISFVKELMAIKAPVIHLRINSPGGDVFSARAIETAIREHNSEVIAHIDGV
AASAASYIALAADNIVIAEGAFYMIHKAWSFAMGNADDLLEMAALLEKVDESLVTTYAKRTGQAEDQIRDWMRNETWFSA
AEAVEYGFADSVAEDGPSASASIGWDLSAYNAAPIIRQAQQSAEPAEQDLPKIDTGYLQRIAALARHM

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24766; Mature: 24766

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRAELSGDEATIYLYDTIVSDDFWGGVTAISFVKELMAIKAPVIHLRINSPGGDVFSAR
CCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
AIETAIREHNSEVIAHIDGVAASAASYIALAADNIVIAEGAFYMIHKAWSFAMGNADDLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCEEEECCHHHHHHHHHHHHCCCHHHHH
EMAALLEKVDESLVTTYAKRTGQAEDQIRDWMRNETWFSAAEAVEYGFADSVAEDGPSAS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCCC
ASIGWDLSAYNAAPIIRQAQQSAEPAEQDLPKIDTGYLQRIAALARHM
CCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFRAELSGDEATIYLYDTIVSDDFWGGVTAISFVKELMAIKAPVIHLRINSPGGDVFSAR
CCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
AIETAIREHNSEVIAHIDGVAASAASYIALAADNIVIAEGAFYMIHKAWSFAMGNADDLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCEEEECCHHHHHHHHHHHHCCCHHHHH
EMAALLEKVDESLVTTYAKRTGQAEDQIRDWMRNETWFSAAEAVEYGFADSVAEDGPSAS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCCC
ASIGWDLSAYNAAPIIRQAQQSAEPAEQDLPKIDTGYLQRIAALARHM
CCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]