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The map label for this gene is efp

Identifier: 114331295

GI number: 114331295

Start: 1366626

End: 1367183

Strand: Reverse

Name: efp

Synonym: Neut_1302

Alternate gene names: 114331295

Gene position: 1367183-1366626 (Counterclockwise)

Preceding gene: 114331296

Following gene: 114331294

Centisome position: 51.38

GC content: 42.47

Gene sequence:

>558_bases
ATGAAAACAGCTCAAGAACTTCGTGTAGGTAATGTGTTTATGCTCGGCAGAGACCCTATGGTTGTGCTGAAGACCGAATT
CACCAAATCCGGGCGTAATTCCTCGGTTGTAAAAATGAAATACAAGAATCTGCTGACAGAATCACCTGGCGAGGCAGTGT
ATAAGGCAGATGATAAATTCGATATAGTCGTGCTGGAGAAAAAAGAGGTGAGCTACTCGTATTATGCCAGCCCCATGTAT
GTATTTATGGATGCCGAGTTCAATCAATATGAAGTTGAAGAAGAAACCATGAGTGATGTACTCAGTTTTCTGGAAGATGG
CATGCCGTGCGAAGTTGTGTTTTATAATGACAAACCTATTTCAGTTGAAATGCCGAATTCTGTCGTGCGCGAAATTATTT
ACACTGAACCTGCAGTCAAAGGCGATACATCAGGCAAGGTAATGAAATCAGCCAAAATTGTTACTGGCTTCGAGTTGCCG
GTACCGTTGTTTTGTGAAATCGGTGACAAGATCGAAATTGATACTCGCACACGCGAATATCGCAGCCGTGTCAAATAA

Upstream 100 bases:

>100_bases
TGGTGAATTTTTGCAGAAACCAGTAGTTATTTCTTCATTACATTGGGGAAGTCAAAGTATAATATCCTTTTTTTTCCTTG
ACTTATATTGATTAGAATAG

Downstream 100 bases:

>100_bases
ACCCAGAATAATCAAATGTTTTTCAAGCTGCTCCGAATAATCCTGTTCTGTTCAGAGCAGCTAAAAATCAAGAAAACAAC
AATCAATTTGGATTTAAGGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKTAQELRVGNVFMLGRDPMVVLKTEFTKSGRNSSVVKMKYKNLLTESPGEAVYKADDKFDIVVLEKKEVSYSYYASPMY
VFMDAEFNQYEVEEETMSDVLSFLEDGMPCEVVFYNDKPISVEMPNSVVREIIYTEPAVKGDTSGKVMKSAKIVTGFELP
VPLFCEIGDKIEIDTRTREYRSRVK

Sequences:

>Translated_185_residues
MKTAQELRVGNVFMLGRDPMVVLKTEFTKSGRNSSVVKMKYKNLLTESPGEAVYKADDKFDIVVLEKKEVSYSYYASPMY
VFMDAEFNQYEVEEETMSDVLSFLEDGMPCEVVFYNDKPISVEMPNSVVREIIYTEPAVKGDTSGKVMKSAKIVTGFELP
VPLFCEIGDKIEIDTRTREYRSRVK
>Mature_185_residues
MKTAQELRVGNVFMLGRDPMVVLKTEFTKSGRNSSVVKMKYKNLLTESPGEAVYKADDKFDIVVLEKKEVSYSYYASPMY
VFMDAEFNQYEVEEETMSDVLSFLEDGMPCEVVFYNDKPISVEMPNSVVREIIYTEPAVKGDTSGKVMKSAKIVTGFELP
VPLFCEIGDKIEIDTRTREYRSRVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=36.0655737704918, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082061, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NITEC (Q0AGI0)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747517.1
- STRING:   Q0AGI0
- GeneID:   4272299
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1302
- NMPDR:   fig|335283.3.peg.1338
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q0AGI0
- ProtClustDB:   PRK00529
- BioCyc:   NEUT335283:NEUT_1302-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21143; Mature: 21143

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAQELRVGNVFMLGRDPMVVLKTEFTKSGRNSSVVKMKYKNLLTESPGEAVYKADDKF
CCCHHHCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHCCCCCCEEEECCCCE
DIVVLEKKEVSYSYYASPMYVFMDAEFNQYEVEEETMSDVLSFLEDGMPCEVVFYNDKPI
EEEEEECCCCCEEEECCEEEEEEECCCCEEECCHHHHHHHHHHHHCCCCEEEEEECCCEE
SVEMPNSVVREIIYTEPAVKGDTSGKVMKSAKIVTGFELPVPLFCEIGDKIEIDTRTREY
EEECCHHHHHHHHHCCCCCCCCCCCCEEECEEEEEECCCCCCEEEECCCEEEECCCHHHH
RSRVK
HHHCC
>Mature Secondary Structure
MKTAQELRVGNVFMLGRDPMVVLKTEFTKSGRNSSVVKMKYKNLLTESPGEAVYKADDKF
CCCHHHCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHCCCCCCEEEECCCCE
DIVVLEKKEVSYSYYASPMYVFMDAEFNQYEVEEETMSDVLSFLEDGMPCEVVFYNDKPI
EEEEEECCCCCEEEECCEEEEEEECCCCEEECCHHHHHHHHHHHHCCCCEEEEEECCCEE
SVEMPNSVVREIIYTEPAVKGDTSGKVMKSAKIVTGFELPVPLFCEIGDKIEIDTRTREY
EEECCHHHHHHHHHCCCCCCCCCCCCEEECEEEEEECCCCCCEEEECCCEEEECCCHHHH
RSRVK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA