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The map label for this gene is glsA [H]

Identifier: 113477426

GI number: 113477426

Start: 6168208

End: 6169122

Strand: Reverse

Name: glsA [H]

Synonym: Tery_3991

Alternate gene names: 113477426

Gene position: 6169122-6168208 (Counterclockwise)

Preceding gene: 113477428

Following gene: 113477421

Centisome position: 79.6

GC content: 29.95

Gene sequence:

>915_bases
ATGTTTAAAAATTTATCAAACATTAATCAACAACAACTAAATACTTGGGTCAAACAAGTATTAACTCAAACTAAATCTGG
CAATTTGCCTAACTATATTCCTTTACTTGCAGAAGCTAACCCTAACAGTTTTGCCATACTTTTACAAAGTATTGATCATC
ATATCATTTCATTCGGAGATATCAAAACTAAAGTTCCTTTGATGAGTGCAATAAAACCATTTTTGTTATTTTATTTATTA
TCTCAATTTGGCAATGAATTGATCTTTAAAAAAGTCGGTCAAAAACCTTCAGAAAAGCCATTCAATTCTTTAGAACAACT
AGAATTTGATGGGGGATGGCCGAGAAATCCTATGATTAATAGTGGAGCGATCGCTTTATCATCCTTAATACCAGGAAATA
CTGCTAGAGAAAAGTGCAATAATTTTTGTTCTTGGCTAAATAGTTACGGAAATTGTCAATTATTTTTAGATGAAAATATG
TTGGCTTCGGTTCGTTCTTTACCTAACCAGAATAATCAAAATATAGCTCAAAAATTAGTAGAATCTGGTTCTATAAAAGA
TGCTAAAATTACTTTAGATACTTACAATCAAATCTGTTGTTTATCTGGTAAAATTATTGATATAGCTAATCTAGGAATTT
TATTAGTAAACTCACCTCATTCTGAATGGCAAAAACACTGTTTTACAGTTAAAACACTGATGACTAATTGTGGTTTATAT
GAAACATCAAATCGTTATGCTATGGATATAGGAATTCCAATTAAATCTAGTATCAGTGGAATTGTTTTAGGATTAGTTCC
TGCTAAAGGAGTAATTGTTTGCTATAGTCCTCCCCTCGATCAACAAGGAAATTCTGTAGCAGGTTTACTTTTGTTAGAAC
TAATTTCCAGAAATTTAGAAAAACAATATAATTAA

Upstream 100 bases:

>100_bases
TCTTACTCTTTGAATAAACCTCCAGTAAAAACAATATTTGGTATAAGTCCTGTCTCCTCACTAATTTATTTTACTTTCAG
TTGAGTCAGTAAAGATATTT

Downstream 100 bases:

>100_bases
TTTTAATTATTAACTTTAATTAAATATCAATATTTATAGAAAATTCTACAAATAACGCAACATCTTTCTCCAGAATTTTA
CTGAAATTGTATTTATACTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MFKNLSNINQQQLNTWVKQVLTQTKSGNLPNYIPLLAEANPNSFAILLQSIDHHIISFGDIKTKVPLMSAIKPFLLFYLL
SQFGNELIFKKVGQKPSEKPFNSLEQLEFDGGWPRNPMINSGAIALSSLIPGNTAREKCNNFCSWLNSYGNCQLFLDENM
LASVRSLPNQNNQNIAQKLVESGSIKDAKITLDTYNQICCLSGKIIDIANLGILLVNSPHSEWQKHCFTVKTLMTNCGLY
ETSNRYAMDIGIPIKSSISGIVLGLVPAKGVIVCYSPPLDQQGNSVAGLLLLELISRNLEKQYN

Sequences:

>Translated_304_residues
MFKNLSNINQQQLNTWVKQVLTQTKSGNLPNYIPLLAEANPNSFAILLQSIDHHIISFGDIKTKVPLMSAIKPFLLFYLL
SQFGNELIFKKVGQKPSEKPFNSLEQLEFDGGWPRNPMINSGAIALSSLIPGNTAREKCNNFCSWLNSYGNCQLFLDENM
LASVRSLPNQNNQNIAQKLVESGSIKDAKITLDTYNQICCLSGKIIDIANLGILLVNSPHSEWQKHCFTVKTLMTNCGLY
ETSNRYAMDIGIPIKSSISGIVLGLVPAKGVIVCYSPPLDQQGNSVAGLLLLELISRNLEKQYN
>Mature_304_residues
MFKNLSNINQQQLNTWVKQVLTQTKSGNLPNYIPLLAEANPNSFAILLQSIDHHIISFGDIKTKVPLMSAIKPFLLFYLL
SQFGNELIFKKVGQKPSEKPFNSLEQLEFDGGWPRNPMINSGAIALSSLIPGNTAREKCNNFCSWLNSYGNCQLFLDENM
LASVRSLPNQNNQNIAQKLVESGSIKDAKITLDTYNQICCLSGKIIDIANLGILLVNSPHSEWQKHCFTVKTLMTNCGLY
ETSNRYAMDIGIPIKSSISGIVLGLVPAKGVIVCYSPPLDQQGNSVAGLLLLELISRNLEKQYN

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI20336214, Length=292, Percent_Identity=30.8219178082192, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI156104878, Length=278, Percent_Identity=31.294964028777, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=26.9736842105263, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=30.03300330033, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17532727, Length=302, Percent_Identity=31.7880794701987, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193204073, Length=298, Percent_Identity=28.8590604026846, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193204075, Length=300, Percent_Identity=28.6666666666667, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17507019, Length=291, Percent_Identity=30.5841924398625, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24653158, Length=289, Percent_Identity=30.7958477508651, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653162, Length=289, Percent_Identity=30.7958477508651, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363239, Length=283, Percent_Identity=30.7420494699647, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363241, Length=283, Percent_Identity=30.7420494699647, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653164, Length=289, Percent_Identity=30.7958477508651, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653156, Length=289, Percent_Identity=30.7958477508651, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI116008307, Length=289, Percent_Identity=30.7958477508651, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653166, Length=289, Percent_Identity=30.7958477508651, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33708; Mature: 33708

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNLSNINQQQLNTWVKQVLTQTKSGNLPNYIPLLAEANPNSFAILLQSIDHHIISFGD
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEECCC
IKTKVPLMSAIKPFLLFYLLSQFGNELIFKKVGQKPSEKPFNSLEQLEFDGGWPRNPMIN
HHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCC
SGAIALSSLIPGNTAREKCNNFCSWLNSYGNCQLFLDENMLASVRSLPNQNNQNIAQKLV
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHH
ESGSIKDAKITLDTYNQICCLSGKIIDIANLGILLVNSPHSEWQKHCFTVKTLMTNCGLY
HCCCCCCEEEEEECCCCEEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCE
ETSNRYAMDIGIPIKSSISGIVLGLVPAKGVIVCYSPPLDQQGNSVAGLLLLELISRNLE
ECCCCEEEEECCCHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KQYN
HCCC
>Mature Secondary Structure
MFKNLSNINQQQLNTWVKQVLTQTKSGNLPNYIPLLAEANPNSFAILLQSIDHHIISFGD
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEECCC
IKTKVPLMSAIKPFLLFYLLSQFGNELIFKKVGQKPSEKPFNSLEQLEFDGGWPRNPMIN
HHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCC
SGAIALSSLIPGNTAREKCNNFCSWLNSYGNCQLFLDENMLASVRSLPNQNNQNIAQKLV
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHH
ESGSIKDAKITLDTYNQICCLSGKIIDIANLGILLVNSPHSEWQKHCFTVKTLMTNCGLY
HCCCCCCEEEEEECCCCEEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCE
ETSNRYAMDIGIPIKSSISGIVLGLVPAKGVIVCYSPPLDQQGNSVAGLLLLELISRNLE
ECCCCEEEEECCCHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KQYN
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]