Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 114331258

GI number: 114331258

Start: 1319515

End: 1320966

Strand: Reverse

Name: tldD [H]

Synonym: Neut_1263

Alternate gene names: 114331258

Gene position: 1320966-1319515 (Counterclockwise)

Preceding gene: 114331259

Following gene: 114331257

Centisome position: 49.64

GC content: 49.72

Gene sequence:

>1452_bases
ATGATGGATTCATTTGCGATAGCTGATCAGTACCTGCTGGCCCCGTATGAGTTGAATCCAACCAGGTTGCAGGATGTATT
TGGTCAGATTCTTTCCCATCGAATTGATTATGCTGACATTTATTTTCAGTATAGCCGGTCGGAGGGCTGGGTGCTGGAAG
AGGGCATCGTCAAATCAGGCAGCTTTAGCATCGACCAAGGAGTAGGGGTGCGAGCAATTAGTGGCGAGAAGACTGCTTTC
GCCTATTCGGACGATATCAGCGGTCAGGCTCTGATTTCTGCAGCTCGTGCAACACGCGCAATTGCTGCTCAAGGCAGTGA
AAAACAGACACGTATAATGGGTTTGTCAGGAAATATTACTCGACAGGCGTTGTATTATCCGTCTCTGGATCCCATCGCAC
TTTGTCAGGATGCTGACAAAATCAGGTTACTCGAACGCTTGGAAGAATTTGCGCGCGCATTGGATAAACGGGTTATTCAG
GTCATGGCATCGCTGGCAGGAGAGTACGAAGTAATCATGGTTGCACGCAGCGATGGTTTGCTCGCTGCTGATGTACGGCC
TCTGGTGAGGGTATCCTTACAGGTTATAGTCGAAGAAAGCGGTCAGCGGGAGCAGGGTGTTGCTGGAGGTGGTGGACGTT
TTGACTATGGTTATTTTACCGATACAGTGTTACAGGATTATGCGCACAAGGCTGTTCATCAGGCGATAACAAATCTGGTT
TCAAAACCGGCGCCGGCAGGAAGTATGACGGTGGTGCTAGGTAATGGGTGGCCGGGTATTTTGCTGCATGAAGCAATTGG
CCATGGTCTTGAGGCAGATTTTAACCGCAAAGGAAGTTCGGCTTTCTCCGGGCGTATCGGGGAACGAGTTGCTGCGCCGG
GAGTGACGGTGGTCGATGATGGCACGATACGTGATCGTCGCGGGTCGCTGAATATTGATGATGAAGGCAATCCGACACAA
TGCACTGTCTTAATCGAAGATGGTATTCTCAAAGGCTACCTTCAGGATAATTTAAATGCCAGGTTGATGAATCAGGCCGT
TACCGGCAACGGCCGGCGTGAATCATTTGCTCATATCCCTATGCCACGCATGACTAACACCTGCATGTTGAATGGAGACA
AAGAGCCGGAAGAGATCATTGCTTCTGTCAAACATGGTTTGTACGCCGCTAATTTTGGAGGTGGGCAGGTTGATATCACC
AGTGGCAAGTTTGTATTTTCCGCTGCGGAAGCCTACATGATTGAAAATGGTAAAATCACCTATCCGGTGAAAGGAGCTAC
TCTGATTGGCAACGGCCCTGATGTACTAACTCGCGTTTCCATGATTGGCAATGATATGGCTCTGGACCCTGGAGTCGGCA
CGTGTGGCAAGGAAGGGCAAAGTGTTCCGGTCGGTGTTGGGCAACCAACTTTGAGGGTAGATGGCTTAACAGTTGGGGGA
ACAAACGGATAG

Upstream 100 bases:

>100_bases
TATACGTTACCCTAATTTTTCTACAGGCTGCCTTCATTGCATGCCTCATAGCCACAGTTTATTTATTTGCCCACTTTACT
AAAGAGAATTTATTTCTGGA

Downstream 100 bases:

>100_bases
TTATACGTGCTGGTATTATCTGCATGTTTTACTGGAGATATTTACGAGAAGTAAATATATAATCCAAGTAATATAGCTCG
GATATTGTTTATCTCACGTC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MMDSFAIADQYLLAPYELNPTRLQDVFGQILSHRIDYADIYFQYSRSEGWVLEEGIVKSGSFSIDQGVGVRAISGEKTAF
AYSDDISGQALISAARATRAIAAQGSEKQTRIMGLSGNITRQALYYPSLDPIALCQDADKIRLLERLEEFARALDKRVIQ
VMASLAGEYEVIMVARSDGLLAADVRPLVRVSLQVIVEESGQREQGVAGGGGRFDYGYFTDTVLQDYAHKAVHQAITNLV
SKPAPAGSMTVVLGNGWPGILLHEAIGHGLEADFNRKGSSAFSGRIGERVAAPGVTVVDDGTIRDRRGSLNIDDEGNPTQ
CTVLIEDGILKGYLQDNLNARLMNQAVTGNGRRESFAHIPMPRMTNTCMLNGDKEPEEIIASVKHGLYAANFGGGQVDIT
SGKFVFSAAEAYMIENGKITYPVKGATLIGNGPDVLTRVSMIGNDMALDPGVGTCGKEGQSVPVGVGQPTLRVDGLTVGG
TNG

Sequences:

>Translated_483_residues
MMDSFAIADQYLLAPYELNPTRLQDVFGQILSHRIDYADIYFQYSRSEGWVLEEGIVKSGSFSIDQGVGVRAISGEKTAF
AYSDDISGQALISAARATRAIAAQGSEKQTRIMGLSGNITRQALYYPSLDPIALCQDADKIRLLERLEEFARALDKRVIQ
VMASLAGEYEVIMVARSDGLLAADVRPLVRVSLQVIVEESGQREQGVAGGGGRFDYGYFTDTVLQDYAHKAVHQAITNLV
SKPAPAGSMTVVLGNGWPGILLHEAIGHGLEADFNRKGSSAFSGRIGERVAAPGVTVVDDGTIRDRRGSLNIDDEGNPTQ
CTVLIEDGILKGYLQDNLNARLMNQAVTGNGRRESFAHIPMPRMTNTCMLNGDKEPEEIIASVKHGLYAANFGGGQVDIT
SGKFVFSAAEAYMIENGKITYPVKGATLIGNGPDVLTRVSMIGNDMALDPGVGTCGKEGQSVPVGVGQPTLRVDGLTVGG
TNG
>Mature_483_residues
MMDSFAIADQYLLAPYELNPTRLQDVFGQILSHRIDYADIYFQYSRSEGWVLEEGIVKSGSFSIDQGVGVRAISGEKTAF
AYSDDISGQALISAARATRAIAAQGSEKQTRIMGLSGNITRQALYYPSLDPIALCQDADKIRLLERLEEFARALDKRVIQ
VMASLAGEYEVIMVARSDGLLAADVRPLVRVSLQVIVEESGQREQGVAGGGGRFDYGYFTDTVLQDYAHKAVHQAITNLV
SKPAPAGSMTVVLGNGWPGILLHEAIGHGLEADFNRKGSSAFSGRIGERVAAPGVTVVDDGTIRDRRGSLNIDDEGNPTQ
CTVLIEDGILKGYLQDNLNARLMNQAVTGNGRRESFAHIPMPRMTNTCMLNGDKEPEEIIASVKHGLYAANFGGGQVDIT
SGKFVFSAAEAYMIENGKITYPVKGATLIGNGPDVLTRVSMIGNDMALDPGVGTCGKEGQSVPVGVGQPTLRVDGLTVGG
TNG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=58.7991718426501, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1790682, Length=414, Percent_Identity=23.6714975845411, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51670; Mature: 51670

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDSFAIADQYLLAPYELNPTRLQDVFGQILSHRIDYADIYFQYSRSEGWVLEEGIVKSG
CCCCHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCC
SFSIDQGVGVRAISGEKTAFAYSDDISGQALISAARATRAIAAQGSEKQTRIMGLSGNIT
CCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
RQALYYPSLDPIALCQDADKIRLLERLEEFARALDKRVIQVMASLAGEYEVIMVARSDGL
EEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LAADVRPLVRVSLQVIVEESGQREQGVAGGGGRFDYGYFTDTVLQDYAHKAVHQAITNLV
EECCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKPAPAGSMTVVLGNGWPGILLHEAIGHGLEADFNRKGSSAFSGRIGERVAAPGVTVVDD
HCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHCCCCCEEEEC
GTIRDRRGSLNIDDEGNPTQCTVLIEDGILKGYLQDNLNARLMNQAVTGNGRRESFAHIP
CCEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEECC
MPRMTNTCMLNGDKEPEEIIASVKHGLYAANFGGGQVDITSGKFVFSAAEAYMIENGKIT
CCCCCCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCCEEEEECEEEEEECCEEE
YPVKGATLIGNGPDVLTRVSMIGNDMALDPGVGTCGKEGQSVPVGVGQPTLRVDGLTVGG
EEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEEECC
TNG
CCC
>Mature Secondary Structure
MMDSFAIADQYLLAPYELNPTRLQDVFGQILSHRIDYADIYFQYSRSEGWVLEEGIVKSG
CCCCHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCC
SFSIDQGVGVRAISGEKTAFAYSDDISGQALISAARATRAIAAQGSEKQTRIMGLSGNIT
CCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
RQALYYPSLDPIALCQDADKIRLLERLEEFARALDKRVIQVMASLAGEYEVIMVARSDGL
EEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LAADVRPLVRVSLQVIVEESGQREQGVAGGGGRFDYGYFTDTVLQDYAHKAVHQAITNLV
EECCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKPAPAGSMTVVLGNGWPGILLHEAIGHGLEADFNRKGSSAFSGRIGERVAAPGVTVVDD
HCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHCCCCCEEEEC
GTIRDRRGSLNIDDEGNPTQCTVLIEDGILKGYLQDNLNARLMNQAVTGNGRRESFAHIP
CCEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEECC
MPRMTNTCMLNGDKEPEEIIASVKHGLYAANFGGGQVDITSGKFVFSAAEAYMIENGKIT
CCCCCCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCCEEEEECEEEEEECCEEE
YPVKGATLIGNGPDVLTRVSMIGNDMALDPGVGTCGKEGQSVPVGVGQPTLRVDGLTVGG
EEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEEECC
TNG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]