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The map label for this gene is trpF

Identifier: 113477364

GI number: 113477364

Start: 6056265

End: 6056957

Strand: Reverse

Name: trpF

Synonym: Tery_3920

Alternate gene names: 113477364

Gene position: 6056957-6056265 (Counterclockwise)

Preceding gene: 113477367

Following gene: 113477363

Centisome position: 78.15

GC content: 32.76

Gene sequence:

>693_bases
ATGCGCATCAAAATTTGTGGAATTACAAAACTAGACCAAGGACAAGCGATCGCCGAGATAGGAGCAACAGCTCTAGGATT
TATCTGTGTTCCCAAATCACCCCGCTATATTACCCCAGAAAACATCAAAAATATTATCCAGAAACTACCAATAAATATTG
ACAAAATAGGAGTATTTGTTAATCCTAAAATAGACTTATTATCAGAAATAATTACTAATACCCAACTAAATGGAATACAA
CTACATGGTGACGAATCCCCAGAATTTTGTAATCAGCTACGTCATTCAATACCAAATAATATAGAAATAATTAAAGCCCT
CAGAATTAAATCTCCTCAAGACCTAAAAAAAGCAAATATTTATGAAAACTATATTGATACTTTACTTCTAGATGCTTATC
ATCCAGAAAAATTAGGTGGCACTGGTAAAACCTTAGACTGGAAAATCATTGAAGAATTTCATCCTACTTCTCCTTGGTTA
TTAGCAGGTGGTTTAACCCCAGAAAATGTAACAAAAGCAATACAAAAATTCATATTAGTCTCTCAAACTCAAATAGAATC
TAATCACAAATTTAATCATAACTTTTGTGGCATAGATCTATCTAGTGGTGTAGAGACAGCACCAGGGGATAAAAACTTAG
TAAAAGTCAGAAAATTATTCAGTAGTTTGGCAACACTTACGATGAAAAAGTAG

Upstream 100 bases:

>100_bases
AAGAAACTTGAGTTAAAAGCTATAATTTGTGTTAATAATTAACAGTAATTTTAAAATTTAATACAGAAGTATTAAACTTA
ATTAGTAGTAGGTATAATTA

Downstream 100 bases:

>100_bases
AAATAATACCAAGTATTATATATAGTAAAACTTCATAGTATCTTCCTCAAATATTCATAATAAATTTTCCACCTAATTTT
ACAAATAAAGCTAAACCATG

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRIKICGITKLDQGQAIAEIGATALGFICVPKSPRYITPENIKNIIQKLPINIDKIGVFVNPKIDLLSEIITNTQLNGIQ
LHGDESPEFCNQLRHSIPNNIEIIKALRIKSPQDLKKANIYENYIDTLLLDAYHPEKLGGTGKTLDWKIIEEFHPTSPWL
LAGGLTPENVTKAIQKFILVSQTQIESNHKFNHNFCGIDLSSGVETAPGDKNLVKVRKLFSSLATLTMKK

Sequences:

>Translated_230_residues
MRIKICGITKLDQGQAIAEIGATALGFICVPKSPRYITPENIKNIIQKLPINIDKIGVFVNPKIDLLSEIITNTQLNGIQ
LHGDESPEFCNQLRHSIPNNIEIIKALRIKSPQDLKKANIYENYIDTLLLDAYHPEKLGGTGKTLDWKIIEEFHPTSPWL
LAGGLTPENVTKAIQKFILVSQTQIESNHKFNHNFCGIDLSSGVETAPGDKNLVKVRKLFSSLATLTMKK
>Mature_230_residues
MRIKICGITKLDQGQAIAEIGATALGFICVPKSPRYITPENIKNIIQKLPINIDKIGVFVNPKIDLLSEIITNTQLNGIQ
LHGDESPEFCNQLRHSIPNNIEIIKALRIKSPQDLKKANIYENYIDTLLLDAYHPEKLGGTGKTLDWKIIEEFHPTSPWL
LAGGLTPENVTKAIQKFILVSQTQIESNHKFNHNFCGIDLSSGVETAPGDKNLVKVRKLFSSLATLTMKK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Escherichia coli, GI87081863, Length=220, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_TRIEI (Q10XS2)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_723425.1
- ProteinModelPortal:   Q10XS2
- SMR:   Q10XS2
- STRING:   Q10XS2
- GeneID:   4244003
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3920
- NMPDR:   fig|203124.1.peg.5051
- eggNOG:   COG0135
- HOGENOM:   HBG554803
- OMA:   SKICGIT
- PhylomeDB:   Q10XS2
- ProtClustDB:   PRK01222
- BioCyc:   TERY203124:TERY_3920-MONOMER
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 25621; Mature: 25621

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKICGITKLDQGQAIAEIGATALGFICVPKSPRYITPENIKNIIQKLPINIDKIGVFV
CEEEEECCCCCCCCCHHHHHHHHHEEEEECCCCCCEECHHHHHHHHHHCCCCEEHEEEEE
NPKIDLLSEIITNTQLNGIQLHGDESPEFCNQLRHSIPNNIEIIKALRIKSPQDLKKANI
CCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHH
YENYIDTLLLDAYHPEKLGGTGKTLDWKIIEEFHPTSPWLLAGGLTPENVTKAIQKFILV
HHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
SQTQIESNHKFNHNFCGIDLSSGVETAPGDKNLVKVRKLFSSLATLTMKK
HHHHHCCCCCCCCCEECEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIKICGITKLDQGQAIAEIGATALGFICVPKSPRYITPENIKNIIQKLPINIDKIGVFV
CEEEEECCCCCCCCCHHHHHHHHHEEEEECCCCCCEECHHHHHHHHHHCCCCEEHEEEEE
NPKIDLLSEIITNTQLNGIQLHGDESPEFCNQLRHSIPNNIEIIKALRIKSPQDLKKANI
CCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHH
YENYIDTLLLDAYHPEKLGGTGKTLDWKIIEEFHPTSPWLLAGGLTPENVTKAIQKFILV
HHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
SQTQIESNHKFNHNFCGIDLSSGVETAPGDKNLVKVRKLFSSLATLTMKK
HHHHHCCCCCCCCCEECEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA