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The map label for this gene is cysS

Identifier: 113477437

GI number: 113477437

Start: 6191034

End: 6192503

Strand: Reverse

Name: cysS

Synonym: Tery_4002

Alternate gene names: 113477437

Gene position: 6192503-6191034 (Counterclockwise)

Preceding gene: 113477441

Following gene: 113477436

Centisome position: 79.9

GC content: 37.28

Gene sequence:

>1470_bases
ATGGCTCTGAAACTATACAATTCACTGACCCGTCAAGAAGAAACCTTTGAACCCTTAGAACCAAACATAATTAAAATGTA
TGTCTGTGGTGTTACAGTATACGACTATTGCCATTTAGGTCATGCTCGTTCCTATATTGCATGGGATACAATGCGCCGGT
ATCTAATATGGCAAGGCTATCAAGTACGGTATGTACAAAATTTTACTGATATAGATGATAAGATTCTTAAGCGGGCTAGA
GAAACAGGAAGTTCTATGGATTCGGTGGCCAAGCGTTTCACGGAAGCATACTTTGAGGACATGAAGCGCTTAAATGTCTT
AGAAGCAGATGAATATCCTCGGGCTACTCAGAATATAGATAGAATTCAGAATTTAATCCATGATTTAGAAAAAAAAGGTT
TTGCTTACTCTTCTGGAGGAGATGTATATTATCAGGTGCGGGAATTTTCCCAATATGGGAAACTCTCAGGCCGTCGTTTA
GAAGAAATGCAAGCTGGCGCAAGTGGTAGGGTAGACTCAGAAGATTTAGAAACTGCCAAAAAGAAAGACCCATTTGATTT
TGCTCTATGGAAAGCGGCAAAAACTGGGGAACCTGCATGGGACTCTCCTTGGGGAAAAGGAAGACCAGGTTGGCATATTG
AATGTTCGGCAATGGTGCAAGATTGTTTAGGGGAAACTATTGATATTCATGCTGGGGGGGCAGATTTAATTTTTCCTCAC
CATGAAAATGAAATTGCTCAGTCGGAAGCTTCTACGGGAAAAATTTTAGCTAGATATTGGCTCCATAATGGTTTTGTTAC
TATCAATGGAGAAAAAATGTCAAAGTCTTTGGGTAATTTTACTACGATTCGGGATTTATTGGATCAACCTGTAGACCCAA
TGGCTTTAAGAATGTTTGTTTTAACTGCTCAATATCGTAAACCTATTGATTTTACTGAAGAGGCGATCGCTTCTGCCAAA
AATGGTTGGAATACTATTAAGGAAGGTATATTATTCCCTTATCAATATGGTCCTAAGTTGGGATGGGAAATGCCCGCAAA
AAATTTATCTGATCAGACATTGTTATTAACTTCTTATCTGGAAAAATTTCAGAAAGCAATGGATGATGATATTAATACTC
CTGCTGCTTTAGCTATTTTATTTGAATTAGCTAAAGATTTACGTCGAGAGGGTAATGTCCTCATACATGAAGGGAAAACT
GAAACATCTTTAGAAGAGTTAAAAAAACAATGGGTAACCCTGGTAAGCTTATCACAAGTATTAGGCTTAGAAGTTAAAAT
AGAAGAACAAGTTAGCAATATATCTGAAGGCTTGAGTAATATTGAAATTGAGTCTTTAATTCAGCAACGTTTAGAAGCAA
AAAAAGCTAAGAATTATTCGGAAGCAGACCGCATTAGAAATGAACTCCAAAGCCAAGGTATTAAACTAATAGATAAATCT
GGTGGTCTAACAAATTGGCATCGGAATTAA

Upstream 100 bases:

>100_bases
AATGGGAAAGTTCCGACACAGGAGGCTTTGGATAGCTGAATAATTATAAAATCTATTCTCCTTATAACTAGAACTAGAAA
AAACTAGGATCAATTAATTT

Downstream 100 bases:

>100_bases
GTAAGTATTTCGGTTAAGTATGTAGATGCAGGAAATAGGGAATAGAAACTCTCCCCAAAATACTAGTGGCTAATTTTGTT
ATTTAGCAGTTGATTAATAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGYQVRYVQNFTDIDDKILKRAR
ETGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNIDRIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRL
EEMQAGASGRVDSEDLETAKKKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPH
HENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFVLTAQYRKPIDFTEEAIASAK
NGWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYLEKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKT
ETSLEELKKQWVTLVSLSQVLGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKS
GGLTNWHRN

Sequences:

>Translated_489_residues
MALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGYQVRYVQNFTDIDDKILKRAR
ETGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNIDRIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRL
EEMQAGASGRVDSEDLETAKKKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPH
HENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFVLTAQYRKPIDFTEEAIASAK
NGWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYLEKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKT
ETSLEELKKQWVTLVSLSQVLGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKS
GGLTNWHRN
>Mature_488_residues
ALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGYQVRYVQNFTDIDDKILKRARE
TGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNIDRIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRLE
EMQAGASGRVDSEDLETAKKKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPHH
ENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFVLTAQYRKPIDFTEEAIASAKN
GWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYLEKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKTE
TSLEELKKQWVTLVSLSQVLGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKSG
GLTNWHRN

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=516, Percent_Identity=33.3333333333333, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI10835051, Length=248, Percent_Identity=43.5483870967742, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI21269877, Length=248, Percent_Identity=43.5483870967742, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI62240992, Length=248, Percent_Identity=43.5483870967742, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI303304987, Length=248, Percent_Identity=43.5483870967742, Blast_Score=193, Evalue=4e-49,
Organism=Escherichia coli, GI1786737, Length=490, Percent_Identity=42.6530612244898, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17509797, Length=251, Percent_Identity=39.4422310756972, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17509795, Length=251, Percent_Identity=39.4422310756972, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=422, Percent_Identity=32.4644549763033, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19922218, Length=517, Percent_Identity=31.1411992263056, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI19922364, Length=353, Percent_Identity=35.4107648725212, Blast_Score=196, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_TRIEI (Q10XJ9)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_723498.1
- ProteinModelPortal:   Q10XJ9
- SMR:   Q10XJ9
- STRING:   Q10XJ9
- GeneID:   4244569
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_4002
- NMPDR:   fig|203124.1.peg.5144
- eggNOG:   COG0215
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- PhylomeDB:   Q10XJ9
- ProtClustDB:   PRK00260
- BioCyc:   TERY203124:TERY_4002-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 55883; Mature: 55752

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 275-275

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGY
CCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
QVRYVQNFTDIDDKILKRARETGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNID
EEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRLEEMQAGASGRVDSEDLETAK
HHHHHHHHHHHCCCEECCCCCEEHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHH
KKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPH
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCC
HENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFV
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHH
LTAQYRKPIDFTEEAIASAKNGWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYL
HHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKTETSLEELKKQWVTLVSLSQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
LGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKS
HCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECC
GGLTNWHRN
CCCCCCCCC
>Mature Secondary Structure 
ALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGY
CCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
QVRYVQNFTDIDDKILKRARETGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNID
EEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRLEEMQAGASGRVDSEDLETAK
HHHHHHHHHHHCCCEECCCCCEEHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHH
KKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPH
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCC
HENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFV
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHH
LTAQYRKPIDFTEEAIASAKNGWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYL
HHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKTETSLEELKKQWVTLVSLSQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
LGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKS
HCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECC
GGLTNWHRN
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA