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The map label for this gene is frr

Identifier: 113477237

GI number: 113477237

Start: 5808254

End: 5808802

Strand: Reverse

Name: frr

Synonym: Tery_3778

Alternate gene names: 113477237

Gene position: 5808802-5808254 (Counterclockwise)

Preceding gene: 113477238

Following gene: 113477236

Centisome position: 74.95

GC content: 34.79

Gene sequence:

>549_bases
ATGAATCTAAAAGAAGCTGAAGAGAAAATGCAAAAAGCTATTGAAGCGACTAAAAATTCCTTCAATACTGTTAGAACTGG
AAGAGCTAATGCTTCTCTTTTGGACAGAGTAATGGTGGAGTATTATGGATCCCCAACTCAACTCAAATCTATGGCAAATA
TTGGCATCCCAGATGCTAGTACAATTACTATTCAACCTTATGATAAAACCAGTCTCGGCTTGATTGAAAAAGCTATTAAT
ATGTCAGATGTTGGTTTAACTCCTAACAATGATGGGTCTATTATACGGTTAAATATACCAGCACTAACAGCTGAACGTCG
TCAAGAAATGGTTAAAAAAACAGCAAAACTTGCTGAAGAGGGGAAAGTTTCTATCCGGAATATTCGTCGTGATGCGGTAG
ATTCAATTCGTAAACAAGAAAAAAATAGTGATATTTCTAAAGATGAATCACGAGATTTGCAAGACAAAGTTCAAAAGAAG
ACTGATAAATATATTGCCAAAATAGATGAGTTACTAGCTGCTAAAGAGAAGGATATGACTACAGTTTAA

Upstream 100 bases:

>100_bases
GAAAATAATATCCCAATTATTGTATTTAACCTTTCAGTTTCGGGTAATATCTGTAAAGCTGTTATGGGAGAAAAAATTGG
AACTATTGTAGGAGGTTTTC

Downstream 100 bases:

>100_bases
AAAAAAATACCACAGATAAAAAAGCTATCAGCTATTAACTATTAGCTATTATTTATTAAATAATTATCTGGGAAATAAAA
ATCAGTCTCCATGGATAAGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNLKEAEEKMQKAIEATKNSFNTVRTGRANASLLDRVMVEYYGSPTQLKSMANIGIPDASTITIQPYDKTSLGLIEKAIN
MSDVGLTPNNDGSIIRLNIPALTAERRQEMVKKTAKLAEEGKVSIRNIRRDAVDSIRKQEKNSDISKDESRDLQDKVQKK
TDKYIAKIDELLAAKEKDMTTV

Sequences:

>Translated_182_residues
MNLKEAEEKMQKAIEATKNSFNTVRTGRANASLLDRVMVEYYGSPTQLKSMANIGIPDASTITIQPYDKTSLGLIEKAIN
MSDVGLTPNNDGSIIRLNIPALTAERRQEMVKKTAKLAEEGKVSIRNIRRDAVDSIRKQEKNSDISKDESRDLQDKVQKK
TDKYIAKIDELLAAKEKDMTTV
>Mature_182_residues
MNLKEAEEKMQKAIEATKNSFNTVRTGRANASLLDRVMVEYYGSPTQLKSMANIGIPDASTITIQPYDKTSLGLIEKAIN
MSDVGLTPNNDGSIIRLNIPALTAERRQEMVKKTAKLAEEGKVSIRNIRRDAVDSIRKQEKNSDISKDESRDLQDKVQKK
TDKYIAKIDELLAAKEKDMTTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=27.6243093922652, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786368, Length=176, Percent_Identity=45.4545454545455, Blast_Score=157, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24661488, Length=181, Percent_Identity=26.5193370165746, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_TRIEI (Q10Y49)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_723298.1
- ProteinModelPortal:   Q10Y49
- SMR:   Q10Y49
- STRING:   Q10Y49
- GeneID:   4243726
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3778
- NMPDR:   fig|203124.1.peg.995
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   TERY203124:TERY_3778-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20360; Mature: 20360

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKEAEEKMQKAIEATKNSFNTVRTGRANASLLDRVMVEYYGSPTQLKSMANIGIPDAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
TITIQPYDKTSLGLIEKAINMSDVGLTPNNDGSIIRLNIPALTAERRQEMVKKTAKLAEE
EEEECCCCCHHHHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
GKVSIRNIRRDAVDSIRKQEKNSDISKDESRDLQDKVQKKTDKYIAKIDELLAAKEKDMT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TV
CC
>Mature Secondary Structure
MNLKEAEEKMQKAIEATKNSFNTVRTGRANASLLDRVMVEYYGSPTQLKSMANIGIPDAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
TITIQPYDKTSLGLIEKAINMSDVGLTPNNDGSIIRLNIPALTAERRQEMVKKTAKLAEE
EEEECCCCCHHHHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
GKVSIRNIRRDAVDSIRKQEKNSDISKDESRDLQDKVQKKTDKYIAKIDELLAAKEKDMT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA