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The map label for this gene is potC [H]

Identifier: 113476405

GI number: 113476405

Start: 4378464

End: 4379327

Strand: Reverse

Name: potC [H]

Synonym: Tery_2817

Alternate gene names: 113476405

Gene position: 4379327-4378464 (Counterclockwise)

Preceding gene: 113476406

Following gene: 113476404

Centisome position: 56.51

GC content: 32.99

Gene sequence:

>864_bases
ATGAAACAAATTGATTTATTTATTCGTTCTGTTGGCAAATTCGGTTTATGGCTAAATGCGACTTTTAGTTTCGCCTTTCT
TTATCTACCTATTTTGATATTAGTAATTTACTCCTTTAATAATTCCCGTTTTAATGCTGTATGGCGAGGTTTTACTTTAA
AATGGTATGACAATTTATTACAAGAATTTTCGGCTAATGCTATTAGCAATGTGATGATTTGGGAAGCCCTAACAAATAGT
CTTTTTGTAGCAACAATTTCAACATTGCTAGCAACAATTTTTGGTACTATGATTGCTTTAGCATTAGAACGTTTTCGTTT
TCCCGGACGTAATGTTTTAGAGGCCATACTTTTTTTGCCGATAATTATACCCGAAATTACTATTGGTATTTCTTTATTAG
TTTTCTTTTCCTTGGGGTTTCAGCTAATCGAAAATATTTTAGGTATTCGTTTAGTTTTAGGTTTGCCGACAGTAATTATT
GGTCATATAGTGTTTAGTATCTCTTTTGTTGTTGTAACTGTCAGAGCGCGAGTAGCTCAACTTGACCCGGCTTTAGAAGA
AGCTGCTTTAGACCTGGGTGCTAATGAATGGAAAACTTTTTTTCAGATTACTTTACCTTTAATTTGGCCGGCAATTTTTA
GTGCTGCTTTGTTAGCTTTTACCTTGTCATTAGATGATTTTGTGATTACTTTTTTCACTGCTGGAGTCGGCTCAACAACA
TTACCATTATTTGTTTATGGTATGATTAAATTTTCGGTAACTCCAGCCATTAATGCTATATCAACTTTGATGTTAGTAGC
TTCTTTAATTTTGGTGGCATCTTCTCTTTTTATTGATAAATTGGGCAATAAAAAAAATGCCTAA

Upstream 100 bases:

>100_bases
AAGAGTAGCTTTCATACTTTATTTATGCTTCATTAATTAACCTTAAGGTAAGTTTTCTGTAAGGTTATTACCATTTATCA
CACTCAAGATAAAAGCGAGA

Downstream 100 bases:

>100_bases
AATTACCGAAAAAAAAGAAAGAATAAAAAGGGAAGATGGAGGCAGGAAAAAGGAAAGTAGATAAGTCTATAGACCAATAC
AGTTTAGTTAAGATTTTTTT

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKQIDLFIRSVGKFGLWLNATFSFAFLYLPILILVIYSFNNSRFNAVWRGFTLKWYDNLLQEFSANAISNVMIWEALTNS
LFVATISTLLATIFGTMIALALERFRFPGRNVLEAILFLPIIIPEITIGISLLVFFSLGFQLIENILGIRLVLGLPTVII
GHIVFSISFVVVTVRARVAQLDPALEEAALDLGANEWKTFFQITLPLIWPAIFSAALLAFTLSLDDFVITFFTAGVGSTT
LPLFVYGMIKFSVTPAINAISTLMLVASLILVASSLFIDKLGNKKNA

Sequences:

>Translated_287_residues
MKQIDLFIRSVGKFGLWLNATFSFAFLYLPILILVIYSFNNSRFNAVWRGFTLKWYDNLLQEFSANAISNVMIWEALTNS
LFVATISTLLATIFGTMIALALERFRFPGRNVLEAILFLPIIIPEITIGISLLVFFSLGFQLIENILGIRLVLGLPTVII
GHIVFSISFVVVTVRARVAQLDPALEEAALDLGANEWKTFFQITLPLIWPAIFSAALLAFTLSLDDFVITFFTAGVGSTT
LPLFVYGMIKFSVTPAINAISTLMLVASLILVASSLFIDKLGNKKNA
>Mature_287_residues
MKQIDLFIRSVGKFGLWLNATFSFAFLYLPILILVIYSFNNSRFNAVWRGFTLKWYDNLLQEFSANAISNVMIWEALTNS
LFVATISTLLATIFGTMIALALERFRFPGRNVLEAILFLPIIIPEITIGISLLVFFSLGFQLIENILGIRLVLGLPTVII
GHIVFSISFVVVTVRARVAQLDPALEEAALDLGANEWKTFFQITLPLIWPAIFSAALLAFTLSLDDFVITFFTAGVGSTT
LPLFVYGMIKFSVTPAINAISTLMLVASLILVASSLFIDKLGNKKNA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=251, Percent_Identity=40.2390438247012, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787081, Length=247, Percent_Identity=42.5101214574899, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787714, Length=264, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788764, Length=179, Percent_Identity=32.9608938547486, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786980, Length=213, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31803; Mature: 31803

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIDLFIRSVGKFGLWLNATFSFAFLYLPILILVIYSFNNSRFNAVWRGFTLKWYDNLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
QEFSANAISNVMIWEALTNSLFVATISTLLATIFGTMIALALERFRFPGRNVLEAILFLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IIIPEITIGISLLVFFSLGFQLIENILGIRLVLGLPTVIIGHIVFSISFVVVTVRARVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPALEEAALDLGANEWKTFFQITLPLIWPAIFSAALLAFTLSLDDFVITFFTAGVGSTT
HCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LPLFVYGMIKFSVTPAINAISTLMLVASLILVASSLFIDKLGNKKNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQIDLFIRSVGKFGLWLNATFSFAFLYLPILILVIYSFNNSRFNAVWRGFTLKWYDNLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
QEFSANAISNVMIWEALTNSLFVATISTLLATIFGTMIALALERFRFPGRNVLEAILFLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IIIPEITIGISLLVFFSLGFQLIENILGIRLVLGLPTVIIGHIVFSISFVVVTVRARVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPALEEAALDLGANEWKTFFQITLPLIWPAIFSAALLAFTLSLDDFVITFFTAGVGSTT
HCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LPLFVYGMIKFSVTPAINAISTLMLVASLILVASSLFIDKLGNKKNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]