Click here to switch to the map view.

The map label for this gene is ubiB [H]

Identifier: 113477283

GI number: 113477283

Start: 5900218

End: 5901993

Strand: Reverse

Name: ubiB [H]

Synonym: Tery_3828

Alternate gene names: 113477283

Gene position: 5901993-5900218 (Counterclockwise)

Preceding gene: 113477284

Following gene: 113477269

Centisome position: 76.15

GC content: 34.85

Gene sequence:

>1776_bases
ATGCTAAACAAGAAATATATTCCAACACCGCTGATTGAGAAAAAGAAAAAGAAAAAAGTAAAGATTGTAGAAAAAATAGA
TAAGCGACGAGTCACGACTCCTTATGTTATTCGGCGATTCATTATTTATTTTTTAGCCCTACAGTGGCGCAGATTTACTG
GCAAAGCAAATATGGAAAAAACAGCAACTCAATTGCGAGAAATATTTGAAGATTTTGGTGGTTTTTGGGTAAAAGCAGGT
CAGGTTTTAGCACTACGAACAGATATTTTACCAGAACCTATATGTGATGCCTTACAAAGTTTACAGTCTGAAGCACTTGG
TTTTCCTTTTGATATTGTACGCTCAACTATTGAGTCAGAATTGGGTGTTCCTTTGAAGAAAGTTTTTGCCGTTTTTGATG
AGGAACCCTTAGCAGCAGCTTCTATTGCTCAAGTTCATACTGCGGTTTTGCGTAAAAAACAAATCCCTGTAGTCGTGAAA
GTTCAGCGTCCTGGTTTAGAAGATGCTTTCCAGCGAGATTTAAATGTTATTAAGGGTCTGGTTAATCTATTAATTTTCTT
GAATATTGCTACTTATTTAGGTTGGGGTGAATTTATTGCAGAGTTAGATAAAACCTTTAAAGAAGAACTAGATTTCAGAT
ATGAAGCAAGCAGTACTATTAGGATGAGAAAGTCCCTTAAAGAACATAAAGTTTTCGTTCCAAAGATATACGAAAAATAT
TCTAAACGTCGGATTTTGGTAATGGAATTTATAAATGGTGTAATGATGTCAGACTATATTACTGCCCTAGCAAGTCAACG
TTCTCTAGCTGCGAAGTGGGAGGAGGAAAATAACATTGATAGAGTCAAACTTGGGGAAAGGTTATACTTGTCCTTGTTCC
GACAACTATTTGAAGACAATCTATTTCATGCTGACTTACATCCAGGTAATATAATATTGTTGCGTAATAACAAGTTTGTA
CTCATTGATCATGGTAGTACAGGTTCTTTGGAAGCAGAATTAAGGAATACTTACTTGAATTATGTTAATGGTTTAGGGGA
AGGAAATTTTACCAAAGCAGCTGATTACTATATTCGATTTGGTGTTGGTATTCCTAAAGTTGATATTGATAGAGTGCGAG
TAGAGATGGGGCGTCAGTTTGAGAACTGGTATGTCAGATCTCAAGTTAAAGGAGTACCGTTTCGGCAAAAATCTTTAGGT
GGAGCTATTAAAGGAGTAACTGATGTAGCTTTTGGTTATAAAATCCCTACTAACTGGGATTTTTTAAAACTTACTAGGTC
TGTTCTAGCATTAGATGGTTCACTGCAATATCTATGGCCAGATATAGATGTCTTTGAAGTTATTAATAAGTATAACAAAC
AAGCACGGCGTCGTGCTTTAGTAAATAATCTACGTCCTGAGAATATTCTTAAATGGGTTAACCAAGCTTCAGATATTGTT
AATCAGTATAATTATTTAGTCTTGCCAGAAGTTAGAAAGCGAACAAATGCTTATGAATTGACAGTTAATCAGTTTGCTCT
CTCAATGGTAGTGATTTTGAGGAGGTCATCTTATCTAGTGCTGGTCGCTGAATTTGGTGCACTGTATGTATTCCTTTATC
AACACTATTTTCAAATTATTCGGCCAATTAATATTCAAATGATTGATGAAATAGTTAGTAAGTTCCCATATATACCATAC
TTGGAGTGGGTGGGAATATTAATTGTTGTAGGATTGATTTTCCAAGTTTTATTAGTTTGTGCAAAAATCTTAGGACGCAA
AGAGTTAAATATTTAA

Upstream 100 bases:

>100_bases
GATCTATAAATATGCTGAATCTAAACTATATTTAGATTTCTAGAGATTTGTAATTCAAAATTATAAACAGAAAGCTACGT
CTTGTCTAAGATATAATAGG

Downstream 100 bases:

>100_bases
GGTTAGCTAAAAGAAGATATTAAAGTACAGTTTAATATTACTCTTATTATCCTTTTTGGCTTTTCCCTCTTGACCTGGAG
ACATTTCTAAAAAATAATTT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEKTATQLREIFEDFGGFWVKAG
QVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESELGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVK
VQRPGLEDAFQRDLNVIKGLVNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKY
SKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDNLFHADLHPGNIILLRNNKFV
LIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRFGVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLG
GAIKGVTDVAFGYKIPTNWDFLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIV
NQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQIIRPINIQMIDEIVSKFPYIPY
LEWVGILIVVGLIFQVLLVCAKILGRKELNI

Sequences:

>Translated_591_residues
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEKTATQLREIFEDFGGFWVKAG
QVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESELGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVK
VQRPGLEDAFQRDLNVIKGLVNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKY
SKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDNLFHADLHPGNIILLRNNKFV
LIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRFGVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLG
GAIKGVTDVAFGYKIPTNWDFLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIV
NQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQIIRPINIQMIDEIVSKFPYIPY
LEWVGILIVVGLIFQVLLVCAKILGRKELNI
>Mature_591_residues
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEKTATQLREIFEDFGGFWVKAG
QVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESELGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVK
VQRPGLEDAFQRDLNVIKGLVNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKY
SKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDNLFHADLHPGNIILLRNNKFV
LIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRFGVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLG
GAIKGVTDVAFGYKIPTNWDFLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIV
NQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQIIRPINIQMIDEIVSKFPYIPY
LEWVGILIVVGLIFQVLLVCAKILGRKELNI

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=310, Percent_Identity=28.7096774193548, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI41393593, Length=268, Percent_Identity=30.5970149253731, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI217035081, Length=299, Percent_Identity=28.4280936454849, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI34147522, Length=298, Percent_Identity=25.1677852348993, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI27363457, Length=305, Percent_Identity=25.9016393442623, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI217416386, Length=239, Percent_Identity=27.6150627615063, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI2367309, Length=442, Percent_Identity=28.2805429864253, Blast_Score=162, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=289, Percent_Identity=29.0657439446367, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32565180, Length=321, Percent_Identity=23.6760124610592, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=272, Percent_Identity=27.2058823529412, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=268, Percent_Identity=29.8507462686567, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325148, Length=294, Percent_Identity=24.1496598639456, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI22024280, Length=306, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24662575, Length=289, Percent_Identity=32.1799307958478, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859849, Length=284, Percent_Identity=25.3521126760563, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 68493; Mature: 68493

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
TATQLREIFEDFGGFWVKAGQVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESE
HHHHHHHHHHHHCCCEEECCCEEEEEHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVKVQRPGLEDAFQRDLNVIKGL
HCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
VNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
SKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDN
HCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LFHADLHPGNIILLRNNKFVLIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRF
CEEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEE
GVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLGGAIKGVTDVAFGYKIPTNWD
CCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCH
FLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIV
HHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQII
HHCCEEEECHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
RPINIQMIDEIVSKFPYIPYLEWVGILIVVGLIFQVLLVCAKILGRKELNI
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
TATQLREIFEDFGGFWVKAGQVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESE
HHHHHHHHHHHHCCCEEECCCEEEEEHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVKVQRPGLEDAFQRDLNVIKGL
HCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
VNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
SKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDN
HCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LFHADLHPGNIILLRNNKFVLIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRF
CEEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEE
GVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLGGAIKGVTDVAFGYKIPTNWD
CCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCH
FLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIV
HHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQII
HHCCEEEECHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
RPINIQMIDEIVSKFPYIPYLEWVGILIVVGLIFQVLLVCAKILGRKELNI
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA