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The map label for this gene is yeiG [C]

Identifier: 113476424

GI number: 113476424

Start: 4410979

End: 4411827

Strand: Reverse

Name: yeiG [C]

Synonym: Tery_2838

Alternate gene names: 113476424

Gene position: 4411827-4410979 (Counterclockwise)

Preceding gene: 113476426

Following gene: 113476421

Centisome position: 56.93

GC content: 33.92

Gene sequence:

>849_bases
ATGTCTACAAAAATTAAATTGGTTAAAAAACATCAATGCTTTGGTGGTACAGTAAGCTATTATTTCCACTCATCTTCCAC
CTGTAATACTGAAATGCGTTTCTCAATTTACCAACCATCGCTAGCAAAATCACAACCTCTTCCTATTCTGTATTTTCTCT
CAGGTTTAACCTGTACTGAAGAGAACTTTATGGCTAAAGCAGGAGCGCAACAATTTGCTAATAAATATGGGTTAATTTTA
GTTGTACCAGATACAAGCCCACGAAATACTGGTACTTTTGGAGAGGATGATGATTGGGATTTAGGTACAGGTGCAGGATT
CTATATTAACGCTACTGTAGAACCTTGGAAAAAGCACTATCAAATGTATAGTTATGTCGTCGAAGAACTACCAGAAATTA
TTGCCAAAAATTTTCCTGTACAACCAGATAAGCAAAGTATTTTCGGTCACTCTATGGGAGGTCATGGAGCACTAATTTGT
GCTTTGAAAAATCCTGAAAAATATCAATCTGTTTCCGCCTTTGCTCCAATTGCAGCACCTATGCGTTGTTATTGGGGAAA
GAAAGCTTTTAGGAATTATTTAGGTACAAACACAAAAAATTGGCGTGATTATGATGCTAGTGAATTAGTTTTAACTTATA
AGTATAATCGTCCAATTTTAATTGATGTAGGAACTGTAGATCCTTTTTTAGCTCAAAAGCAATTACTCCCAGAAGTGTTT
GAAAGTGCTTGTCAAAAAGTTGGTTTACCACTAACTTTAAGAATGCTAAAAAATTATGATCATAGCTATTATTTCATTAC
ATCTTTTATTGAAGATCATATTCGTTATCATTCTGAATTTTTAAACTGA

Upstream 100 bases:

>100_bases
TCCCTTATGCGCTTTCTCTTATTCAAGGAAATAAAAAAAATCATGTTTCAAACCTCCGGCTTCAGAAGTCAGCATTAATA
ATAGAAAACTGAAATGACTT

Downstream 100 bases:

>100_bases
ATCAAAACTATAAGCACTTAAACACTCATTGCAGGCCTCGGCTAATTTGATGTGAGAGATATAGTATAAGTAATTCGGCT
TGGAAAAATGTGTAGTTAAT

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSTKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTEENFMAKAGAQQFANKYGLIL
VVPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHYQMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALIC
ALKNPEKYQSVSAFAPIAAPMRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVF
ESACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN

Sequences:

>Translated_282_residues
MSTKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTEENFMAKAGAQQFANKYGLIL
VVPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHYQMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALIC
ALKNPEKYQSVSAFAPIAAPMRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVF
ESACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN
>Mature_281_residues
STKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTEENFMAKAGAQQFANKYGLILV
VPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHYQMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALICA
LKNPEKYQSVSAFAPIAAPMRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVFE
SACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=279, Percent_Identity=55.1971326164875, Blast_Score=336, Evalue=1e-92,
Organism=Escherichia coli, GI1788477, Length=279, Percent_Identity=50.8960573476703, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1786551, Length=278, Percent_Identity=45.6834532374101, Blast_Score=267, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=49.4623655913978, Blast_Score=271, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322393, Length=297, Percent_Identity=38.3838383838384, Blast_Score=204, Evalue=9e-54,
Organism=Drosophila melanogaster, GI45551932, Length=280, Percent_Identity=50.7142857142857, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24648347, Length=280, Percent_Identity=50.7142857142857, Blast_Score=296, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 32144; Mature: 32013

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTE
CCCCEEEEEHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCEECC
ENFMAKAGAQQFANKYGLILVVPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHY
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHH
QMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALICALKNPEKYQSVSAFAPIAAP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHH
MRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVF
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHH
ESACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN
HHHHHHCCCCEEEHHHHCCCCCEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTE
CCCEEEEEHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCEECC
ENFMAKAGAQQFANKYGLILVVPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHY
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHH
QMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALICALKNPEKYQSVSAFAPIAAP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHH
MRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVF
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHH
ESACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN
HHHHHHCCCCEEEHHHHCCCCCEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]